1. Discussion on pT3 staging in TNM staging of AJCC 8th edition gallbladder carcinoma
Facai YANG ; Jingdong LI ; Anqi DUAN ; Zhiyuan BO ; Ningjia SHEN ; Bin ZHU ; Wenlong YU ; Longjiu CUI ; Xiang WANG ; Lianghe YU ; Lei YIN ; Xiaohui FU ; Yongjie ZHANG ; Yinghe QIU
Chinese Journal of Surgery 2019;57(11):834-839
Objective:
To discuss the rationality of stage pT3 in the AJCC 8th TNM criteria of gallbladder carcinoma.
Methods:
A retrospective study was performed to analyze the clinical and pathological data of 88 patients with pT3 gallbladder carcinoma admitted to Department of Second Biliary Surgery of Eastern Hepatobiliary Surgery Hospital, affiliated to Naval Medical University from May 2013 to September 2018.pT3 stage tumors were divided into two groups: (1) pT3a stage: tumors had penetrated serosa but not directly invaded liver and/or an adjacent organ or structure; (2) pT3b stage: tumor penetrating serosa and directly invaded liver and/or an adjacent organ or structure. There were 45 patients with pT3a stage, including 15 males and 30 females, aged 36 to 80 years, with a median age of 59 years; 43 patients with pT3b, including 24 males and 19 females, aged 41 to 78 years old, median aged 63 years old.Patients with pT3a and pT3b were further divided into two groups respectively: radical resection group and extended radical resection group according to surgical radicalization. Independent sample