Objective:In Order to study on biological effects of rotary magnetic field (RMF) conveniently and precisely,a digital-controlled instrument for generating RMF,which is based on a single-chip microcomputer,is developed.Methods:The precise frequency of RMF is controlled by using microcomputer to drive step motor,and intensity of magnetic field is measured by using 10-bit Analog-to-Digital(A/D) Converter module which is integrated in microcomputer.According,the technique of LCD screen to display relative information,such as,frequency,intensity of magnetic field,time of timer,is applied.Additionally, touching buttons,which is simple and convenience to use,is selected.Results:This instrument works very well with high precise frequency,and its operation is simple.As a example for this instrument,that biological effect of RMF on the the prostate about SD rat is significantly is found.Conclusion:This instrument may be used to research and study on biological effects of RMF widely.

The teaching of experiment about how to guide medical students to design and make auscultative system is given.By designing and making auscultative system,the student can not only understand computer system and its interface,including amplifier circuit,filter circuit,A/D and D/A circuit,but also train their ability to use hand and the knowledge learned,thus arousing their innovation and creativity.

Transistor amplifier is the key and difficult points in the teaching of medical electronics,however,most of the teaching materials on this content is insufficient.Meanwhile,medical students have little knowledge of engineering,so it is difficult for them to grasp the related knowledge.We introduced ‘ superposition theorem’ into the relevant teaching.Teaching practice proved that this reform made it easier for medical students to have an in-depth understanding of the content and better teaching effect was achieved.

A new urine analysis core module based on high performance 32-bit microprocessor and high precision color sensor was presented. A novel optical structure and a specific circuit were applied to improve measurement precision and temperature was used to compensate for results in this core module. The information of urine test peice, such as all original data and color RGB value, reflectivity, semi-quantitative level, etc. can be output. The results showed that the measuring precision was about 95% or above with ideal stability and reliability using this presented core module, which can be conveniently applied in various urine analyzers, and can greatly decrease the cost of urine analyzers in development and production.
Color ; Equipment Design ; Microcomputers ; Reproducibility of Results ; Temperature ; Urinalysis ; instrumentation ; methods

Counting-type analog quantity (CAQ), a new conception, is introduced in this article. CAQ possesses some features of analog quantity and digital quantity, that is to say, it has double features. By analysis, two kinds of CAQ are found: one is width-modulated countable pulse series, the other is frequency-modulated countable pulse series. Furthermore, the method of generating CAQ is described and its double feature is also proved. It is very convenient to realize single-channel or multi-channel analog-to-digital (A/D) conversion by using CAQ without utilizing present integrated A/D conversion chip. In this paper, for proving its feasibility, multi-channel telemetering computer system for dynamic information about human vascular wall,a typical example of using CAQ in medicine, is expatiated. The typical example clearly indicates: not only the method for application of CAQ is simple and viable, but also the application of CAQ is very wide.
Analog-Digital Conversion ; Blood Vessels ; physiology ; Computer-Aided Design ; Elasticity ; Electronics, Medical ; instrumentation ; Humans ; Monitoring, Physiologic ; instrumentation ; Signal Processing, Computer-Assisted

Objective evaluation of driver drowsiness is necessary toward suppression of fatigued driving and prevention of traffic accident. We have developed a new method in which we utilized pupillary diameter variability (PDV) under spontaneous pupillary fluctuation conditions. The method consists of three main steps. Firstly, we use a 90s long infrared video of pupillogram infrared-sensitive CCD camera. Secondly, we employed edge detection algorithm based on curvature characteristics of pupil boundary to extract a set of points of visible pupil boundary, and then we adopted these points to fit a circle to obtain the diameter of the pupil in current frame of video. Finally, the values of PDV in 90s long video is calculated. In an experimental pilot study, the values of PDV of two groups were measured. One group rated themselves as alert (12 men), the other group as sleepy (13 men). The results showed that significant differences could be found between the two groups, and the values were 0.06 +/- 0.005 and 0.141 +/- 0.042, respectively. Taking into account of the knowledge that spontaneous pupillary fluctuation is innervated by autonomic nervous system which activity is known to change in parallel with drowsiness and cannot be influenced by subjective motive of people. From the results of the experiments, we concluded that PDV could be used to evaluate driver fatigue objectively.
Algorithms ; Automobile Driving ; Fatigue ; diagnosis ; physiopathology ; Humans ; Iris ; anatomy & histology ; Monitoring, Physiologic ; methods ; Pupil ; physiology

Based on theoretic analysis, a new method for measuring linearity of physiological instrument and its inner unit circuits is provided. In this method, the sawtooth wave signal, which includes a base wave and its odd-even times harmonic waves, is used to act as input signal, then the linearity of physiological instrument and its inner unit circuits can be measured by analyzing the shape and frequency property of the output signal. The results of experiment show this method is quick and convenient for measuring the linearity of physiological instrument and its inner unit circuits.
Diagnosis, Computer-Assisted ; methods ; Humans ; Monitoring, Physiologic ; instrumentation ; Signal Processing, Computer-Assisted

An opened instrument with liquid crystal display (LCD) for generating and measuring physiological signal is introduced in this paper. Based on a single-chip microcomputer. the instrument uses the technique of LCD screen to display signal wave and information, and it realizes man-machine interaction by keyboard. This instrument can produce not only defined signal in common use by utilizing important saved data and relevant arithmetic, but also user-defined signal. Therefore, it is open to produce signal. In addition, this instrument has strong extension because of its modularized design as computer, which has much function such as displaying, measuring and saving physiological signal, and many features such as low power consumption, small volume, low cost and portability. Hence this instrument is convenient for experiment teaching, clinic examining, maintaining of medical instrument.
Analog-Digital Conversion ; Equipment Design ; Humans ; Microcomputers ; Monitoring, Physiologic ; instrumentation ; Signal Processing, Computer-Assisted ; instrumentation ; Software

In recent years, the rapid development of the Internet of things technology has opened up broad prospects for the integration of the Internet of things technology into medical education to train interdisciplinary talents who master knowledge in both medicine and engineering. The researchers incorporated the Internet of things technology in the experimental teaching of the course "Biomedical sensors", reformed the contents and methods of experimental teaching, and developed and designed a biomedical sensor experimental teaching system based on the Internet of things technology. As a result, the new experimental teaching can help students understand the system design methods of the Internet of things in smart medical devices and cultivate their practical ability and innovative ability, which has obtained preliminary teaching results.