ObjectiveTo investigate the event-based prospective memory (EBPM)and time-based prospective memory( TBPM )in late-onset depressive patients and to explore the relationships between prospective memory and depressive symptoms.Methods 32 late-onset depressive patients and 30 normal controls matched in age,gender and education were assessed with a neuropsychological battery of tests including EBPM and TBPM tasks.The patients were also assessed with Hamilton Depression Scale (HAMD).ResultsA statistically significant in EBPM was observed between patients with late-onset depression and normal controls (2.31 ± 1.06 vs 3.07± 0.87,t =- 3.052,P ＜ 0.01) and the same result in TBPM (2.03 ± 0.93 vs 2.67 ± 0.92,t =- 2.695,P ＜0.01 ).The negatively correlate was showed between the total scores of HAMD and EBPM ( r =- 0.436,P =0.013 ),TBPM ( r =- 0.467,P =0.007 ) in the patients.ConclusionThe results suggest late-onset depressive patients impair both EBPM and TBPM.Prospective memory shows correlation with depressive symptoms in the patients.

Objective To investigate the event-based prospective memory(EBPM)and time-based prospective memory(TBPM)in schizophrenia patients with concomitant metabolism syndrome,and to provide theory basis for early intervention and treatment.Methods According to inclusion standard,50 schizophrenia patients with concomitant metabolism syndrome and 50 schizophrenia patients without metabolism syndrome matched in age,gender and education were assessed with a neuropsychological battery of tests including EB-PM and TBPM tasks.Results In the EBPM task,there was significant difference between schizophrenia pa-tients with and without metabolism syndrome (3.46±0.91 vs 3.86±0.81, t=-2.326, P=0.022).A statistically significant difference in TBPM was observed between schizophrenia patients with and without metabolism syn-drome (3.02±1.12 vs 3.78±0.89, t=-3.770, P=0.000).Conclusion The schizophrenia patients with me-tabolism syndrome have severer prospective memory impairment than those without metabolism syndrome.

Objective: To investigate the event-based prospective memory(EBPM) and time-based prospective memory(TBPM) in patients with euthymic bipolar disorder and to explore the relationships between prospective memory and temperament. Methods: Fifty patients with euthymic bipolar disorder(case group) and forty-five demographic characteristic matched healthy controls(control group) were recruited.The neuropsychological battery of tests including EBPM and TBPM tasks were used to measured the prospective memory, and all participants completed the Chinese version of short temperament evaluation of the memphis(TEMPS-A). The differences in prospective memory and temperament between the case group and control group were compared by t test.Pearson correlation analysis was used to analyze the correlation between prospective memory and temperament. Results: A statistically significant in EBPM was observed between patients with euthymic bipolar disorder and health controls ((3.66±0.69) vs (4.18±0.83), t=-3.313, P<0.01) and the same result was showed in TBPM ((3.06±0.96) vs (3.89±0.75), t=-4.674, P<0.01). The total score of TEMPS-A ((18.82±4.49) vs (9.69±3.37), t=11.106, P<0.01) and the scores of all the subscales were higher in case group than those in control group.The negative correlation was showed between the scores of depression temperament and TBPM (r=-0.425, P=0.002) in the case group. Conclusion The results suggest both EBPM and TBPM have impaired, and TBPM correlates with depression temperament moderately in the patients with euthymic bipolar disorder.

Objective:To explore the relationship between resilience and social function in patients with bipolar disorder.Methods:A total of 127 patients with bipolar disorder were investigated using the questionnaires of Connor-Davidson resilience scale (CD-RISC) and scale of social function of psychosis inpatients (SSFPI). The relationship between resilience and social function was analyzed by correlation analysis and stepwise multiple regression analysis.Results:The scores of resilience and social function of patients with bipolar disorder were (45.32±13.84) and (31.38±5.09) respectively.And the CD-RISC score of patients with bipolar disorder was positively correlated with the SSFPI total score ( r=0.499, P<0.01). The stepwise multiple regression analysis showed that the social function of patients with bipolar disorder was affected by tenacity( β=0.336, t=3.42, P=0.001), the age of first onset( β=0.186, t=2.416, P=0.017)and strength( β= 0.205, t=2.053, P=0.042), accounted for 29.9% of the total variation. Conclusion:The resilience level of patients with bipolar disorder is positively related with social function.Resilience levels can influence social function, so effective and targeted measures should be taken to improve their resilience level in order to improve social function of patients with bipolar disorder.