1.Ultrasound diagnosis of postoperative foreign body (gauze)
Journal of Vietnamese Medicine 1999;233(2):63-64
The Viet Duc Hospital found 6 cases of the postoperative left gauze by ultrasound during 1997-1998. The diagnosis based on the clinical symptoms (infectious sign), operative history, position and size of foreign body. The foreign bodies found earliest in the 20th days and longest in the 4th years after an operation. The form, size and structure of the foreign bodies have not been changed through the round of examination.
Ultrasonography
;
Foreign Bodies
;
Diagnosis
2.Epidemiological survey on Japanese encephalitis in children at Hai Phong city, 1990-2000
Journal of Preventive Medicine 2004;14(2):37-40
Result of the retrospective survey in 720 patients of Japanese encephalitis (JE) during 1990-2000 in Hai Phong Children's Hospital was showed that: age group from 5 to 9 was 51.5%, under 5 ages 29.9% and from 10-15 ages was 19.6%. The age groups of under 5, 5-9 and 10-15 years old were 28.9%, 51.5% and 19.6%, respectively. The prevalence in the rural area was higher than these in urban area. The morbidity occurred mainly in May-June. 67.8% (99/146) were detected positive by using MAC-ELISA
Epidemiology
;
Encephalitis, Japanese
;
child
3.Side effects of Japanese encephalitis (JE) vaccine produced in Vietnam with different vaccinated doses
Journal of Preventive Medicine 2004;14(2):41-44
320 healthy pupils were examined at two primary school and secondary school in Tan Tien commune, An Hai district, Hai Phong city, among them 257 pupils were selected. Those pupils were divided randomly into 4 groups. There was the age from 6 to 14 in each group. JE vaccine produced by National Institute of Hygiene and Epidemiology, Hanoi was vaccinated three times: first dose and second dose with a week interval, third dose a year after with different doses: 1ml, 0.75ml, 0.5ml and 0.1ml, for children of age from 6 to 14. The side effect mainly was slight pain on the injection's spot. Almost of cases had slight fever (< 380C), during only 1-2 days after injection
Japanese Encephalitis Vaccines
;
adverse effects
;
epidemiology
;
Pupil
;
child
4.Immunoresponse after immunization of Vaccine of Japanese encephalitis at various doses that produced by Hanoi National Institute of Hygiene and Epidemiology
Journal of Medical and Pharmaceutical Information 2001;4():25-28
262 children aged 6-14 years old were randomly divided into 4 groups receiving different vaccine doses of 1ml; 0,75ml; 0,1 ml. After the interval of one week between two injections the results showed that antibody response manifested effectively on all 4 groups.
Japanese Encephalitis Vaccines
;
Immunization
5.Study on bacterial air pollution - the relation of it with respiratory tract diseases in some areas of Thai Nguyen city.
Journal of Practical Medicine 2002;435(11):21-25
By a descriptive study and a design-cross sectional study; author has conducted a study on a real situation of bacterial air pollution and related respiratory diseases in some regions in Thai Nguyen city, the results showed that: 1. The Quan Trieu ward where is bacterial polluted is 3 times higher than a control one. 2. In this ward, a number of bacteria in the afternoon is higher than those in the morning. 3. Bacterial air pollution is related to the prevalence rate of respiratory diseases in the studied regions. From above findings, author has given several recommendations as follows: - In ARI programme, environment factors should be paid more attention to. - Traffic system should be more upgraded. In order to control dust, watering cars should regularyly operate in the main streets of Thai Nguyen city.
Air pollution
;
respiratory tract diseases
6.Safety of Balloon Kyphoplasty in the Treatment of Thoracic Osteoporotic Vertebral Compression Fractures in Vietnamese Patients
Dinh-Hoa NGUYEN ; Duc-Dat VU ; Thi-Ngoc-Ha DOAN ; Hoang-Long VO
Clinics in Orthopedic Surgery 2020;12(2):209-216
Background:
The evidence for the efficacy and safety of balloon kyphoplasty (BKP) in treating the Vietnamese patients is sparse. There is no convincing evidence regarding BKP’s efficacy in Vietnamese patients, especially in the patients with thoracic osteoporotic vertebral compression fractures (VCFs). This article aims to evaluate the outcomes of restoring the body height of the compressed thoracic vertebrae in patients undergoing BKP.
Methods:
We prospectively enrolled 65 consecutive patients with thoracic VCFs (73 vertebrae) due to osteoporosis who were treated with BKP between June 2018 and May 2019.
Results:
A trocar was inserted through the pedicle in 84.9% (62/73) and beside the pedicle in 15.1% (11/73). The mean amount of mixed cement injected was 4.1 ± 1.1 mL (range, 1.5–7 mL). Cement leakage was radiographically confirmed in 30.8% of 65 patients. Among patients with complications caused by cement extravasation, the leakage was through the anterior margin of the vertebrae in 15.4%, through the vertebral disc in 12.3%, and through the posterior margin of the vertebrae in 3.1%. In the last 3.1% of patients, there was no clinically notable lesions of the nerve roots or spinal cord. The mean visual analog scale score decreased significantly from 7.3 ± 1.1 preoperatively to 3.3 ± 0.6 at 24 hours after surgery, and then to 1.2 ± 1.1 at 3 months after surgery (p < 0.01). The mean reduction in Cobb angle measured on standing radiographs after treatment was 3.7°, showing statistical significance (p < 0.01).
Conclusions
BKP is a minimally invasive treatment effective for immediate pain relief, early motor rehabilitation, and humpback correction. The present study provided convincing evidence to support the use of BKP by spine surgeons and clinical specialists in treating osteoporotic thoracic VCFs in Vietnamese patients.
7.Using Online Respondent Driven Sampling for Vietnamese Youths' Alcohol Use and Associated Risk Factors.
Melvyn W B ZHANG ; Bach Xuan TRAN ; Huong Lan Thi NGUYEN ; Huong Thi LE ; Nguyen Hoang LONG ; Huong Thi LE ; Nguyen Duc HINH ; Tran Dinh THO ; Bao Nguyen LE ; Vu Thi Minh THUC ; Chau NGO ; Nguyen Huu TU ; Carl A LATKIN ; Roger CM HO
Healthcare Informatics Research 2017;23(2):109-118
OBJECTIVES: The average alcohol consumption per capita among Vietnamese adults has consistently increased. Although alcohol-related disorders have been extensively studied, there is a paucity of research shedding light on this issue among Internet users. The study aimed to examine the severity of alcohol-related disorders and other associated factors that might predispose individuals towards alcohol usage in a sample of youths recruited online. METHODS: An online cross-sectional study was conducted with 1,080 Vietnamese youths. A standardized questionnaire was used. Respondent-driven sampling was applied to recruit participants. Multivariate logistic and Tobit regressions were utilized to identify the associated factors. RESULTS: About 59.5% of the males and 12.7% of the total youths declared that they were actively using alcohol. From the total sample, a cumulative total of 32.3% of the participants were drinking alcohol, with 21.8% and 25.0% of the participants being classified as drinking hazardously and binge drinkers, respectively. The majority of the participants (60.7%) were in the pre-contemplative stage. CONCLUSIONS: A high prevalence of hazardous drinking was recognized among online Vietnamese youths. In addition, we found relationships between alcohol use disorder and other addictive disorders, such as tobacco smoking and water-pipe usage. Our results highlighted that the majority of the individuals are not receptive to the idea of changing their alcohol habits, and this would imply that there ought to be more government effort towards the implementation of effective alcohol control policies.
Adolescent
;
Adult
;
Alcohol Drinking
;
Alcohol-Related Disorders
;
Asian Continental Ancestry Group*
;
Cross-Sectional Studies
;
Drinking
;
Humans
;
Internet
;
Male
;
Prevalence
;
Risk Factors*
;
Smoking
;
Surveys and Questionnaires*
;
Vietnam
8.NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts.
Vu Thi THU ; Hyoung Kyu KIM ; Le Thanh LONG ; To Thanh THUY ; Nguyen Quang HUY ; Soon Ha KIM ; Nari KIM ; Kyung Soo KO ; Byoung Doo RHEE ; Jin HAN
The Korean Journal of Physiology and Pharmacology 2016;20(3):305-314
Inflammatory and fibrotic responses are accelerated during the reperfusion period, and excessive fibrosis and inflammation contribute to cardiac malfunction. NecroX compounds have been shown to protect the liver and heart from ischemia-reperfusion injury. The aim of this study was to further define the role and mechanism of action of NecroX-5 in regulating infl ammation and fi brosis responses in a model of hypoxia/reoxygenation (HR). We utilized HR-treated rat hearts and lipopolysaccharide (LPS)-treated H9C2 culture cells in the presence or absence of NecroX-5 (10 µmol/L) treatment as experimental models. Addition of NecroX-5 signifi cantly increased decorin (Dcn) expression levels in HR-treated hearts. In contrast, expression of transforming growth factor beta 1 (TGFβ1) and Smad2 phosphorylation (pSmad2) was strongly attenuated in NecroX-5-treated hearts. In addition, signifi cantly increased production of tumor necrosis factor alpha (TNFα), TGFβ1, and pSmad2, and markedly decreased Dcn expression levels, were observed in LPS-stimulated H9C2 cells. Interestingly, NecroX-5 supplementation effectively attenuated the increased expression levels of TNFα, TGFβ1, and pSmad2, as well as the decreased expression of Dcn. Thus, our data demonstrate potential antiinflammatory and anti-fibrotic effects of NecroX-5 against cardiac HR injuries via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway.
Animals
;
Decorin
;
Fibrosis
;
Heart*
;
Inflammation
;
Liver
;
Models, Theoretical
;
Phosphorylation
;
Rats*
;
Reperfusion
;
Reperfusion Injury
;
Transforming Growth Factor beta
;
Tumor Necrosis Factor-alpha
9.NecroX-5 protects mitochondrial oxidative phosphorylation capacity and preserves PGC1alpha expression levels during hypoxia/reoxygenation injury.
Vu Thi THU ; Hyoung Kyu KIM ; Le Thanh LONG ; Bayalagmaa NYAMAA ; In Sung SONG ; To Thanh THUY ; Nguyen Quang HUY ; Jubert MARQUEZ ; Soon Ha KIM ; Nari KIM ; Kyung Soo KO ; Byoung Doo RHEE ; Jin HAN
The Korean Journal of Physiology and Pharmacology 2016;20(2):201-211
Although the antioxidant and cardioprotective effects of NecroX-5 on various in vitro and in vivo models have been demonstrated, the action of this compound on the mitochondrial oxidative phosphorylation system remains unclear. Here we verify the role of NecroX-5 in protecting mitochondrial oxidative phosphorylation capacity during hypoxia-reoxygenation (HR). Necrox-5 treatment (10 microM) and non-treatment were employed on isolated rat hearts during hypoxia/reoxygenation treatment using an ex vivo Langendorff system. Proteomic analysis was performed using liquid chromatography-mass spectrometry (LC-MS) and non-labeling peptide count protein quantification. Real-time PCR, western blot, citrate synthases and mitochondrial complex activity assays were then performed to assess heart function. Treatment with NecroX-5 during hypoxia significantly preserved electron transport chain proteins involved in oxidative phosphorylation and metabolic functions. NecroX-5 also improved mitochondrial complex I, II, and V function. Additionally, markedly higher peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC1alpha) expression levels were observed in NecroX-5-treated rat hearts. These novel results provide convincing evidence for the role of NecroX-5 in protecting mitochondrial oxidative phosphorylation capacity and in preserving PGC1alpha during cardiac HR injuries.
Animals
;
Anoxia
;
Blotting, Western
;
Citric Acid
;
Electron Transport
;
Heart
;
Mitochondria
;
Oxidative Phosphorylation*
;
Peroxisomes
;
Rats
;
Real-Time Polymerase Chain Reaction
;
Spectrum Analysis
10.Study on the proportion of patients with uncontrolled hypertension among outpatients and related factors at the Internal Medicine Clinic, Hue university of medicine and Pharmacy Hospital
Vu Thao Vy NGUYEN ; Thi Bich Thuy LE ; Pham Phuoc Long DOAN ; Thi Thanh Nhan TRAN ; Phuoc Thuoc DOAN
Hue Journal of Medicine and Pharmacy 2023;13(7):190-197
Background: Hypertension is one of the dangerous chronic diseases. In the treatment of hypertension, controlling blood pressure to achieve treatment target is paramount to prevent dangerous complications and death. The study was conducted to identify the percentage of hypertensive patients who do not achieve treatment target among outpatients at the internal medicine clinic, Hue University of Medicine and Pharmacy Hospital, and explore some related factors. Methods: A cross-sectional study was conducted among 403 hypertensive patients treated as outpatients at the internal medicine clinic. A multivariate logistic regression model was used to identify the related factors. Results: 46.4% of hypertensive patients did not reach the treatment target. Factors related to uncontrolled hypertension were male, non-religion, comorbidities, no reduction in salt intake, the use of coffee/tea, and non-compliance with medication (p < 0.05). Conclusions: The rate of patients with uncontrolled hypertension was still high. The health sector should consider establishing an outpatient management team; strengthening communication activities and advice on diet and drug use in parallel with medical examination and treatment.