1.Diagnosis and treatment of primitive neuroectodermal tumor
Journal of International Oncology 2011;38(8):624-626
Primitive neuroectodermal tumor (PNET) is a kind of malignant tumor, which most often affects children and adolescents. The incidence of PNET has risen recently. PNET has low early diagnosis rate and poor treatment effect. With the application of RT-PCR and FISH in pathological diagnosis, and MRI and PET-CT in imageological diagnosis, as well as the implementation of target treatment and multidisciplinary integrated treatment concept in the treatment, the pathogenesis, diagnosis technology and treatment means of of PNET have made remarkable progress.
2.Research on the Feature of 2,3-Butanediol Post-Treatment for Glutaraldehyde Tanned Bovine Pericardium
Journal of Chinese Physician 2001;0(08):-
0 05), but there were significant difference,as compared with control group (all P
3.Management of low back pain in primary care.
Journal of the Korean Academy of Family Medicine 2000;21(5):586-599
No abstract available.
Low Back Pain*
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Primary Health Care*
4.Ultrasound diagnosis of postoperative foreign body (gauze)
Journal of Vietnamese Medicine 1999;233(2):63-64
The Viet Duc Hospital found 6 cases of the postoperative left gauze by ultrasound during 1997-1998. The diagnosis based on the clinical symptoms (infectious sign), operative history, position and size of foreign body. The foreign bodies found earliest in the 20th days and longest in the 4th years after an operation. The form, size and structure of the foreign bodies have not been changed through the round of examination.
Ultrasonography
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Foreign Bodies
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Diagnosis
6.The expression and significance of serum guanine nucleotide dissociation inhibitor 2 and natural killer cell activation receptor 2D in patients with advanced lung cancer
Clinical Medicine of China 2016;32(1):54-57
Objective To study expression clinical significance of serum guanine nucleotide dissociation inhibitor 2 (RhoGDI2), natural killer ccll activation receptor 2D (NKG2D) in patients with advanced lung cancer.Methods From January 2012 to December 2014,50 cases of middle-late stage lung cancer patients as the research object,20 patients with lung adenocarcinoma, 18 cases of adenocarcinoma of lung, 12 cases with small cell lung cancer;30 cases of phase Ⅲ, 20 cases of Ⅳ;22 cases of lymph node metastasis, 28 cases without lymph node metastasis.From January 2012 to December 2014,50 healthy subjects as control group.Flow cytometry instrument was used to detect NKG2D, and ELISA method was used to detect RhoGDI2.Results The RhoGDI2 level of lung cancer patients in Ⅳ, Ⅲ stage higher than the control group ((70.19±8.54), (49.76 ±7.25) vs (5.62± 1.26) μg/L)), the NKG2D level lower than the control group ((71.49± 5.57)%, (78.97 ±6.62)% vs (84.59±6.96)% ,P<0.05).The RhoGDI2 level of lung cancer patients with stage Ⅳ was higher than that of patients with stage Ⅲ((70.19±8.54) μg/L vs (49.76±7.25) μg/L) ,while the NKG2D level of lung cancer patients with stage Ⅳ was lower than that of patients with stage Ⅲ((71.49±5.57) % vs (78.97 ±6.62) %, P<0.05).RhoGDI2 level of patients with lymph node metastasis was higher than that of patients with no lymph node metastasis((71.32±6.79) μg/L vs (48.29±2.36) μg/L,P<0.01) ,NKG2D level of lymph node metastasis was lower than without lymph node metastasis in patients ((72.36 ± 6.62)%与 (81.27 ±6.86)%, P <0.01).There was negative correlation between serum RhoGDI2, NKG2D expression (r =-4.176, P =0.011).Conclusion There are relationship between the abnormal expression of RhoGDI2 and NKG2D with the clinical stages,lymph node metastasis of the tumor of lung cancer, and has nothing to do with the type of lung cancer.There is negative correlation between the expression of RhoGDI2 and NKG2D.
7.Changes of procalcitonin level in cirrhosis patients complicated with hepatorenal syndrome
Tianjin Medical Journal 2015;(4):393-395
Objective To observe changes of procalcitonin (PCT) level in cirrhosis patients complicated with hepatorenal syn?drome (HRS). Methods Cirrhosis without HRS (Non-HRS group, n=115), cirrhosis with HRS (HRS group, n=28) and control group (40 cases) were enrolled. Levels of serum PCT, C-reactive protein (CRP), Cystatin-C (Cys-C), white blood count, percentage of neutro?phils, serum creatinine and urine creatinine were examined in all participants. Correlation between serum PCT levels and incidence of HRS was analyzed. Correlations between serum PCT levels with CRP, Cys-C, 24 h-Creatinine clearance (24 h-Ccr) were analyzed. Re?sults Among cirrhosis patients, those with increased PCT had higher chance of complication with HRS than those with normal PCT (P=0.026). Levels of serum PCT, CRP and Cys-C are higher in HRS Group than those in Non-HRS group,both which are higher than those incontrol group (P<0.05);Level of 24 h-Ccr is lower in HRS Group than that in non-HRS group, both of which are lower than that in control group (P<0.05). Levels of serum PCT positively correlated to levels of serum CRP and Cys-C but, negatively correlated to levels of 24 h-Ccr. Conclusion Serum PCT level contribute to early infection and renal damage in cirrhosis and might play an im?portant role in development of HRS. It is valuable in giving early information of cirrhosis complicated with HRS.
8.Clinical features and management of small bowel intussusception in children
International Journal of Pediatrics 2015;42(5):511-513
Small bowel intusssusception is relatively rare in children and the manifestation is always atypical.Abdominal ultra-sonography conduces to final diagnosis.It can be classified into transient and persistent small bowel intussusception with their own clinical characteristics respectively.This article systematically reviews the clinical features and treatment advances of small bowel intussusception in children.
9.Research progress of circulating microRNA as a new biomarker of cancer
Cancer Research and Clinic 2013;25(10):708-710
Cancer is one of the most dangerous diseases that threaten human health.The early diagnosis individual treatment and accurate judgement of recurrence play important roles in prognosis.microRNA (miRNA) is a class of small fragments of RNA molecules which has the ability to regulate the gene expression.In recent years,some researchers have begun to focus on it.Studies have shown that the great stability of circulating miRNA in body fluid,as well as the specificity in many types of cancer,which may be important for the diagnosis and prognosis of cancer patients.In this review,the advantages and limitations of circulating miRNA as a new biomarker of cancer are birfly summarized.
10.Sedum freckle capsule combined with hydroquinone cream phonophoresis in the treatment of chloasma
International Journal of Traditional Chinese Medicine 2015;(6):502-504
ObjectiveTo evaluate the clinical efficacy of Sedum freckle capsule combined with hydroquinone cream phonophoresis in the treatment of chloasma.MethodsA total of 180 patients with chloasma were recruited into two groups according to the random number table, 100 in the treatment group and 80 in the control group. The patients in the control group were treated with 2% hydroquinone cream phonophoresis, and those in the treatment group received 2% hydroquinone cream phonophoresis and Sedum freckle capsules, both for 2 months. The symptom and lesion score were usedto evaluate the clinical efficacy. ResultsThe cure rates were 81.00% in the treatment group and 67.50% (χ2=4.320,P=0.038) in the control group at the end of treatment, 92.0% and 76.3% (χ2=5.538,P=0.019) at 2 months follow-up. The total lesion scores at the end of treatment and at 2 months follow-up were significantly lower than before the treatment in the treatment group (1.61 ± 0.84 and 1.30 ± 0.85vs.3.48 ± 1.02;t=14.152, 16.419, allP<0.01) and also in the control group (2.04 ± 0.61 and 2.03 ± 0.51vs.3.45 ± 1.09;t=10.097, 10.554, allP<0.01). The total lesion score at the end of treatment and at 2 months follow-up were significantly lower than in the treatment group was significantly decreased than the control group (t=3.839, 6.767; allP<0.01).ConclusionSedum freckle capsule combined with hydroquinone cream phonophoresis could effectively treat patients with chloasma.