1.Report of epidermal growth factor receptor mutation in a patient with combined small cell lung cancer.
Haiying WANG ; Zhuang TIAN ; Yabin ZOU ; Lizhi HAN ; Xiumei DUAN
Chinese Journal of Pathology 2014;43(1):45-46
Adenocarcinoma
;
genetics
;
metabolism
;
pathology
;
Biopsy
;
CD56 Antigen
;
metabolism
;
DNA-Binding Proteins
;
metabolism
;
Gene Deletion
;
Humans
;
Keratin-7
;
metabolism
;
Lung Neoplasms
;
genetics
;
metabolism
;
pathology
;
Male
;
Middle Aged
;
Receptor, Epidermal Growth Factor
;
genetics
;
metabolism
;
Small Cell Lung Carcinoma
;
genetics
;
metabolism
;
pathology
;
Synaptophysin
;
metabolism
;
Transcription Factors
2.Endolymphatic sac tumor: report of a case.
Lingling TONG ; Lizhi HAN ; Lirong BI
Chinese Journal of Pathology 2015;44(9):671-672
3.The clinical characteristics of interstitial lung disease in patients with dermatomyositis and polymyositis
Peizhen WANG ; Jianlong GUAN ; Lizhi BAO ; Jingming LI ; Xinghai HAN
Chinese Journal of Rheumatology 2008;12(12):826-828
Objective To analyze the clinical features,and prognosis of the interstitial lung disease (ILD) in patients with dermatomyositis (DM) and polymyositis (PM) by chest X-ray,chest high-resolution CT scan (HRCT) and pulmonary lung function.Methods Thirty-three patients hospitalized with DM/PM associated ILD were retrospectively analyzed.Results Thirty-three patients with ILD were confirmed by HRCT.Abnormal pulmonary function tests were available in 82% of patients.Clinical-imaging analysis revealed that the pathological features of ILD were non-specific interstitial pneumonia (NSIP,57%) and unusual interstitial pneumonia (UIP,25%).UIP types showed a poor prognosis and high mortality (70%).Conclusion This study shows that HRCT is more sensitive for the diagnosis of ILD than lung function tests and chest X-ray.Combined HRCT and chest X-ray with lung function tests and blood gas analysis have shown that the major pathological types of ILD are NSIP and UIP,in which UIP are associated with high mortality and poor prognosis.
5.The diagnostic value of CT and MRI on peripheral primitive neuroectodermal tumors
Jiangyong LIU ; Jia SONG ; Xiaohua ZENG ; Wencai HUANG ; Zhiqiang SUN ; Lizhi HAN ; Lin ZHAO ; Jing XIONG
Chinese Journal of Postgraduates of Medicine 2016;39(3):224-228
Objective To evaluate the imaging performance and characteristics of peripheral primitive neuroectodermal tumors (pPNET), in order to raise awareness of the disease and the diagnostic accuracy. Methods Thirteen patients with pPNET who confirmed by puncture or pathology were enrolled in this study. The CT and MRI features were retrospectively analyzed. Four patients received simple routine CT examination, and 9 patients had MRI examination based on X-ray, CT examination. Results The part of body involved was more widely.Two patients occurred in the sinuses, 1 patient in the chest wall, 1 patient in the lung, and 3 patients in the abdominal and pelvic(1 patient involved the pelvic floor through the pelvic wall lesions to basins), 1 patient in the spine, and 5 patients located in the extremities. The characteristics of pPNET by CT and MRI in soft tissue of 8 patients showed single large soft tissue mass, and the biggest was 11.2 cm × 10.6 cm. In bonds and joints of 5 patients, CT and MRI showed wide range of soft tissue mass, mixed internal signal/density with obviously uneven enhancement, significant bone destruction and dissolvable osseous changes, and no obvious tumor bone and calcification. Conclusions Each site has its relative imaging characteristics of pPNET. CT and MRI can show lesions involving the scope, internal structure, with or without adjacent tissue invasion and metastasis, and provide guidance for clinical treatment and selecting treatment regimen. But in the end, it depends on the diagnosis of pathological and immunohistochemical examination.
6.Study Progress on Acupoint Specificity
Guoyan LI ; Xia LI ; Shuqin LI ; Lizhi SUN ; Wenyong HAN ; Baoguo WNAG
Shanghai Journal of Acupuncture and Moxibustion 2016;35(4):383-387
It’s still controversial whether there is specificity of acupoints, because numerous studies showed that stimulation to acupoints and sham acupoints produced parallel clinical efficacies. For example, acupoint specificity was not detected when Visual Analogue Scale was adopted to evaluate pain, while hemodynamic and neuroimaging studies suggested the existence of acupoint specificity. This article reviewed and summarized relevant studies that supported or didn’t support acupoint specificity. Further researches are required to prove the existence of specificity of acupoints.
9.Analysis of etiology and clinical characteristics of syncope in children
Xia YU ; Lishuang SUN ; Lizhi HAN ; Delei ZHANG ; Qianqian WANG ; Jinghui SUN
Journal of Clinical Pediatrics 2013;(7):605-608
Objectives To analyse the etiology and clinical characteristics of syncope in children. Methods The clinical data of 128 children with syncope were retrospectively analyzed. Results According to the definition of syncope and supporting test results, 20 cases of non-syncopal conditions were excluded. In 108 cases of syncope, there were 70 cases (64.81%) of neurally mediated syncope, 8 cases (7.41%) of cardiogenic syncope, and 24 cases (22.22%) of unexplained syncope. Eighty-five cases (78.71%) had incentives before the onsets. Twenty-one cases (19.44%) had the family histories of syncope. One case (0.93%) had the family history of sudden death. The neurally mediated syncope and cardiogenic syncope had the feature of recurrent attacks. The VVS were preceded by limbs weakness, pale complexion, darkness in front of eyes, hearing loss, nausea and chest pain, the POTS by palpitation, chest pain and weakness, the OH by darkness in front of eyes, pale complexion and hearing loss, and the car-diogenic syncope by precordial discomfort, pain and chest pain. Conclusions The VVS is one of the most common cause of syn-cope in children. The onsets of the various types of syncope often have incentives and are preceded by some symptoms. Most of them have the feature of recurrent attacks.
10.A comparative study of GASMAN software and traditional way in the teaching of inhalation anes-thesia
Wenyong HAN ; Xia LI ; Fei WANG ; Guoyan LI ; Lizhi SUN ; Min LI
Chinese Journal of Medical Education Research 2016;15(1):55-57,58
Objective To compare and observe the effect of GASMAN software computer aided and traditional teaching method in the teaching of inhalation anesthesia. Methods 48 members of interns who need to enter the inhalation anesthesia department to study the theory of inhalation anesthesia were ran-domly divided into either GASMAN software group or traditional group with 24 people in each group, using the above two methods to carry on the study of inhalation anesthesia. After the end of the teaching course, the study effect and the satisfaction degree of the two groups of students were investigated by the written exam and questionnaire. SPSS 11.5 was used for statistical analysis, using±s to express measurement data. The results of the examination were compared with the independent sample t test, and the satisfaction survey feedback was compared with chi square test, The difference was statistically significant (P<0.05 ). Result The mean score of GASMAN software group (95.4 ±2.7) was significantly higher than that of tra-ditional group (85.0 ±3.5) (t=11.5,P=0.000). Satisfaction survey results showed that GASMAN computer assisted instruction software learning was easier for students to accept, and there were significant difference between two groups (P=0.001). Conclusion Teaching mode of GASMAN software is a good learning technique of inhalation anesthesia, which is worthy of promotion.