1.Progress of risk factors for mortality in children with pneumonia
International Journal of Pediatrics 2020;47(8):565-568
Pneumonia is one of the leading causes of death in children under five years of age worldwide.Scholars at home and abroad have done more researches on the risk factors of death from pneumonia in children.They thought that risk factors for pneumonia deaths in children may include: infants, females, cold weather, lack of breastfeeding, malnutrition, infections with specific pathogens, underlying diseases, social and socioeconomic factors(such as air pollution, young mothers, low maternal education, low socioeconomic status of parents), etc.However, with the change of social environment, there are also increasing risk factors for pneumonia deaths in children.This review focuses on the risk factors of death from pneumonia in children.
2.Observation and analysis of the individual behavior with weaning of infant Rhesus Monkeys
Yanyan LI ; Lixiong CHEN ; Sudong QI ; Junbin WANG ; Fengmei YANG ; Yuan ZHAO ; Shuaiyao LU ; Wenhai YU ; Zhanlong HE
Chinese Journal of Comparative Medicine 2014;(5):35-41
Objective To understand the characteristics and rules of behavior and preliminary study on the change of psychological state and behavior of infant rhesus monkeys after weaning by artificial feed .Methods 290 infant rhesus monkeys were born in 2012, individual behavior of infant rhesus monkeys were observed and recorded by the methods of ad libitum sampling and chronography .Results The behavior of huddling , sucking finger and sucking body of companion were observed in the first month , the behavior of huddling and sucking finger were significantly increased in the second and third month(P <0.05), sucking body of companion in second month were significantly higher than the first month (P <0.05);the new behavior pacing , sucking genitalia and mounting were observed in the second month , pacing and sucking were significantly increased in the third month ( P <0.05 ) , mounting did not have obvious change; in the third month , sucking toe behavior ware recorded and did not change with time; The proportion of huddling behavior occurred between female and female was significantly higher than opposite sex or male in the same cage .The male infant monkeys were more likely to occurred pacing behavior than female .Sucking body of companion and sucking finger behavior of male were significantly lower than the female infant monkeys ( P <0.05 ) .There was no significant difference of sucking toe behavior .Conclusions 7 behaviors were recorded during the whole stage of observation , huddling behavior , pacing behavior , sucking toe behavior , sucking finger behavior , sucking genitalia behavior , sucking body of companion behavior and mounting behavior respectively , and 7 behaviors were increased by degrees with time .Huddling behavior to reflect fear psychology;sucking behavior to represent physiological demand and defensive psychology ;pacing was insignificant behavior in the initial stage , then to reflect psychological anxiety of rhesus monkeys .Provided a way and model on assessment of psychology, praxiology, to study and research the change of psychological state and behavior of early weaning infants .
3.Risk factors for malignant middle cerebral artery infarction: a comparison of young and middle-aged and elderly patients
Lingyu SUN ; Yuhua FAN ; Qi TAN ; Zhe LI ; Liping ZENG ; Can HUANG ; Lixiong LIU ; Lin LIU
International Journal of Cerebrovascular Diseases 2017;25(12):1073-1078
Objective To investigate the risk factors for malignant middle cerebral artery infarction (MMI) in different age groups.Methods Patients with middle cerebral artery infarction were analyzed retrospectively.They were divided into a young and middle-aged group (< 60 years) and an elderly group (≥60 years).The demography and vascular risk factors,stroke etiologies,baseline blood pressure,drug use before onset and common blood test results in patients with MMI and non-MMI were compared in general cases and each age group.Multivariate logistic regression analysis was used to determine the independent risk factors for MMI.ResultsA total of 912 patients with middle cerebral artery infarction were enrolled,including 299 females (32.79%) and 613 males (67.21%);401 young and middle-aged patients (43.97%) and 511 elderly patients (56.03%);159 patients in the MMI group (17.43%),and 753 (82.57%) in the non-MMI group.Multivariable logistic regression analysis showed that hypertension (odds ratio [OR]6.962,95% confidence interval [CI] 1.349-35.934;P=0.021) and NIHSS score (OR 1.551,95% CI 1.384-1.737;P <0.001) were the independent risk factors for MMI.Subgroup analysis showed that NIHSS score (OR 1.402,95% CI 1.239-1.588;P<0.001) was an independent risk factor for MMI in young and middle-aged patients;hypertension (OR 10.752,95% CI 1.213-95.295;P =0.033),diastolic blood pressure (OR 1.080,95% CI 1.002-1.164;P=0.044),and NIHSS score (OR 1.504,95% CI 1.281-1.765;P< 0.001) were the independent risk factor for MMI in the elderly patients,while systolic blood pressure (OR 0.938,95% CI 0.893-0.986;P =0.011) was an independent protective factor.Conclusions The baseline NIHSS score was an independent risk factor for MMI in each age group.Hypertension and diastolic blood pressure were the independent risk factors for MMI in the elderly patients,while systolic pressure was an independent protective factor.Therefore,timely NIHSS assessment and appropriate hypertension management had important significance for the prevention and treatment of MMI.