1.CT Detection of Hepatocellular Carcinoma in Advanced Liver Cirrhosis: Correlation of Helical CT and Explanted Liver.
Jae Hoon LIM ; Min Ju KIM ; Liu Wei CHIANG ; Hyo Keun LIM ; Cheol Keun PARK ; Seung Woon PAIK ; Kwang Cheol KOH ; Jae Won JOH
The Korean Journal of Hepatology 2002;8(2):201-208
OBJECTIVE: The objective of this study was evaluate the diagnostic efficacy of three-phase helical dynamic CT in the detection of hepatocellular carcinomas in patients with advanced liver cirrhosis. MATERIALS AND METFODS: Three-phase helical dynamic CT in 77 patients with advanced liver cirrhosis was evaluated prospectively before orthotopic liver transplantation. The histopathologically confirmed hepatocellular carcinomas in the explanted livers were compared with pretransplantation CT results by one-to-one correlation. RESULTS: Histopathologic examination of the explanted livers revealed 72 hepatocellular carcinomas in 41 patients. The size of the hepatocellular carcinomas was 0.5-14.0 cm (mean, 1.6 cm). The use of helical dynamic CT enabled the detection of 38 of 72 hepatocellular carcinomas (sensitivity, 53%). Fifteen of 35 (43%) hepatocellular carcinomas smaller than 2 cm and 23 of 37 (62%), hepatocellular carcinomas ranging from 2.0 cm to 14.0 cm were detected. Patient sensitivity and specificity in the detection of hepatocellular carcinoma were 81% (33/41) and 94% (34/36), respectively. CONCLUSIONS: Three-phase helical dynamic CT is insensitive for detection of hepatocellular carcinomas in patients with advanced liver cirrhosis, especially for hepatocellular carcinomas smaller than 2 cm.
Adolescent
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Adult
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Biopsy
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Carcinoma, Hepatocellular/complications/pathology/*radiography/surgery
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Female
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Human
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Liver/*pathology
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Liver Cirrhosis/*complications
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Liver Neoplasms/complications/pathology/*radiography/surgery
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Male
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Middle Aged
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Prospective Studies
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Sensitivity and Specificity
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*Tomography, Spiral Computed
2.Foreign Body Granulomas Simulating Recurrent Tumors in Patients Following Colorectal Surgery for Carcinoma: a Report of Two Cases.
Sang Won KIM ; Hyeong Cheol SHIN ; Il Young KIM ; Moo Joon BAEK ; Hyun Deuk CHO
Korean Journal of Radiology 2009;10(3):313-318
We report here two cases of foreign body granulomas that arose from the pelvic wall and liver, respectively, and simulated recurrent colorectal carcinomas in patients with a history of surgery. On contrast-enhanced CT and MR images, a pelvic wall mass appeared as a well-enhancing mass that had invaded the distal ureter, resulting in the development of hydronephrosis. In addition, a liver mass had a hypointense rim that corresponded to the fibrous wall on a T2-weighted MR image, and showed persistent peripheral enhancement that corresponded to the granulation tissues and fibrous wall on dynamic MR images. These lesions also displayed very intense homogeneous FDG uptake on PET/CT.
Adult
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Aged
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Colorectal Neoplasms/pathology/*surgery
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Contrast Media/diagnostic use
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Diagnosis, Differential
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Fluorodeoxyglucose F18/diagnostic use
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Granuloma, Foreign-Body/complications/*diagnosis
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Humans
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Hydronephrosis/etiology
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Image Enhancement/methods
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Liver/pathology/radionuclide imaging
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Liver Neoplasms/*diagnosis/secondary
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Magnetic Resonance Imaging
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Male
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Pelvic Neoplasms/*diagnosis/secondary
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Pelvis/pathology/radiography
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Positron-Emission Tomography
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Radiopharmaceuticals/diagnostic use
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Tomography, X-Ray Computed