197 cases with primary hepatocarcinoma admitted to Viet Duc Hospital between January 1992 to December 1996 were involved in this retrospective study. Mean age of patients was 45.9. Male to female ratio was 3 to 1. Among these, time of death was known exactly in 90 patients. Results showed that the mean time of survival was 3.96 months, ranged 1 to 12 months. Time of survival was longer in the operable group compared with the non-operable group. Other factors such as age, gender, red and white cell counts, protein level in serum and number of liver tumors did not affect to survival of patients. Treating by traditional medicines can increase the time of survival. Mean bedridden time before death was 19.3 days, ranged from 1 to 180 days. Symptoms observed commonly before death were wasting, abdominal bloating, severe pain, breathing difficulty, yellow skin, dark-colour stool, coma and high fever
Liver Neoplasms ; Medicine, Traditional ; surgery ; diagnosis

OBJECTIVEThis review discusses the current status and progress in studies on gastric cancer with liver metastasis (GCLM), involving the routes, subtypes, and prognosis of GCLM; the genes and molecules associated with metastasis; the feasibility and value of each imaging modality; and current treatment options.

DATA SOURCESThe data used in this review were mainly from Medline and PubMed published in English from 2005 to August 2010. The search terms were "gastric cancer" and "liver metastasis".

STUDY SELECTIONArticles regarding the characteristics, diagnostic modalities, and various therapeutic options of GCLM were selected.

RESULTSThe prognosis of GCLM is influenced by the clinicopathological characteristics of primary tumors, as well as the presence of liver metastases. Improved understanding of related genes and molecules will lead to the development of methods of early detection and targeted therapies. For the diagnosis of GCLM, each imaging modality has its relative benefits. There remains no consensus regarding therapeutic options.

CONCLUSIONSEarly detection and characterization of liver metastases is crucial for the prognosis of gastric cancer patients. Multidisciplinary team discussions are required to design optimal treatment strategies, which should be based on the clinicopathological characteristics of each patient.

Humans ; Liver Neoplasms ; diagnosis ; drug therapy ; secondary ; surgery ; Stomach Neoplasms ; complications ; diagnosis ; drug therapy ; surgery

Adult ; Female ; Humans ; Liver Neoplasms ; diagnosis ; surgery ; Neoplasms, Germ Cell and Embryonal ; diagnosis ; surgery ; Sarcoma ; diagnosis ; surgery ; Tomography, X-Ray Computed

No abstract available.
Adult ; Antigens, CD34/metabolism ; Female ; Hemangiosarcoma/diagnosis/*pathology/surgery ; Humans ; Liver Neoplasms/diagnosis/*pathology/surgery

Carcinoma, Hepatocellular ; diagnosis ; surgery ; therapy ; Hepatectomy ; Humans ; Liver Neoplasms ; diagnosis ; surgery ; therapy

Adolescent ; Adult ; Female ; Humans ; Liver Neoplasms ; diagnosis ; surgery ; Male ; Retrospective Studies ; Sarcoma ; diagnosis ; surgery ; Young Adult

Bile Duct Neoplasms ; diagnosis ; surgery ; Bile Ducts, Intrahepatic ; Cholangiocarcinoma ; diagnosis ; surgery ; Hepatectomy ; Humans ; Liver Transplantation ; Prognosis

No abstract available.
Carcinoma, Hepatocellular/complications/*diagnosis/*surgery ; Humans ; Liver Cirrhosis/complications/*diagnosis/*surgery ; Liver Function Tests ; Liver Neoplasms/complications/*diagnosis/*surgery ; *Postoperative Complications ; Prognosis

OBJECTIVETo investigate the diagnostic and therapeutic approach of solitary necrotic nodule of the liver (SNNL).

METHODSFifteen cases were diagnosed as SNNL from June 1999 to December 2005. The clinical characteristics, imaging findings, diagnosis and treatment were analyzed with related literature retrospectively.

RESULTSThe patients manifested abdominal pain and discomfort in 7 cases (46.7%), fever in 1 case (6.7%), debilitation in 1 case (6.7%). Lesions were screened as hypoechogenic patterns in B ultrasound, and CT scan confirmed that the lesion appeared slightly hypodense compared with the normal liver parenchyma without detectable enhanced graphic phases. No significant enhancement was on dynamic magnetic resonance imaging study. All of the nodules demonstrated hypointense and isointense signal relative to parenchyma of liver on both T1 and T2-weighted images. Histologically, the lesion composed mainly of coagulative necrosis with a homogeneous periphery, and the central zone had a rough patchy appearance with cellular debris. The coagulative necrosis was surrounded by a thin boundary of collagen fibers with scanty mononuclear, lymphocyte, plasmocyte inflammatory cells and elastic fibers. Preoperative laboratory examinations showed hepatic function slightly abnormal in 3 patients, and AFP level was normal in all patients. Diagnosis of SNNL was established in 4 cases (26.7%) preoperatively. All patients underwent liver resection with no recurrence within 3 months to 6 years follow-up.

CONCLUSIONSPreoperative diagnosis of SNNL can be established via comprehensive analysis of clinical characteristics and imaging findings. Liver resection is the optimal therapeutic approach.

Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Liver ; pathology ; surgery ; Liver Neoplasms ; diagnosis ; surgery ; Male ; Middle Aged ; Necrosis ; Retrospective Studies

Colorectal cancer is one of the most common malignancies in human, and colorectal liver metastasis (CLM) is one of the most common leading causes of death in these patients. In recent years, along with the update of diagnosis and treatment concept and advancement of operative technique, more and more patients with CLM get surgical treatment opportunities and the outcomes are improved. In clinical practice of CLM, depending on evidence-based medicine, standardized diagnosis and treatment is particularly important, which includes diagnosis and treatment by multidisciplinary team, accurate evaluation of the resectability of CLM, standardized surgical resection and essential comprehensive treatment.
Colorectal Neoplasms ; pathology ; Evidence-Based Medicine ; Hepatectomy ; Humans ; Liver Neoplasms ; diagnosis ; secondary ; surgery ; therapy ; Prognosis