4.Current treatment and progress of hepatocellular carcinoma with portal vein tumor thrombus.
Lei LI ; Zhongchao LI ; Hong LU ; Lei ZHAO ; Xuetao SHI
Chinese Journal of Surgery 2015;53(6):468-471
Portal venous tumor emboli is one of the important factors that affect the prognosis of patients with hepatocellular carcinoma (HCC). There are different characters of surgery, interventional therapy, radiation therapy, treatment of local damage, targeted therapy in the treatment of portal venous tumor emboli, but the effects are not ideal. Scholars at home and abroad are exploring a variety of treatment patterns in the treatment of portal venous tumor emboli, to achieve better effect.Predominantly surgical comprehensive treatment can excision of tumor and tumor emboli, improve liver function, improve the quality of survival, prolong survival time. But the operation risk is big. Mainly non-surgical treatment has advantages of little trauma, less risk, and better local control of tumor emboli. But the efficiency, effect, alleviate period is ineffective. Therefore, the best treatment mode should be explored according to the different tumor emboli parting.
Carcinoma, Hepatocellular
;
complications
;
surgery
;
Humans
;
Liver Neoplasms
;
complications
;
surgery
;
Neoplastic Cells, Circulating
;
Portal Vein
;
Prognosis
;
Thrombosis
;
complications
;
surgery
5.Does Liver Resection Provide Long-Term Survival Benefits for Breast Cancer Patients with Liver Metastasis? A Question Yet to Be Answered.
Yonsei Medical Journal 2015;56(1):309-310
No abstract available.
Breast Neoplasms/*complications/*surgery
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Female
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Humans
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Liver Neoplasms/*secondary/*surgery
;
Male
6.Current status and progress in gastric cancer with liver metastasis.
Chinese Medical Journal 2011;124(3):445-456
OBJECTIVEThis review discusses the current status and progress in studies on gastric cancer with liver metastasis (GCLM), involving the routes, subtypes, and prognosis of GCLM; the genes and molecules associated with metastasis; the feasibility and value of each imaging modality; and current treatment options.
DATA SOURCESThe data used in this review were mainly from Medline and PubMed published in English from 2005 to August 2010. The search terms were "gastric cancer" and "liver metastasis".
STUDY SELECTIONArticles regarding the characteristics, diagnostic modalities, and various therapeutic options of GCLM were selected.
RESULTSThe prognosis of GCLM is influenced by the clinicopathological characteristics of primary tumors, as well as the presence of liver metastases. Improved understanding of related genes and molecules will lead to the development of methods of early detection and targeted therapies. For the diagnosis of GCLM, each imaging modality has its relative benefits. There remains no consensus regarding therapeutic options.
CONCLUSIONSEarly detection and characterization of liver metastases is crucial for the prognosis of gastric cancer patients. Multidisciplinary team discussions are required to design optimal treatment strategies, which should be based on the clinicopathological characteristics of each patient.
Humans ; Liver Neoplasms ; diagnosis ; drug therapy ; secondary ; surgery ; Stomach Neoplasms ; complications ; diagnosis ; drug therapy ; surgery
7.Current status of laparoscopic liver resection for hepatocellular carcinoma.
Hanisah GURO ; Jai Young CHO ; Ho Seong HAN ; Yoo Seok YOON ; YoungRok CHOI ; Mohan PERIYASAMY
Clinical and Molecular Hepatology 2016;22(2):212-218
Laparoscopic liver resection (LLR) is becoming widely accepted for the treatment of hepatocellular carcinoma (HCC). Laparoscopic left lateral sectionectomy and minor laparoscopic liver resection are now considered standard approaches, especially for tumors located in the anterolateral segments of the liver. Laparoscopic left lateral sectionectomy in adult donors is also gaining acceptance for child liver transplantation in many centers. Major LLRs, including left hepatectomy and right hepatectomy, have been recently attempted. Laparoscopic donor hepatectomy is becoming more popular owing to increasing demand from young living donors who appreciate its minimal invasiveness and excellent cosmetic outcomes. Several centers have performed total laparoscopic donor right hepatectomy in adult-to-adult living donor liver transplantation. Many meta-analyses have shown that LLR is better than open liver resection in terms of short-term outcomes, principally cosmetic outcomes. Although no randomized control trials have compared LLR with open liver resection, the long-term oncologic outcomes were similar for both procedures in recent case-matched studies.
Carcinoma, Hepatocellular/complications/pathology/*surgery
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Humans
;
Laparoscopy
;
Liver Cirrhosis/complications
;
Liver Neoplasms/pathology/*surgery
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Neoplasm Recurrence, Local
;
Prognosis
8.Current status of laparoscopic liver resection for hepatocellular carcinoma.
Hanisah GURO ; Jai Young CHO ; Ho Seong HAN ; Yoo Seok YOON ; YoungRok CHOI ; Mohan PERIYASAMY
Clinical and Molecular Hepatology 2016;22(2):212-218
Laparoscopic liver resection (LLR) is becoming widely accepted for the treatment of hepatocellular carcinoma (HCC). Laparoscopic left lateral sectionectomy and minor laparoscopic liver resection are now considered standard approaches, especially for tumors located in the anterolateral segments of the liver. Laparoscopic left lateral sectionectomy in adult donors is also gaining acceptance for child liver transplantation in many centers. Major LLRs, including left hepatectomy and right hepatectomy, have been recently attempted. Laparoscopic donor hepatectomy is becoming more popular owing to increasing demand from young living donors who appreciate its minimal invasiveness and excellent cosmetic outcomes. Several centers have performed total laparoscopic donor right hepatectomy in adult-to-adult living donor liver transplantation. Many meta-analyses have shown that LLR is better than open liver resection in terms of short-term outcomes, principally cosmetic outcomes. Although no randomized control trials have compared LLR with open liver resection, the long-term oncologic outcomes were similar for both procedures in recent case-matched studies.
Carcinoma, Hepatocellular/complications/pathology/*surgery
;
Humans
;
Laparoscopy
;
Liver Cirrhosis/complications
;
Liver Neoplasms/pathology/*surgery
;
Neoplasm Recurrence, Local
;
Prognosis
9.A Case of Primary Adenosquamous Carcinoma of the Liver Presented with Liver Abscess.
Oh Sang KWON ; Hong Sik LEE ; Dong Wook KOH ; Young Jig CHO ; Yeon Ho PARK ; Dong Kyu PARK ; Yong Leul OH ; Jae Hong SEO ; Hoon Jai CHUN ; Sun Ho UM ; Sang Woo LEE ; Jai Hyun CHOI ; Chang Duck KIM ; Ho Sang RYU ; Jin Hai HYUN ; Ae Ree KIM ; Yong Sik KIM
The Korean Journal of Internal Medicine 2001;16(4):270-273
Primary adenosquamous carcinoma of the liver is a very rare type of cholangiocarcinoma and is defined as a cancer containing both squamous and adenomatous components in the same lesion. Recently, we experienced a primary adenosquamous carcinoma of the liver presented as liver abscess. A 63-year-old man was presented with a 4-day history of fever and chill. The radiologic study showed a 4 cm-sized, central hypoattenuated mass with peripheral rim enhancement in the left lobe of the liver. Ultrasonography-guided aspiration and biopsy suggested an adenocarcinoma with abscess in the liver. At laparotomy, the tumor occupied the left lobe of the liver and invaded the right diaphragm. An extended left lobectomy and a partial excision of the involved diaphragm were done. Grossly, the tumor was 6x5x5 cm in size and had an eccentric necrosis. Microscopically, the tumor was composed of adenocarcinoma and squamous cell carcinoma with a transitional area.
Carcinoma, Adenosquamous/*complications/pathology/surgery
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Case Report
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Human
;
Liver Abscess/*etiology
;
Liver Neoplasms/*complications/pathology/surgery
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Male
;
Middle Age
10.Surgical intervention of hepatocellular carcinoma with bile duct thrombi.
Shu-you PENG ; Jian-wei WANG ; Ying-bin LIU ; Xiu-jun CAI ; Yi-ping MOU ; Yu-lian WU ; He-qing FANG ; Cheng-hong PENG
Chinese Journal of Surgery 2003;41(3):169-171
OBJECTIVESTo summarize the experience of surgical intervention for hepatocellular carcinoma (HCC) with bile duct thrombi (BDT), and to evaluate the influence on prognosis.
METHODSFrom 1994 to 2002, 15 patients with HCC and BDT who underwent surgical intervention were retrospectively analyzed.
RESULTSThe operative procedures included hepatectomy with removal of BDT (n = 7), hepatectomy combined with extrahepatic bile duct resection (n = 4), thrombectomy through choledochotomy (n = 3), and piggy-back orthotopic liver transplantation (n = 1). The 1- and 3-year survival rates were 73.3% and 40%, respectively. Two patients survived over 5 year. The survival rate of patients with portal vein invasion was significantly lower than that of patients without portal vein invasion (P < 0.05).
CONCLUSIONSSurgical intervention was effective for patients with HCC and BDT. Operation after recurrence can prolong the survival time. Liver transplantation is a new operative procedure worthy of study.
Adult ; Aged ; Bile Duct Neoplasms ; surgery ; Carcinoma, Hepatocellular ; complications ; surgery ; Female ; Humans ; Liver Neoplasms ; complications ; surgery ; Liver Transplantation ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Thrombosis ; surgery