1.A Case of Primary Hepatic Leiomyosarcoma with Intrahepatic and Abdominal Subcutaneous Metastasis in Behcet's Disease.
Ki Min KWON ; Byoung Kuk JANG ; Woo Jin CHUNG ; Kyung Sik PARK ; Kwang Bum CHO ; Jae Seok HWANG ; Koo Jeong KANG ; Yu Na KANG ; Jung Hyeok KWON
The Korean Journal of Hepatology 2005;11(4):386-391
Primary hepatic leiomyosarcoma is a very rare tumor of the liver and primary hepatic leiomyosarcoma with Behcet's disease has not been reported previously. Behcet's disease is a multisystem disorder presenting with recurrent oral and genital ulcerations as well as ocular lesions; it has rarely been reported in association with malignant disease. We report a case of primary hepatic leiomyosarcoma with intrahepatic and abdominal subcutaneous metastasis in a patient with Behcet's disease; this is the first report of these findings in Korea.
Abdominal Neoplasms/diagnosis/*secondary
;
*Abdominal Wall
;
Adult
;
Behcet Syndrome/*complications
;
Female
;
Humans
;
Leiomyosarcoma/*complications/diagnosis/*secondary
;
Liver Neoplasms/*complications/diagnosis/*secondary
;
*Subcutaneous Tissue
2.Current status and progress in gastric cancer with liver metastasis.
Chinese Medical Journal 2011;124(3):445-456
OBJECTIVEThis review discusses the current status and progress in studies on gastric cancer with liver metastasis (GCLM), involving the routes, subtypes, and prognosis of GCLM; the genes and molecules associated with metastasis; the feasibility and value of each imaging modality; and current treatment options.
DATA SOURCESThe data used in this review were mainly from Medline and PubMed published in English from 2005 to August 2010. The search terms were "gastric cancer" and "liver metastasis".
STUDY SELECTIONArticles regarding the characteristics, diagnostic modalities, and various therapeutic options of GCLM were selected.
RESULTSThe prognosis of GCLM is influenced by the clinicopathological characteristics of primary tumors, as well as the presence of liver metastases. Improved understanding of related genes and molecules will lead to the development of methods of early detection and targeted therapies. For the diagnosis of GCLM, each imaging modality has its relative benefits. There remains no consensus regarding therapeutic options.
CONCLUSIONSEarly detection and characterization of liver metastases is crucial for the prognosis of gastric cancer patients. Multidisciplinary team discussions are required to design optimal treatment strategies, which should be based on the clinicopathological characteristics of each patient.
Humans ; Liver Neoplasms ; diagnosis ; drug therapy ; secondary ; surgery ; Stomach Neoplasms ; complications ; diagnosis ; drug therapy ; surgery
3.Pelvic Bone Fractures Mimicking Bone Metastases in a Patient with Hepatitis B Virus-Associated Liver Cirrhosis and Hepatocellular Carcinoma.
Dong Hyeon LEE ; Eun Sun JANG ; Hong Sang OH ; Kwang Hyun CHUNG ; Eun Hyo JIN ; Eu Jeong KU ; Eun ROH
The Korean Journal of Internal Medicine 2012;27(4):467-469
No abstract available.
Aged
;
Bone Neoplasms/diagnosis/*secondary
;
Carcinoma, Hepatocellular/diagnosis/etiology/*secondary
;
Diagnosis, Differential
;
Female
;
Fractures, Bone/*diagnosis
;
Hepatitis B, Chronic/*complications
;
Humans
;
Liver Cirrhosis/complications
;
*Liver Neoplasms/diagnosis/etiology
;
Osteoporosis/complications
;
Pelvic Bones/*injuries
4.A Case of the Hepatocellular Carcinoma during the Pregnancy and Metastasis to the Left Atrium.
Soon Woo NAM ; Jong Tae BAEK ; Sang Bum KANG ; Dong Soo LEE ; Jin Il KIM ; Se Hyun CHO ; Soo Heon PARK ; Joon Yeol HAN ; Byung Min AHN ; Jae Kwang KIM ; Kyu Won CHUNG
The Korean Journal of Hepatology 2005;11(4):381-385
A 28-year-old female with a pregnant state of 29th gestational week was admitted because of nausea and vomiting. MRI showed a huge hepatocellular carcinoma. At the 36th gestational week, a normal delivery was done. Surgery of hepatocellular carcinoma was done at 20 days after delivery. After 22 months from the operation, pulmonary metastasis was found and resection of lung mass was done. About 3 years after resection, a low attenuating nodule was detected in the left atrial chamber of heart. We report a case of hepatocellular carcinoma with metastatic lesions to lung and heart in a pregnant woman.
Adult
;
Carcinoma, Hepatocellular/diagnosis/*secondary/surgery
;
Female
;
Heart Atria
;
Heart Neoplasms/diagnosis/*secondary
;
Humans
;
Infant, Newborn
;
Liver Neoplasms/diagnosis/*pathology/surgery
;
Lung Neoplasms/diagnosis/secondary
;
Pregnancy
;
*Pregnancy Complications, Neoplastic/diagnosis
5.A case of primary hepatic epithelioid hemangioendothelioma with spontaneous rupture.
Geum Ha KIM ; Yun Soo KIM ; Hyun Ok KIM ; Kil Hyun KIM ; Young Kul HUNG ; Dong Hae JUNG ; Jeong Ho KIM ; Oh Sang KWON ; Duck Joo CHOI ; Ju Hyun KIM
The Korean Journal of Hepatology 2009;15(4):510-516
Primary hepatic epithelioid hemangioendothelioma is a rare neoplasm of endothelial origin. The clinical manifestations are nonspecific, ranging from complete absence of symptoms to hepatic failure and death. Spontaneous rupture of a hepatic epithelioid hemangioendothelioma is an extremely rare presentation. We present a case of primary hepatic epithelioid hemangioendothelioma in a 65-year-old male patient with alcoholic liver cirrhosis. He was hospitalized due to epigastric pain and multiple liver masses on abdominal ultrasound. Dynamic liver CT imaging revealed multiple peripheral nodular enhanced mass lesions with delayed centripetal enhancement, and the adjacent collection of high-attenuation fluid along the liver capsule. Abdominal tapping revealed blood in the peritoneal cavity. Primary hepatic epithelioid hemangioendothelioma with spontaneous rupture was finally diagnosed based on a histopathologic examination revealing positive immunohistochemical staining for CD34.
Antigens, CD34/metabolism
;
Bone Neoplasms/diagnosis/secondary
;
Diagnosis, Differential
;
Hemangioendothelioma, Epithelioid/*diagnosis/pathology/ultrasonography
;
Humans
;
Liver Cirrhosis, Alcoholic/complications/diagnosis
;
Liver Neoplasms/*diagnosis/pathology/ultrasonography
;
Male
;
Pancreatic Neoplasms/diagnosis/secondary
;
Rupture, Spontaneous
;
Tomography, X-Ray Computed
7.Extrahepatic Metastasis of Hepatocellular Carcinoma to the Nasal Cavity Manifested as Massive Epistaxis: A Case Report.
Sung Jae YOO ; Jae Hee CHEON ; Sang Won LEE ; Yoo Seok JUNG ; Sang Hyun LEE ; Joong Won PARK ; Eun Kyoung HONG ; Chang Min KIM
The Korean Journal of Hepatology 2004;10(3):228-232
Extrahepatic metastasis of hepatocellular carcinoma (HCC) is not infrequently found during the later stage, regarding that the autopsy report described its prevalence to be up to 50%. The most frequent sites are known to be the abdominal lymph nodes, lung and bone. However, metastasis to the nasal cavity and paranasal sinuses has been seldom reported, and to out knowledge, there is no Korean report describing extrahepatic metastasis of HCC to these sites. Recently we experienced a case of extrahepatic metastasis of HCC to the nasal cavity in a 50 year-old man with massive epistaxis refractory to conservative treatment. He was found to have a mass of soft tissue attenuation occupying the right nasal cavity at CT, which was biopsy-proven as metastatic HCC. Epistaxis was successfully treated by transcatheter arterial embolization.
Carcinoma, Hepatocellular/*secondary
;
English Abstract
;
Epistaxis/*etiology
;
Humans
;
Liver Neoplasms/*pathology
;
Male
;
Middle Aged
;
*Nasal Cavity
;
Nose Neoplasms/complications/diagnosis/*secondary
8.A Case of Fulminant Hepatic Failure Secondary to Hepatic Metastasis of Small Cell Lung Carcinoma.
Young Tae HWANG ; Jung Woo SHIN ; Jun Ho LEE ; Dae Sung HWANG ; Jun Bum EUM ; Hye Jeong CHOI ; Neung Hwa PARK
The Korean Journal of Hepatology 2007;13(4):565-570
Although liver metastasis is commonly found in cancer patients, fulminant hepatic failure secondary to diffuse cancer infiltration into the liver is rare. Liver metastasis-induced fulminant hepatic failure has been reported in patients with primary cancer of the gastrointestinal tract, breast and uroepithelium, and in patients with melanoma and hematologic malignancy. Small cell lung cancer is so highly invasive that hepatic metastasis is common, but rapid progression to fulminant hepatic failure is extremely rare. We report here on a case of a patient who died because of rapid progression to fulminant hepatic failure as a result of hepatic metastasis of small cell lung carcinoma.
Aged
;
Carcinoma, Small Cell/complications/pathology/*secondary
;
Female
;
Humans
;
Liver Failure, Acute/diagnosis/*etiology
;
Liver Neoplasms/complications/pathology/*secondary
;
Lung Neoplasms/complications/*pathology
;
Neoplasm Invasiveness
;
Tomography, X-Ray Computed
9.A Case of Spontaneous Regression of Hepatocellular Carcinoma with Multiple Lung Metastases.
Jin Hee HONG ; Dong Dae SEO ; Tae Joo JEON ; Tae Hoon OH ; Won Chang SHIN ; Won Choong CHOI ; Hyun Sun CHO
The Korean Journal of Gastroenterology 2010;55(2):133-138
Spontaneous regression of hepatocellular carcinoma (HCC) is extremely rare. We report a case of 67-year-old man having HBV-associated HCC with multiple lung metastases which regressed spontaneously. The patient had single liver mass and received surgical resection. The mass was confirmed as HCC histopathologically. Nine years after surgical resection, a 3.3 cm sized recurred HCC was detected on the resection margin in CT scan. Transarterial chemoembolization (TACE) was performed 3 times, and lung metastases developed thereafter. The patient received 2 more sessions of TACE, however, metastatic lung nodules were in progress very rapidly. We decided to stop TACE and followed the patient regularly without any anti-cancer treatment. Nine months after development of lung metastasis, the size and number of metastatic lung nodules decreased and were not detected anymore after 14 months. Serum alpha-fetoprotein levels also decreased to normal range and no viable tumor was noted in the liver. The patient is still alive 12 years after the first diagnosis of HCC and 16 months after lung metastasis developed.
Aged
;
Carcinoma, Hepatocellular/*pathology/secondary/therapy
;
Chemoembolization, Therapeutic
;
Hepatitis B, Chronic/complications/diagnosis
;
Humans
;
Liver Neoplasms/complications/*pathology/therapy
;
Lung Neoplasms/*diagnosis/radiography/secondary
;
Male
;
Neoplasm Regression, Spontaneous
;
Neoplasm Staging
;
Tomography, X-Ray Computed
;
alpha-Fetoproteins/analysis
10.Hepatocellular Carcinoma with Metastasis to the Cavernous Sinus of Skull Base Causing Ptosis.
Sang Jung KIM ; Hyung Joon KIM ; Hyun Woong LEE ; Chang Hwan CHOI ; Jung Uk KIM ; Jae Hyuk DO ; Jae Kyu KIM ; Sae Kyung CHANG
The Korean Journal of Gastroenterology 2008;52(6):389-393
The cavernous sinus of skull base is a extremely rare metastastatic site for hepatocellular carcinoma (HCC). A 51-year-old man was diagnosed with HCC by liver biopsy and palliative radiotherapy on HCC including main portal vein was performed. One month later, he was admitted due to sudden onset ptosis. Neurologic findings were normal except for abnormal movement of right eye, and it raised the possibility of abnormality in the right occulomotor, trochlear and the abducens nerves. Contrast-enhanced CT scan of brain showed a mass with homogeneous enhancement involving the right cavernous sinus. T2-weighted axial MR images demonstrated a homogeneous mass with intermediate signal intensity, and contrast-enhanced axial T1-weighted MR images demonstrated a mass with homogeneous enhancement in the right cavernous sinus. We describe a case of HCC metastasis to the cavernous sinus with symptoms of ptosis and disturbance of right eyeball movement.
Blepharoptosis/*etiology/pathology
;
Carcinoma, Hepatocellular/complications/*diagnosis/*secondary
;
Cavernous Sinus/*pathology
;
Humans
;
Liver Neoplasms/complications/*pathology
;
Male
;
Middle Aged
;
Ophthalmoplegia/pathology
;
Skull Base Neoplasms/diagnosis/*secondary
;
Tomography, X-Ray Computed