2.A case of primary hepatic actinomycosis.
Jeong Deuk LEE ; Pan Gyu KIM ; Hyeon Mi JO ; Doo Ho PARK
Journal of Korean Medical Science 1993;8(5):385-389
Actinomycosis is a chronic suppurative and granulomatous disease characterized histologically by sulfur granules with extensive necrosis, fibrosis and sinus formation. Depending on the site of primary infection, actinomycosis is generally classified as cervicofacial, thoracic and abdominal type. The liver is known to be the primary site of infection in 15% with abdominal actinomycosis. The authors have experienced a case of liver abscess in a 24-year-old male. The sono-guided aspiration biopsy revealed findings of infiltration of neutrophils and characteristics sulfur granules by light microscopy. This case was thought to represent an instance of liver actinomycosis. Although there have been a lot of reports on actinomycosis of the liver in other countries, only 3 cases were reported in Korea.
Actinomycosis/*diagnosis/drug therapy
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Adult
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Humans
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Liver Diseases/*diagnosis/drug therapy
;
Male
4.Severe liver injury induced by repeated use of hair dye.
Feng-Qin HOU ; Xiao-Hong LIN ; Yan-Yan YU ; Tai-Ling WANG ; Gui-Qiang WANG
Chinese Medical Journal 2009;122(7):875-877
5.Diagnosis and treatment of lung aspergillosis after liver transplantation.
Qi-yuan LIN ; Yong-heng ZHAO ; Lü-nan YAN ; An-hua HUANG ; Bo LI ; Shi-chun LU ; Yong ZENG ; Tian-fu WEN ; Ji-chun ZHAO ; Nan-sheng CHENG
Chinese Journal of Surgery 2003;41(1):17-18
OBJECTIVETo assess the diagnosis and treatment of invasive lung aspergillosis after liver transplantation.
METHODSRoutine sputum culture was performed. Itraconazole and fluconazole were used to prevent fungal infection prophylactically. Amphyotericin B was only used on aspergillosis. In 54 patients receiving, liver transplantation, 3 patients with lung aspergillosis were reviewed.
RESULTSOf the 3 patients 2 died and 1 recovered.
CONCLUSIONSOver-immunosuppression is a main risk factor for aspergillosis. Amphotericin B is still the best choice for the treatment of aspergillosis and its gradual, interrupted, low concentration administration, cooperated with itraconazole can ease the side effects.
Adult ; Aspergillosis ; diagnosis ; drug therapy ; etiology ; Female ; Humans ; Liver Transplantation ; adverse effects ; Lung Diseases, Fungal ; diagnosis ; drug therapy ; etiology ; Male ; Middle Aged
6.A case report: congenital syphilis-induced multiple organ dysfunction.
Chinese Journal of Pediatrics 2014;52(3):229-230
Biomarkers
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analysis
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Delayed Diagnosis
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Diagnosis, Differential
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Female
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Humans
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Infant, Newborn
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Liver Diseases
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diagnosis
;
drug therapy
;
etiology
;
Liver Function Tests
;
Nephrotic Syndrome
;
diagnosis
;
drug therapy
;
etiology
;
Penicillin G
;
administration & dosage
;
therapeutic use
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Skin Diseases
;
diagnosis
;
drug therapy
;
etiology
;
Syphilis, Congenital
;
complications
;
diagnosis
;
drug therapy
7.Prospect of liver fibrosis.
Chinese Journal of Hepatology 2009;17(1):5-6
8.A case of primary hepatic actinomycosis: an enigmatic inflammatory lesion of the liver.
Yeon Jung HA ; Ji Hyun AN ; Ju Hyun SHIM ; Eun Sil YU ; Jong Jae KIM ; Tae Yong HA ; Han Chu LEE
Clinical and Molecular Hepatology 2015;21(1):80-84
Primary hepatic actinomycosis is one of the chronic abscess-forming infections of the liver. Accurate diagnosis is frequently delayed due to its indolent course and nonspecific clinical and radiological manifestations. We report a case of a 57-year-old man presenting with asymptomatic multiple hepatic masses on follow-up abdominal computed tomography performed 1 year after stomach cancer surgery. Although a percutaneous liver biopsy procedure was conducted twice in order to obtain confirmative pathology, only a nonspecific organizing abscess with plasma cell infiltration was revealed, without identification of any organism in the tissue cultures. Ultimately, actinomycosis was diagnosed following the detection of sulfur granules on open surgical biopsied tissue. This case suggests that primary hepatic actinomycosis should be considered as one of the possible causes for enigmatic inflammatory lesions of the liver.
Actinomycosis/*diagnosis/drug therapy/microbiology
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Anti-Bacterial Agents/therapeutic use
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Biopsy, Needle
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Humans
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Liver Abscess/complications
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Liver Diseases/*diagnosis/microbiology/pathology
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Male
;
Middle Aged
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Tomography, X-Ray Computed
9.Diagnosis and treatment of invasive aspergillosis infection following orthotopic liver transplantation.
Shu-hong YI ; Gui-hua CHEN ; Min-qiang LU ; Yang YANG ; Chang-jie CAI ; Chi XU ; Hua LI ; Gen-shu WANG ; Hui-min YI
Chinese Journal of Surgery 2006;44(13):885-888
OBJECTIVETo explore the treatment and appropriate management of invasive aspergillosis infection following orthotopic liver transplantation.
METHODSThe clinical data of 576 cases who underwent orthotopic liver transplantation consecutively between January 2000 and January 2005 were analyzed retrospectively.
RESULTSThe prevalence of invasive aspergillosis infection was 1.74 (9/576), included 8 cases with pulmonary aspergillosis and 1 case with cerebral aspergillosis. The interval between transplantation and diagnosis were from 10 days to 2 months. Persistent or discontinuous low fever maybe the main clinical presentation after operation. Liposomal amphotericin B (AmBisome) is the mainly treatment for invasive aspergillosis infections, 5 patients were cured and 2 patients developed multi-organ aspergillosis infection died.
CONCLUSIONSThe clinical features of invasive aspergillosis infection following orthotopic liver transplantation were un-typical presentations in the early stage and easy to disseminate. Appropriate modification of immunosuppression therapy and early, high dose and long-term application of antifungal treatment is effective and safe to cure the disease.
Adult ; Aged ; Amphotericin B ; therapeutic use ; Antifungal Agents ; therapeutic use ; Aspergillosis ; diagnosis ; drug therapy ; etiology ; Female ; Humans ; Liver Transplantation ; adverse effects ; Lung Diseases, Fungal ; diagnosis ; drug therapy ; etiology ; Male ; Middle Aged ; Neuroaspergillosis ; diagnosis ; drug therapy ; etiology ; Postoperative Complications ; Retrospective Studies
10.Coexistence of Myxedema Ascites and Tuberculous Peritonitis: a Case Report and Literature Review.
Doo Hyuck LEE ; Kyong Wook KUK ; Suk Bae KIM ; Won Sang YOO
Korean Journal of Medicine 2016;91(2):179-184
Some patients have ascites without having liver disease, so it is important to analyze the cause of these ascites. Tuberculous peritonitis is an infectious disease characterized by lymphocyte-dominant exudative ascites. In contrast, myxedema ascites is a very rare disease characterized by a high serum/ascites albumin gradient (SAAG) with hypothyroidism. We herein report a case involving a 48-year-old woman with both diseases simultaneously. She was hospitalized because of massive ascites, generalized edema, and a puffy face. Hypothyroidism was confirmed by thyroid function tests. Her ascitic fluid had a high SAAG; no other specific findings were identified by cytology, culture, or computed tomography. Three months after initiating drug therapy for the hypothyroidism, the patient's systemic edema improved but the ascites recurred. Accordingly, diagnostic laparoscopy was performed, and tuberculous peritonitis was confirmed. As seen in this case, when myxedema ascites is associated with tuberculous peritonitis, an accurate diagnosis may be challenging.
Ascites*
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Ascitic Fluid
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Communicable Diseases
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Diagnosis
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Drug Therapy
;
Edema
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Female
;
Humans
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Hypothyroidism
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Laparoscopy
;
Liver Diseases
;
Middle Aged
;
Myxedema*
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Peritonitis, Tuberculous*
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Rare Diseases
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Thyroid Function Tests