In recent years, with the development of bone marrow and organ transplantation, cytomegalovirus (CMV) has become a common pathogen threatening patients having undergone organ transplantation. CMV may cause severe pulmonary infection and respiratory failure, leading to the death of patient with CMV pneumonia. CMV infectious pneumonia is characterized by the formation of huge type A eosinophil inclusion bodies in the nucleus and cytoplasm of the infected cells. The susceptible population is often associated with low immune function, and to promote the recovery of autoimmune function is the key point for treatment of CMV pneumonia, and the plasma exchange therapy can reconstruct the autoimmune function and improve the prognosis of patients with CMV pneumonia to a certain extent. Now the experience of 1 patient of severe CMV pneumonia treated by ECMO combined with plasmapheresis is reported.

Septic shock has always been a challenging problem for people,with a high incidence rate and mortality.After decades of development,significant progress has been made in the pathophysiology and clinical aspects of septic shock.The"Surviving Sepsis Campaign"guidelines provide a suitable approach to directing treatment,enabling earlier recognition of septic shock and reducing its mortality rate.However,there are still many challenges,such as refractory septic shock(RSS)and multiple organ failure.Over the past decade,extracorporeal membrane oxygenation(ECMO)technology has been increasingly applied in the treatment of critically ill patients.Whether ECMO can be considered as a salvage treatment for RSS is increasingly being considered.This report presents the experience of successfully treating a patient with RSS using ECMO in our department.For the management of RSS,it is recommended to consider ECMO as a worthwhile option,providing some practical experience for the treatment of RSS with ECMO.