The early diagnosis of breast cancer is crucial for improving the prognosis of patients.Some new diagnostic techniques can improve the early diagnosis rate.Studies show that microRNA,proteins in salivary,urinary polyamines could be used as novel tumor markers,with high sensitivities and specificities.With the help of optical technology and computers,the traditional diagnostic imaging technique also make a great breakthrough.Currently,image-guided minimally invasive biopsy techniques such as core needle biopsy and vacuum assisted biopsy have the advantages of accuracy,economy and little trauma,and can provide more samples,which have been widely applied in clinical practice.

Objective To compare the value of liquid-based preparations versus conventional smears in the diagnosis of non-thyroid neck masses from fine needle aspiration. Methods The two different methods were compared by the smear quality and the diagnostic accuracy for the aspiration samples of non-thyroid neck masses of 400 patients. Results The unsatisfactory rate for LBP was lower than that for CS (13.0% vs. 16.0%, P < 0.05). The sensitivity was 94.6% for LBP and 92.9% for CS, and the accuracy was 96.8% for LBP and 95.0% for CS. In the aspect of smear quality, LBP had advantages of quantity of cells, with clear background and easily identifiable cell morphology. Conclusions LBP has more advantages than CS in the identification of non-thyroid neck masses, especially for cervical nodal enlargement. But it has no marked advantages in the diagnosis of salivary gland lesions.

Objective To explore the value of DNA-image cytometry (DNA-ICM) in diagnosis of lung cancer.Methods 532 cases of bronchoalveolar lavage fluid (BALF) and (or) bronchial brushing cytology (216 cases from lung cancer patients and 209 cases from benign lung disease patients) were detected by DNA-ICM and liquid-based cytology (LBC), respectively.The sensitivity and specificity of the two methods were compared.Results The sensitivity and specificity of DNA-ICM were 69.2%and 100.0%, and which of LBC were 46.7% and 97.9%, respectively.The sensitivity of DNA-ICM was significantly higher than that of LBC method in the diagnosis of lung cancer (P<0.05).The sensitivity and specificity of DNA-ICM of BALF were 71.9% and 100.0%, while those of LBC were 48.2% and 98.5%.The sensitivity and specificity of DNA-ICM of bronchial brushing cytology were 62.8% and 100.0%, while those of LBC were 43.0% and 95.3%.The sensitivity of DNA-ICM of BALF and bronchial brushing cytology were higher than that of LBC method ( P<0.05).There were 107 patients who underwent BALF and bronchial brushing cytology simultaneously, the sensitivity of DNA-ICM of BALF was higher than that of bronchial brushing cytology ( P <0.05).Among different histologic types of the lung cancers, the sensitivity of squamous carcinoma was higher that of adenocarcinoma.Conclusions DNA-ICM has great application value in the diagnosis of lung cancer.DNA-ICM in combination with LBC can increase the detection rate of lung cancer. DNA-ICM of BALF is worthy of application in clinical practice.

Objective To explore the value of DNA-image cytometry (DNA-ICM) in diagnosis of lung cancer.Methods 532 cases of bronchoalveolar lavage fluid (BALF) and (or) bronchial brushing cytology (216 cases from lung cancer patients and 209 cases from benign lung disease patients) were detected by DNA-ICM and liquid-based cytology (LBC), respectively.The sensitivity and specificity of the two methods were compared.Results The sensitivity and specificity of DNA-ICM were 69.2%and 100.0%, and which of LBC were 46.7% and 97.9%, respectively.The sensitivity of DNA-ICM was significantly higher than that of LBC method in the diagnosis of lung cancer (P<0.05).The sensitivity and specificity of DNA-ICM of BALF were 71.9% and 100.0%, while those of LBC were 48.2% and 98.5%.The sensitivity and specificity of DNA-ICM of bronchial brushing cytology were 62.8% and 100.0%, while those of LBC were 43.0% and 95.3%.The sensitivity of DNA-ICM of BALF and bronchial brushing cytology were higher than that of LBC method ( P<0.05).There were 107 patients who underwent BALF and bronchial brushing cytology simultaneously, the sensitivity of DNA-ICM of BALF was higher than that of bronchial brushing cytology ( P <0.05).Among different histologic types of the lung cancers, the sensitivity of squamous carcinoma was higher that of adenocarcinoma.Conclusions DNA-ICM has great application value in the diagnosis of lung cancer.DNA-ICM in combination with LBC can increase the detection rate of lung cancer. DNA-ICM of BALF is worthy of application in clinical practice.

Objective To summarize seven-year experience in therapy for acute aortic syndrome.Methods Between May 2009 and June 2016,103 patients(75 males and 28 females)diagnosed as acute aortic syndrome underwent operation. The mean age was(43.13 ±15.07)years(20 -79 years).We applied hypothermic circulatory arrest and selective antegrade cerebral perfusion to achieve organic protection.92 patients underwent Sun's procedure.Bentall procedure was performed on 63 patients.9 patients accepted aortic valve repair or root plasty.Mitral valve was replaced in 5 patients.Right coronary artery bypass grafting was carried out on 3 patients.Results Mean cardiopulmonary bypass time was(231.7 ±55.9)min, and cross-clamp time was(138.1 ±31.3)min.Selective cerebral perfusion time was(31.0 ±6.8)min.9 patients died within postoperative 30-days.Conclusion Despite of progression of treatment on acute aortic syndrome, further researches are still required for severe complications and strategies of therapy.

Objective:To explore the correlation between lateral violence, leadership empowering, psychological capital and work alienation among nurses in Oncology Department.Methods:From July to September 2022, a survey was conducted on 327 nurses of Oncology Department in Jiangsu Province using the Nurse Lateral Violence Scale, Chinese version of Empowering Leadership Scale, Chinese version of Psychological Capital Questionnaire and Nurse Work Alienation Questionnaire. The PROCESS program was used to analyze the moderated mediation model.Results:The lateral violence of nurses in Oncology Department had a positive predictive effect on work alienation, and the difference was statistically significant (β=0.339, P<0.01) . Leadership empowering had a partial mediating effect on the correlation between lateral violence and work alienation with a statistical difference, the effect value was 0.071, accounting for 20.94% of the total effect. Psychological capital had a moderating effect on the second half of the mediating effect of leadership empowering, and the difference was statistically significant (β=-0.360, P<0.01) , and the impact of lateral violence on work alienation increased with the increase of psychological capital level. Conclusions:The lateral violence among nurses in Oncology Department can affect work alienation through leadership empowering. The mediating model of psychological capital regulating the correlation between leadership empowering and work alienation is established.

Objective:To develop the Sexual Health Education Needs Assessment Scale for Breast Cancer Patients and test its reliability and validity.Methods:Guided by Maslow's hierarchy of needs theory and knowledge, belief, and practice theory, an initial scale was formed through literature review, semi-structured interviews and Delphi expert consultation. Through cognitive interviews with 9 patients, the scale was further revised and improved to form a clinical trial version. From December 2021 to September 2022, 397 breast cancer patients from 9 ClassⅢ hospitals in 6 provinces, municipalities and autonomous regions were selected by convenience sampling to conduct a questionnaire survey, test the reliability and validity of the scale and grade it.Results:The Sexual Health Education Needs Assessment Scale for Breast Cancer Patients included four dimensions and 32 items in total. Exploratory factor analysis extracted a total of four common factors, with a cumulative variance contribution rate of 72.258%. The content validity index of the scale was 0.865, and the content validity index of each item was 0.929 to 1.000. The correlation coefficients between each dimension of the scale and the total scale were 0.789 to 0.956, and the correlation coefficients between dimensions were 0.635 to 0.863. The Cronbach's α coefficient of the total scale was 0.979, and the Cronbach's α coefficients of each dimension were 0.897 to 0.969. The half reliability of the total scale was 0.941, and the half reliability of each dimension was 0.851 to 0.946. The total score of the scale was 32 to 160, with 32 to 77 being at a low level, 78 to 117 being at a medium level, and 118 to 160 being at a high level.Conclusions:The developed Sexual Health Education Needs Assessment Scale for Breast Cancer Patients has good reliability and validity, and is suitable for breast cancer patients' sexual health education needs assessment.