Objective To determine the effects of early taste stimulation care in comatose patients with severe traumatic brain injury (STBI). Methods Sixty patients with severe STBI who had been in coma for more than 6 hours and Glasgow Coma Scale (GCS) scored 5-8,were divided into two groups according to random digit table. The control group received conventional care, while the taste stimulation group received both conventional care and early taste stimulation intervention.They were assessed according to GCS at 10, 20 and 30 days after treatment. Results After the intervention, the GCS scores in the taste stimulation group were higher than those of the control group after 20 days (10.70±0.48 vs 8.65±0.58, t=2.714, P<0.05) and 30 days (11.70 ± 0.49 vs 9.60 ± 0.57, t=2.792, P<0.05). Conclusions Early taste stimulation care has a certain wake-promoting effect on comatose patients with STBI.

The system construction and work flow of automatic oral drug dispensing system(AODDS) in our hospital are introduced,its' advantages and disadvantages of the application are analyzed.After applying AODDS,drug dispensing speed and accuracy are significantly increased.AODDS is conducive to promote hospital pharmaceutical care and pharmacy quality administration.The application of AODDS in our hospital may be referred for other hospitals to select AODDS.

Objective To investigate the use and application trend of antibiotics in a cancer hospital in Tianjin,so as to provide reference for the rational clinical use of antibiotics.Methods The related data of antibiotics in the hospital from January 2018 to January 2021 were selected,and the utilization rate,defined daily doses(DDDs)of drugs,antibiotics use density(AUD),defined daily cost(DDC)and ranking ratio(B/A)of antibiotics were statistically analyzed.Results In 2018-2021,the annual use of antibiotics,utilization rate of antibiotics and AUD showed a downward trend.The mean annual utilization rate of antibiotics was 22.42％,and the mean annual AUD was 26.79 DDDs/(100 person·d).The top three antibacterial drugs in terms of annual consumption and DDDs were cephalosporins,carbapenems and penicillins.The main antibacterial drugs at all levels were unrestricted.There were 6 antibacterial drugs with DDC＞100.Voriconazole had the highest DDC.The B/A of ciprofloxacin sodium chloride,moxifloxacin tablets,Latoxefin sodium,moxifloxacin sodium chloride was close to or equal t0 1,indicating that the synchronization of these antibacterial drugs was good.Conclusion In 2018-2021,the selection and use of antibiotics in the cancer hospital in Tianjin was reasonable,and the clinical application indicators met the national standards.