Objective By evaluating the publicly published literature on the budget impact analysis(BIA)of medical insurance in China,to investigate the accuracy of BIA prediction,analyze its influencing factors,and provide reference for medical insurance decision-making in China.Methods PubMed,Web of Science,CNKI,Wanfang and VIP Database were used to collect related literature about BIA research.The quality of included literature was quantitatively evaluated by Quality Assessment Scale for Budget Impact Analysis of the Medical Insurance.The accuracy analysis indicator was the ratio of predicted values to actual values of drug sales revenue.The t-test was used for univariate analysis,and the multiple linear regression analysis was used for multivariate analysis.Results A total of 11 articles were ultimately included in the study,with a scale evaluation score of 0.750 3±0.030 9.There were a total of 24 sample values included in the analysis.The results of univariate analysis showed that the literature score had a statistically significant impact on the accuracy of BIA prediction(P＜0.05),and the multivariate analysis showed that the accuracy of BIA prediction was influenced by literature review scores and average annual/course drug costs(F=7.844,P＜0.05).Conclusion The quality of the literature about medical insurance BIA research in China is good,but there are still problems in data citation,analysis content,and presentation of results.The accuracy of prediction is far from satisfaction,and the prediction values are generally higher than the actual values.It is recommended to increase the emphasis on the quality of medical insurance BIA research and strengthen the relevant research on the accuracy of medical insurance BIA.

OBJECTIVE To provide the suggestions for improving t he enthusiasm of the public to report adverse drug reactions （ADRs），promoting pharmaceutical manufacturers to improve the smoothness of ADR reporting channels by the public and the enthusiasm of assuming the main responsibility for drug safety ，and to provide reference for the performance of drug safety supervision by regulatory departments in China. METHODS Taking 180 pharmaceutical manufacturers that had entered the top 1 000 in the world as the objects ，the questionnaire was prepared to investigate the smoothness of ADR reporting channels through 4 channels：contact number ，e-mail，official website and new media （including Wechat and microblog ） of enterprise . The questionnaire involved the establishment of public reporting channels ，the records and the feedback of enterprises. The existing problems were analyzed and suggestions were put forward. RESULTS & CONCLUSIONS More than 70％ of pharmaceutical manufacturers in China had established the channels for reporting ADR by the public ，which were mainly regular channels such as contact numbers and e-mail ，and each channel had the phenomenon that ADR information couldn ’t be reported. More than 60％ of the public channels established by manufactures lacked inquiry and supplement for the miss ing part of th e reported information ； only 24 pharmaceutical manufacturers provided feedback on ADR information ，and the feedback contents were monotonous. gywf2021-11It is suggested that pharmaceutical manufacturers should pay more attention to ADR monitoring among the public ，consider increasing multiple reporting channels while ensuring the smoothness of channels ，strengthen the training of employee ’s information collection ability to improve the quality of information ，timely feed back the ADR information reported by the public ， and increase the feedback content concerned by the public.