Through discussing the traditional medical ethics culture and medical ethics,this paper pointed out the main problems in the teaching practice of medical ethics:it did not well handle the relationship between the inheritance of traditional culture and the absorption of foreign culture;it emphasized too much on the learning of analysis methods and tools of ethical problems but ignored the cultivation of personality and morality;the teaching curriculum of medical ethics is unreasonable.This paper discussed the similarities and differences between medical ethics and traditional ethics culture,gasped the common essence of ethics,and put forward to better improve the teaching of medical ethics through the construction of basic theory system,the settings and perfection of curriculum system,the construction and improvement of the curriculum evaluation system,and the inheritance of traditional medical ethics cultural.

To explore the origin and prevention of myopia from disfunction of internal organs and obsrtuction of channels.According to the research of ancient literature on relationship between internal organs/channels and myopia,and in the combination with research on neuroelectrophysiology,hemorheology molecular biology and clinic study,the feasibility of treatment on myopia from dysfunction of internal organs and obstruction of channels were analyzed.Dysfunction of internal organs and obstruction of channels played an increasingly important role in the occurring and developing of myopia.In the treatment of myopia,the role of internal organs and channels must be emphasized.

Familial spontaneous pneumothorax(FSP) is a specific type of primary spontaneous pneumothorax.FSP means there are more than one individuals develop pneumothorax and is a rare inherited disease.FSP is different from primary spontaneous pneumothorax in several clinical manifestations.So far the genetic basis and inheritance pattern of this disease are not clear.Progress in this field are reviewed here.

Objective To detect the mutant prevention concentration (MPC) of macrolide resistant Streptococcus pneumoniae, to amplify the resistance gene of Streptococcus pneumoniae mutants selected in the mutant selection window (MSW), and to investigate the mechanism in the resistance of Streptococcus pneumoniae to macrolides. Methods The Streptococcus pneumoniae strain ATCC49619 was enriched in broth, and the bacterial concentrations were adjusted to 1010 colony forming units per milliliter. The minimal inhibitory concentration (MIC), MIC for 99 % of input cells (MIC99), provisional MPC (MPCpr), and MPC of roxithromycin and azithromycin for Streptococcus pneumoniae were determined by agar plate dilution method. The ermB and mefA of Streptococcus pneumoniae mutants selected in the MSW were obtained by PCR method and sequencing. Results The MPCs of roxithromycin and azithromycin for ATCC49619 were 0.80 ?g/ml and 0.51 ?g/ml, and the MPC/MIC99 were 5.0 and 3.9. The ermB gene was detected in Streptococcus pneumoniae mutants selected in the MSW. Conclusion Adjustment of the drug dose may limit the enrichment of macrolide-resistant Streptococcus pneumoniae mutant. The mechanism in the resistance of Streptococcus pneumonia to macrolides may be associated with ermB genes carried.

Objective To study the effect of aspirin on cell proliferation of human gastric cancer cell line SGC-7901 and the probab le mechanism involved. Methods Using MTT method, flow cytometr y (FCM),~~~3 H-TdR incorporation a nd electron microscopy, the effect of aspirin on the SGC-7901 of proliferation and related mechanism were studied. Results Results showed that th e growth of SGC -7901 was inhibited by aspirin. The inhibitory rates for growth of SGC-7901 we re positively correlated with the concentration and duration of aspirin in the m edia. ASA could inhibit DNA syntheses. Sub-G_1 pe ak was detected by FCM, and the rate of apoptosis was between 7.8% and (34.4)% . The cell ratios o f S and G_2/M increased, whereas the cell ratio of G_0/G_1 phase decreased (after) treatment and was in a dose-dependent manner. The SGC-7901 cell line exhibited some mor p hologic features of apoptosis, including cell shrinkage, nuclear condensation, D NA fragmentation, and formation of apoptotic bodies under electron microscopy. Conclusions Aspirin inhibited the growth of human gastric cancer ce ll line SGC-7901. The effects of aspirin on the phase of cell cycle and inducing apoptosis may be partially explained as the cytotoxic effects of aspirin.

The porcine reproductive and respiratory syndrome virus (PRRSV) can cause reproductive barriers in breeding pigs and respiratory symptoms in piglets. In this review, we summarize research progress of the infection and replication mechanisms of the PRRSV. We also review the virulence determinants of the PRRSV. All these fundamental studies are important for the control and elimination of the PRRSV.
Animals ; Porcine Reproductive and Respiratory Syndrome ; virology ; Porcine respiratory and reproductive syndrome virus ; genetics ; pathogenicity ; physiology ; Swine ; Virulence ; Virus Replication

Hypertensive renal damage is based on the extent and duration of hypertension, renal damage caused by varying severity. Hypertensive renal damage due to various causes imbalance of vascular active substances, renal arteriosclerosis, so that the abnormal renal hemodynamic, renal ischemia, low specific gravity of urine, low osmotic pressure and urine. The rapidly increasing incidence of hypertensive renal damage has become one of the most important reasons of end stage renal disease (ESRD). Effective treatment of hypertension is limited by poor compliance and significant adverse reaction of antihypertensive drugs. Therefore, some patients have turned to Chinese medicine (CM), hoping that such treatments might improve the efficiency. The author reviews relevant theory and the latest researches, on the basis of combining diseases and syndrome, discusses state and achievement of hypertensive renal damage with Chinese herbal medicines from fundamental and clinical research and action mechanism from standpoints of Chinese herbal compound and herbal effective chemical composition to take future research for important reference.
Antihypertensive Agents ; therapeutic use ; Disease Progression ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Hypertension, Renal ; diagnosis ; drug therapy ; Kidney ; drug effects ; Medicine, Chinese Traditional ; methods

Objective To evaluate the results of surgical treatment for duodenal gastrointestinal stromal tumor (GIST).Methods Between January 2000 and January 2013,33 patients underwent surgical resection of duodenal GIST in Peking University Cancer Hospital,including local resection and pancreatoduodenectomy.Clinical data,surgical outcome and prognosis were reviewed.Results The median survival time is 94 months (range:55-132 months).The 1,3,5-year survival rates are 97％,89％ and 80％,respectively.The 5 year survival rate of patients after pancreatoduodenectomy and local resection is 78％ and 83％,respectively (P =0.091).It shows that tumor size and mitotic count and Fletcher classification influence overall survival.Conclusions When fulfiling proper safe margins,local resection is a reliable and curative option for most duodenal GISTs.

Objective To study the effect of temperature on the emission of tbrmaldehyde trom the blockboard.Methods A 0.25 m3 simulation chamber was used to explore the emission of formaldehyde from blockboard at the temperature of 15,17,19,21, 23,25,27,and 29 ℃,respectively.The relative humidity,the ventilation velocity and the loading factor in simulation chamber was (50?1)%,1.0 L/min,and(1?0.03)m~2/m~3 respectively.Results A hyperbolic logarithm variation in formaldehyde concentration with time in the chamber was observed at different temperatures.Formaldehyde concentration in the chamber increased remarkably once the temperature exceeded 25 C.The chamber stabilization formaldehyde concentration varied with temperature in accordance with an exponent equation of y=0.921 9?0.024 9e~(0.176 4x)(R~2=0.996 9).Conclusion The temperature can greatly influence formaldehyde emission from the blockboards.Higher temperature will facilitate formaldehyde emission from the blockboards.

The intestinal permeability is crucial for human health,and the changes of intestinal permeability may cause variety of diseases,which is widely concerned.This article reviews the latest research progress in the relationship between intestinal permeability and diseases,the main influencing factors of intestinal permeability and its common testing methods,which may provide new ideas for the clinical treatment of related diseases.