Apoptosis ; Brain ; growth & development ; metabolism ; pathology ; Fetal Growth Retardation ; Humans ; Organ Size

Adenosine Triphosphate ; Mouth ; metabolism ; Receptors, Purinergic P2X ; metabolism

Objective To analyze the transformation of the function of research management department in medical institutions based on the knowledge management.Methods The value chain is introduced to portray the functions of research management department, and a survey is employed to collect existing problems in research management.Results Lack of knowledge management is main reason that limits the research development in medical institutions.Conclusions It is very important to re define the strategy for conducting the research in the medical institutions and to improve the knowledge management in those medical institutions.

Objective To discuss the influence of H1N1 influenza on maternal and fetal outcomes and obstetric management. Methods Totally, data were collected on 19 women, affected by H1N1 influenza and admitted to Shengjing Hospital of China Medical University from November 7, 2009 to December 15,2009, and retrospective analysis was performed on the maternal and fetal outcomes. Results Among the 19 cases, three were( 15. 8%, 3/19) in puerperium, who were all mild cases and recovered. Sixteen (84.2%, 16/19)women were diagnosed as H1N1 influenza during pregnancy, among which two in early pregnancy (12. 5%), seven (43. 8%) in mid-term pregnancy and seven (43. 8%) in late pregnancy. According to the severity of H1N1 influenza, six were mild cases (37. 5% ,6/16), two (12. 5% ,2/16)were severe cases and eight (50. 0% ,8/16)were critical. For these 16 pregnant women, thc two cases in early pregnancy (mild cases) were terminated after recovery from H1N1 influenza. Among the seven mid-term cases, four mild and one of the three severe and critical cases delivered till term, and two of the three severe and critical cases were delivered abdominally because of fetal death intrauterine or maternal severe complications at 27 or 23 weeks of gestation. All of the seven late pregnant cases underwent emergent cesarean section due to maternal or fetal reasons, and two fetuses died in the uterus at late pregnancy and five survived including four preterm babies and one full term baby. Altogether, nine cases (56. 3%, 9/16)underwent emergent cesarean section, and six babies born alive and five survived without any symptom of influenza, two women died (10. 5%,2/19) after the operation. Conclusions Pregnant women during late pregnancy infected by H1N1 influenza are susceptible to develop into severe and critical conditions. Termination of the pregnancy in time is effective in both life-saving of the mothers and babies and prevent neonatal infection against H1N1.

OBJECTIVE:To keep abreast of the consumer demand about using drugs and to provide information for the production and marketing business of the pharmaceutics METHODS:To give an account of the present situations of the perceptual consumption and relevant marketing tactics in China and to analyze them RESULTS AND CONCLUSION:We have pointed out the situations of awareness of the perceptual consumption and the marketing tactics in China,which fits in with the perceptual consumption at present

With the development of society and the improvement of people's living standards, the effect of Chinese medicine in treatment and health care is more and more prominent. The herbal decoction pieces are the important part of Chinese medicine,it can be applied directly to clinical treatment and it's also the raw material of Chinese patent medicine. Therefore, the quality of herbal decoction pieces is quite important. The parts of the production of herbal decoction pieces are numerous, and there are possibilities of adverse effects on the quality of the herbal decoction pieces in every part. In this paper, we based on the production chain of herbal decoction pieces, analyzed the main problem that affect the quality of herbal decoction pieces in the part of selection of Chinese herbal medicines, planting, purchasing, processing, packaging, storage and transport, such as the poor quality of seed and seedlings of plant-based Chinese medicines, some plants left their place of origin and have been introduced in the place that is not suitable for this kind of plant, the insufficient growth time and the excessive harmful substances. The purchasers and the accepters lack of professional knowledge and professional ethics. The mechanism of processing is not clear, the standards can not be uniformed, and lack of qualified person in processing, etc. So we suggest: intensify the basic research of key scientific issues. Improve the quality of persons who work in herbal decoction pieces; Establish an "integration" mode of operation in herbal decoction pieces enterprise; Breeding high quality plant resources, establish the large-scale planting basement; Make the packing of herbal decoction pieces standard; Establish the modernization traditional Chinese medicine logistics enterprise.
Chemistry, Pharmaceutical ; economics ; manpower ; standards ; Drug Packaging ; economics ; manpower ; standards ; Drug Storage ; economics ; standards ; Drugs, Chinese Herbal ; chemistry ; standards ; Humans ; Medicine, Chinese Traditional ; economics ; standards ; Quality Control

Acquired Hyperostosis Syndrome ; therapy ; Combined Modality Therapy ; Humans ; Integrative Medicine ; Male ; Middle Aged

The technical structure of a low-cost thermal imaging system (TIM) lunched on a mobile phone was investigated, which consists of a thermal infrared module and mobile phone and application software. The designing strategies and technical factors toward realizing various TIM array performances are interpreted, including sensor cost and Noise Equivalent Temperature Difference (NETD). In the software algorithm, a mechanism for scene-change detection was implemented to optimize the efficiency of non-uniformity correction (NUC). The performance experiments and analysis indicate that the NETD of the system can be smaller than 150 mK when the integration time is larger than 16 frames. Furthermore, a practical application for human temperature monitoring during physical exercise is proposed and interpreted. The measurement results support the feasibility and facility of the system in the medical application.
Algorithms ; Body Temperature ; Cell Phone ; Humans ; Infrared Rays ; Mobile Applications

miRNA is a kind of endogenous non-coding short RNA. Mature miRNA was formed through the process of shearing and transporting after genetic transcription. miRNA exhibits many important biological functions through regulating expression and translation of target mRNAs. Different miRNAs may act as oncogenes or antioncogenes, and have tissue specificity. The progress of the tumorigenesis is usually accompanied by expression-profile changes of miRNAs. MiRNA regulates many tumor biological behaviors such as differentiation, proliferation, apoptosis, invasion, metastasis, and drug resistance of tumors. Furthermore, some miRNAs have clinical significance in predicting prognosis of tumor patients.