1.DEPRESSIVE AND/OR ANXIETY DISORDER IN PATIENTS WITH AWARENESS DURING GENERAL ANESTHESIA
Modern Hospital 2009;9(7):15-17
Objective To reveal the prevalence of depressive and/or anxiety symptom and disorder in patients with awareness during general anesthesia.Methods 10 patients which had the awareness during general anesthesia were selected into AR group (awareness with recall during general anesthesia group).Face-to-face interviews were used in data collection together with the self-completed HAD scale for depressive and/or anxiety symptom screening.Subjects getting a HAD score of 9 and above were further assessed for depressive and/or anxiety disorders with HAMA scales and HAMD scales.Results The difference of common general state of patients, such as age, weigh and the time during operation were all insignificant between two groups (p>0.05).The rate of patients received general anesthesia only in AR group was higher than that in control group(p<0.05).The prevalence of depressive symptom, the prevalence of depressive or anxiety symptom and the prevalence of depressive and anxiety symptom in AR group were higher than that in control group(p<0.05).The prevalence of depressive disorder, the prevalence of depressive or anxiety disorder and the prevalence of depressive and anxiety disorder in AR group were higher than that in control group too(p<0.05).Conclusion There was high prevalence of depressive and/or anxiety symptom and disorder in patients with recall-awareness during general anesthesia.
2.Life Satisfaction between Urban and Rural Middle School Students
Chinese Mental Health Journal 2002;0(10):-
Objective: To compare the differences between urban and rural middle school students on life satisfaction. Methods: 1152 urban and rural middle school students were measured by Multidimensional Students'Life Satisfaction Scale ( MSLSS - CV) . Results: ( 1 ) The urban students had higher scores than their rural counterparts on all the satisfaction dimensions ( mean value differences = 0. 2 - 0. 4. For example, the family satisfaction of urban and rural students were 4. 6?1. 0, 4. 2?1.0 respectively, mean value difference =0. 4; the serf satisfaction of urban and rural students were 4. 6?0. 7 , 4. 4?0. 7 respectively, mean value difference = 0. 2 ) . ( 2 ) The mean values rank (from high to low) of the five dimensions on the satisfaction was family, self, friend, school and living environment in urban students. The mean values rank (from high to low) of the five dimensions on the satisfaction was self, family, friend, school and living environment in rural students. (3 ) The difference between city and countryside had higher explained percentage than popularity on all the satisfaction dimensions. The percents were as follows: 5% , 10% , 4% , 6% , 17% , 11%. Conclusion: There were significant differences on life satisfaction between urban and rural middle school students.
3.Correlations between Self-Esteem and Life Satisfaction in Elementary School Students
Chinese Mental Health Journal 2002;0(11):-
Objective:To explore the correlations between self-esteem and life satisfaction in elementary school students. Methods:494 elementary school students were measured with CSES (Children's Self-Esteem Scale) and BMSLSS (Brief Multidimensional Students' Life Satisfaction Scale). Results: (1) There were significant gender and grade differences on self-esteem in elementary school students. Girls got higher scores(Means were 3.8?0.8?3.8?0.9?3.9?0.8)than boys on achievements, discipline and social morality-help(Means were 3.5?0.9?3.2?0.8?3.6?0.9,F=17.2?47.0?16.6, P
4.Study on The Effects of Chronic Renal Failure on Hearing and Its Mechanism
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To observe the effects of chronic renal failure (CRF)on hearing and investigate its mechanism.[Methods] Twenty-nine male wistar rats were randomly divided into four groups:Ⅰthe normal rats as control for 12 days (n=6); Ⅱrats given adenine(ig) for 12 days (n=8); Ⅲthe normal rats as control for 24 days (n=6);Ⅳ rats given adenine(ig) for 24 days(n=9). The rat model of CRF was produced by being perfused of adenine [300mg/kg]for 12d and 24d. Brain-stem auditory evoked potential(BAEP) was utilized to evaluate the auditory function and renal tissue morphology was observed; Serum sampling was used to determine the content of Cr, BuN. The expression of NOSⅡin the cochlear was measured by immunohistochemical technique.[Results] After adenine given for 12d or 24d, the Cr and BuN were in significant higher level than that in control group. The BAEP thresholds were gradually higher than that in control group, the BAEP delitescence prolonged. Light microscopic observation of renal tissue showed that the degree of fibrosis was gradually higher. Data of immune histochemistry about the cochlear tissue showed that the expressions of NOSⅡ were feebly positive in the cochlear vassal texture, inner-outer hairy cell and helical-ganglion cell, and following functional damage of the kidney, their expressions reinforced gradually, amongst which strongest expression was vassal texture, the next helical-ganglion cell, the last inner-outer hairy cell.[Conclusion]CRF can result in deafness. It is likely concerned with toxic effects of the metabolizable substance, the metabolizable dysfunction of the electrolyte, shortage of trace elements, etc. One of the important mechanisms of the effects of CRF on hearing is the toxic damage of NO to cochlea.
5.Aeromedical research in the U.S.navy
Military Medical Sciences 2016;40(7):587-592
Objective To analyze the statusquo of the United States Naval Aeromedical Research Development in order to explore the medical context for the development of the U .S.naval aviation .Methods The literatures published by NAMRL between 1975 and 2010 were collected and analyzed using TDA software .Results and Conclusion Naval Aerospace Medical Research Laboratory ( NAMRL ) research was fruitful, the quantity of annual research output was irregular, per capita author posting was not high ,and coauthor size was small .Posting information was oriented to internal and main scientific and technological journals while research focused on the aviation selection , physiological effects , cognition, visual function, physical training and standards , and other areas of radiation protection .Aviation medicine had distinct features.The results are of referential value for keeping track of the U .S.Navy aviation medicine.
6.Limited Smith-Petersen approach for Pipkin fractures of types Ⅰ and Ⅱ
Chinese Journal of Orthopaedic Trauma 2016;18(5):428-430
Objective To evaluate the clinical results of limited Smith-Petersen approach in the treatment of posterior dislocation of hip with femoral head fracture (Pipkin fracture of types Ⅰ and Ⅱ).Methods From February 2008 to July 2013,21 patients with Pipkin fracture of types Ⅰ and Ⅱ were treated at our department.They were 16 men and 5 women,with an average age of 39.2 years (range,from 19 to 56 years).The left hip joint was affected in 8 cases and the right in the other 13.The interval between injury and surgery varied from 2 to 7 days (mean,4 days).According to the Pipkin classification,there were 11 cases in type Ⅰ and 10 in type Ⅱ.All the fractures were fixated via the limited Smith-Petersen approach.Results The patients were followed up for 11 to 29 months (mean,17.4 months).All the fractures healed after an average of 15 weeks (from 12 to 19 weeks).According to their Thompson-Epstein scores of clinical and radiological outcomes at the final follow-ups,7 cases were excellent,9 good and 5 fair,giving a rate of excellent to good of 76.2%.Avascular necrosis of the femoral head occurred in 3 cases and osteoarthritis in 2.No infection or limb deep vein thrombosis was observed.Conclusion For Pipkin fractures of types Ⅰ and Ⅱof,limited Smith-Petersen approach can provide satisfactory exposure which leads to reduced soft tissue injury,better reduction and fixation,and fewer complications as well.
7.Elaboration on treatment experience of dampness in Medical Origin and Insights
International Journal of Traditional Chinese Medicine 2016;38(8):677-679
To elaborate the the main thoughts and treatment experience of dampness in Medical Origin and Insights, written by Zhang Yuansu. Dampness-resolving drugs and prescriptions were comprehensively and carefully summarized and analyzed. Strengthening spleen and stomach was viewed as guideline, and Rhizoma Atractylodis Macrocephalae as well as its brilliant combinations, was taken as preferred drug to resolve dampness, with the help of brilliant combinations. Emphasis was laid on the treatment according to patterns, positions and characters of diseases. Medical Origin and Insights, essence collector of Zhang’s thoughts, has enriched and developed basic traditional Chinese medicine theories and practices. Thus, it showed guiding significance on dampness treatments.
8.Effects of Genistein on Epithelium-Mesenchyme Transition of Alveolar Type Ⅱ Cells
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(10):63-66
Objective To investigate the effects of genistein on the epithelium-mesenchyme transition of alveolar type II cells; To discuss its mechanism of improving pulmonary fibrosis. Methods The activity of genistein with different concentrations and TGF-β1 intervention cells after 72 h were determined by CCK-8 method; epithelial and mesenchymal markers as well as the key regulatory factors in the transformation process were determined by RT-PCR; changes of p38 and JNK signaling pathways were determined by Western blot. Results The A549 cells were transformed into fibroblast phenotype stimulated by TGF-β1 for 72 h; mesenchymal markers increased and endothelial marker decreased. The results of RT-PCR indicated that genistein inhibited this phenomenon in a concentration-dependent manner. The results of Western blot showed that, genistein possibly inhibited the epithelial-mesenchymal transition through inhibiting the phosphorylation of p38 and JNK signaling pathways and its downstream transcription factors. Conclusion Genistein has anti-fibrosis effects through inhibiting A549 cells undergoing epithelial-mesenchymal transition.
9.Application of Microperimeter in the Visual Function Evaluation
Journal of Forensic Medicine 2014;(3):194-196
In condition of direct vision on fundus of eye, microperimeter can quantitatively detect the retinal light sensitivity of macular area, and record real time tracking of the eye, automatically analyze the location and stability of fixation. Microperimeter matches fundus image with micro cyclogram point-to-point, thus it achieves the combination of visual function and structure. The characteristics of microperimeter have good relations with subjective vision, so it can be a new method for the accurate vision evaluation and has application potential to assess the visual function in legal medicine. In this ar-ticle, we summarize the principle, method and parameters of microperimeter. Also, the applications of microperimeter in vision assessment are focused in order to provide a reference for the assessment of visual function in the legal medicine.
10.Gegen Qin Lian Tang combined with human amniotic mesenchymal stem cell transplantation for early diabetic retinopathy
Chinese Journal of Tissue Engineering Research 2016;20(19):2824-2830
BACKGROUND:Human amniotic mesenchymal stem cel s have the potential to differentiate into insulin-secreting cel s and have immunomodulatory effects. Additional y, it has been clinical y proved that Gegen Qin Lian Tang can lower blood sugar. OBJECTIVE:To investigate the effects of Gegen Qin Lian Tang combined with human amniotic mesenchymal stem cel transplantation on rat early diabetic retinopathy, by detecting pathological changes, levels of blood indicators and expressions of vascular endothelial growth factor in retinal tissues. METHODS:By intraperitoneal injection of streptozotocin, 42 Wistar rat models with diabetes mel itus were prepared and then randomly divided into model group, human amniotic mesenchymal stem cel transplantation group (cel transplantation group) and combination of human amniotic mesenchymal stem cel s and Gegen Qin Lian Tang group (combination group). At 4 weeks after transplantation, levels of blood sugar and serum insulin in diabetic rats were detected;pathological changes of the retina in diabetic rats were observed by hematoxylin-eosin staining. Besides, expressions of CD45 and vascular endothelial growth factor mRNA were detected using immunohistochemistry staining and RT-PCR technology, respectively. RESULTS AND CONCLUSION:Compared with the model group, the levels of blood glucose and serum insulin in both cel transplantation and combination groups were significantly decreased and increased, respectively, and these changes were even more significant in the combination group (P<0.05). In the model group, the retinal edema could be found, accompanied by structural disorder and irregular cel arrangement, while these retinal lesions were relatively milder in the cel transplantation group and significantly improved in the combination group. In addition, the CD45 expression and in the retina was highest in the model group subsequently fol owed by the cel transplantation group (P<0.05) and lowest in the combination group (P<0.05). Furthermore, compared with the model group, the expression of vascular endothelial growth factor mRNA was also significantly lower in the other two groups, especial y in the combination group (P<0.05). These data show that Gegen Qin Lian Tang combined with human amniotic mesenchymal stem cel transplantation improves the severity of diabetic retinopathy by inhibiting expressions of CD45 and vascular endothelial growth factor in the retinal tissues.