3.Web Resources for Microbial Data
Sun QINGLAN ; Liu LI ; Wu LINHUAN ; Li WEI ; Liu QUANHE ; Zhang JIANYUAN ; Liug DI ; Ma JUNCAI
Genomics, Proteomics & Bioinformatics 2015;(1):69-72
There are multitudes of web resources that are quite useful for the microbial scientific research community. Here, we provide a brief introduction on some of the most notable microbial web resources and an evaluation of them based upon our own user experience.
4.The expression and significance of EGF,TGF-? and EGFR in the natural concrescence course of rats gastric ulcer
Jianping LIU ; Tao BU ; Jianyue BAI ; Xianming HOU ; Zhigeng LI ; Yan HAN ; Quanhe ZONG ; Zhiqiang CHEN ; Bingzhan NIU ;
Chinese Pharmacological Bulletin 2003;0(10):-
AIM To study the epidermal growth factor (EGF) and transforming growth factor ? (TGF ?)and the epidermal growth factor receptor(EGFR)during the course of rats gastric ulcer natural cure expressing and its possible biology meaning. METHODS We injected acetic acid to make the ulcer animal model, location expression characteristic of EGF and TGF ? and EGFR were studied by immunohistochemistry. RESULTS The normal rats stomach mucosa EGF,TGF ? and EGFR all expressed weakly at masculine. EGF and TGF ? was located at cytoplasm,and EGFR expressesed at cytoplasm and cell membrane and the expression position of the three ovrlopped with each other. EGF concentrated mainly on the cervical part of gastric gland, and TGF ? and EGFR, on the cervical and base parts of the gastric gland. Positive 9 expression cells were primarily parietal[FQ(11?46,X-WZ] and neck cells of the stamook muc. For materials taken during the course of ulcer natural recovery, regular ohanges were observed in TGF, TGF ? and EGFR expression. Higher expression was found in ulcer tissunes than in normal tissues, while the expression was not detectable in necrotic tissues and rarely detectable in granlation and scar tissnes. The expression became apparant only during healing and scar stages of ulcer but not in early stage. CONCLUSION ①TGF ?/EGFR autocrine system probably plays a leading role in maintaining rats mucosa completeness under the normal circumstances; ②EGF/EGFR and TGF ?/EGFR autocrine system may have important effect on the differentiation, hyperplasia, moving of cell and restraining the gastric acidity.
5.Short-term effect of arthroscopy repair for hiprotator-cufftear
Xiangyu YIN ; Yi LIU ; Quanhe JIN ; Wenguang LIU ; Qingfeng YIN
Chinese Journal of Orthopaedics 2023;43(23):1593-1600
Objective:To investigate the clinical characteristics of hip rotator-cuff tear, arthroscopic repair techniques, and short-term clinical efficacy.Methods:A retrospective analysis was performed on the patient cohort from our department who underwent arthroscopic repair for hip rotator-cuff tears from September 2019 to May 2021, with a minimum follow-up duration of two years. The sample included 17 subjects, composed of 6 males and 11 females, with a median age of 56 years (interquartile range 49.5-62.5). Notably, 9 patients (53%) reported nocturnal pain, and 10 patients (59%) exhibited a positive hip flexion resistance test. Patients' demographic details, clinical manifestations, radiographic findings, and intraoperative observations were analyzed. Pain amelioration was gauged by the visual analogue scale (VAS) at preoperative, 1 month, 3 months, and 6 months postoperative intervals. Enhancement in hip functionality was assessed by comparing the modified Harris hip score (mHHS), and the International hip outcome tool-12 (iHOT-12) at preoperative, 6 months, 12 months, and 24 months postoperative junctures.Results:All interventions were successfully completed, with an average surgical duration of 91.2±18.3 minutes. The follow-up period averaged 29 months. Every patient presented with a hip rotator-cuff tear, which was corrected using anchor suturing. 10 patients also had concomitant labrum injuries, with 5 cases undergoing labrum repair. The VAS score decreased from preoperative 5.24±1.15 to postoperative 2.29±0.69 at 1 month, 1.77±0.56 at 3 months, and 1.59±0.62 at 6 months ( F=79.31, P<0.001); The mHSS score increased from preoperative 49.59±6.11 to postoperative 81.00±3.89 at 6 months, 81.71±3.41 at 12 months, and 81.94±3.29 at 24 months ( F=232.00, P<0.001); The iHOT-12 score increased from preoperative 42.65±6.04 to postoperative 6 months 66.53±3.43, 12 months 68.12±3.48, and 24 months 69.06±3.53 ( F=150.00, P<0.001). Conclusion:Diagnosing hip rotator-cuff tears necessitates specific physical examinations complemented by high-definition magnetic resonance imaging. Arthroscopic surgery represents a potent treatment modality for hip rotator-cuff injuries, demonstrating substantial short-term clinical efficacy.