Objective To investigate mediate role of coping strategy between stressful life events and negative emotions which anxiety and depression are included.Methods Questionnaires of psychosocial stress survey for groups (PSSG),Simple Coping Style Questionnarire(SCSQ),Selfrating Anxiety Scale (SAS) and Selfrating Depression Scale(SDS) were used to examine 1 764 young servicemen.Results Correlation analysis showed that there existed negative correlations between positive coping and stressful life events,passive coping,anxiety,depression(r=-0.080～-0.304,P＜0.05).And correlation analysis also showed there existed positive correlations among the other variables(r=0.230 ～ 0.756,P＜0.05).There existed partly mediating effect of positive coping,passive coping between stressful life events and negative emotions.The standardized total effect of life events to anxiety was 0.302.Mediating effects of positive coping and passive coping were 0.033,0.044.The standardized total effect of life events to depression was 0.230,mediating effects of positive coping and passive coping were 0.051,0.029.Conclusion Coping strategy is an important mediator between stress and negative emotions such as anxiety and depression.

Objective To investigate the effect and function analysis by sulfentanyl in patients with tongue cancer postoperative analgesia.Methods A total of 74 patients with radical resection of tongue cancer in department of anesthesiology with general anesthesia from our hospital were collected, patients or their families signed consent, according to postoperative self-controlled intravenous analgesia drugs divided into experimental group and control group with 37 cases in each group.Patients in control group were treated by fentanyl self-controlled intravenous analgesia;patients in experimental group were treated by sulfentanyl self-controlled intravenous analgesia, determination of the analgesic effect, sedative effect and the changed of vital signs postoperative 2, 4, 8, 12, 24, 48 h,at the same time recorded complications.Results After operation, at different time points analgesic effect and sedative effect were changed in the two groups, the VAS scored of the experimental group was lower than the control group postoperative 2, 4, 8, 12, 24, 48 h time points, the Ramsay Sedation scored of the experimental group was lower than the control group postoperative 2 h, 4 h, 8 h, 12 h time points ( P <0.05 ); the changed of vital signs and adverse reactions between the two groups had no difference within 48 hours ( P >0.05 ) . Conclusion Sulfentanyl in the treatment of patients with radical resection of tongue cancer the analgesic effect and sedative effect are better than fentanyl, has no effect on the vital signs, and the role is security and exact.

Objective To study the best process of puerarin refined.Methods Results of the research on the selection of dissolved agent, agent and precipitator, and column chromatography of the resin, alumina, silica gel, fly ash and activated carbon were used to study the combined process. Results The average purity of optimization of the three craft products were 99.06052%, 99.22620% and 99.69880%.The yield of average values were 44.180%, 44.438% and 42.642%.Conclusion This study optimized the optimum process is feasible, puerarin purity is more than 99%, the yield is above 40%.

The glucose metabolism pathways including glycolysis and oxidative phosphorylation in vivo.The metabolism of tumor cells depends on glycolysis,which enhances the adaptability of tumor cells to the microenvironment and promotes the proliferation of tumor cells,which is called Warburg effect.Arsenic is one of the chemical pollutants,which is widely distributed in natural environment.International agency for research on cancer (IARC) has made it clear that arsenic and its compounds are carcinogens.However,the mechanism of carcinogenesis induced by arsenic still remains obscure.Recently,researchers have found that Warburg effect plays an important role in the process of arsenic carcinogenesis.In this paper,we have reviewed the definition and function of glycolysis,its relationship with inflammation and tumorigenesis,and the role of Warburg effect in arsenic carcinogenesis.

Objective:To study the clinic effects of Prescription Zhuyun-Ⅲ(ZYⅢ) on early pregnancy women diagnosed as threatened abortion,and its mechanism in immunity and endocrine by determining the changes of serum Th1 and Th2-type cytokines,progesterone(P) and ?-human chorionic gonadotropin(?-HCG).Methods:The treatment group comprised of 30 early pregnancy women diagnosed as threateded abortion as well as deficiency syndrome of deficiency syndrome of Spleen or Kidney diagnosed by TCM,the control group consisted of 20 normal early pregnancy women at similar gestational age.The treatment group was administered with ZYⅢ for 4 weeks.Peripheral blood samples from the above two groups pre-and post-treatment were collected,serum Th1 type cytokine IL-2 and Th2 type cytokine IL-10 were determined by flow-cytometry.Serum P and ?-HCG were determined by ELISA.Results:①The serum IL-2 level and the ratio of IL-2/IL-10 in the treatment group before therapy were significantly higher than the control group(P

To study the relationship between angiotensin converting enzyme(ACE) gene polymorphism and angiotensin converting enzyme activity,the polymerase chain reaction(PCR) was used to detect an insertion/deletion(I/D) polymorphism of ACE gene in its sixteenth intron.The genotype,enzyme coupling spectrophotometry were used to measure serum ACE activity among the three genotypes.Results showed that the Serum ACE activities were (337 6?92 0),(292 7?76 5 )and(243 5?58 9)u/L for genotypes DD,ID and ⅠⅠ respectively.The findings indicate that the ACE gene polymorphism closely associated with serum ACE activity.

Objective To sum up the precaution and treatment of the postoperative complications of the aged patients with cerebral impairments. Methods The clinical data of 96 aged patients with cerebral impairments were reviewed, 76 patients of which had postoperative complications. Results Among the 76 patients with postoperative complications, 24 cases died, and the death rate is 31 7%. 11 patients died of lung failure due to lung infection, 4 patients died of massive bleeding of upper digestive tract, 3 patients died of heart failure, 4 patients died of renal failure and the other 2 patients died of recurrent hematoma. Conclusions The postoperative death rate of the aged patients with acute cerebral impairment is fairly high, and the main death cause is postoperative complications, so we should treat this kind of patients in time and prevent the occurrence of complications.

Titanium & titanium alloy are popular in dentistry as dental material because of their good mechanical properties and extremely good biocompatibility. The bonding strength between the titanium and the resin agent is the decisive factor in evaluating the success of resin-bonded restoration. Appropriate surface treatment on the titanium is an effective way to reinforce the bending strength. The purpose of this review is to summarise the relevant studies and introduce some latest findings.

Objective To analyze the results of blood lipids examination in medical workers,so as to understand the cause of ab-normal blood lipid level and formulate the strategy of health education.Methods 500 cases of hospital workers were enrolled as subjects for the study.Under fasting conditions,the samples of the upper arm vein blood were collected,and the detection of total cholesterol(TC),triglycerides(TG),low-density lipoprotein(LDL),and high density lipoprotein(HDL)of serum were proceed on automated analyzers.The results were analyzed.Results In all the 500 workers,there were 152 cases with hyperlipoidemia,ac-counting for 30.4%.The dyslipidemia rate of male workers was 34.7%,and which of female workers was 24.4%.≤30 age group had the lowest dyslipidemia rate(12.9%),and >45-50 age group had the highest dyslipidemia rate(45.8%).There was signifi-cant difference between them(P <0.01).Conclusion The dyslipidemia rates of workers are different across age and gender.It is helpful for workers to have focused health education to improve their live qualities.

A total of 450 residents from three neighborhood committees of Ba'nan were selected to assess their willingness to accept paid influenza vaccine and the influencing factors.Among them,273(60.7％) were willing to accept paid influenza vaccine.Age,economic status,health,flu recognition and vaccine approval were the major influencing factors of vaccination.