1.A Clinical Research on Intervention in Appendix Inflammatory Mass by Heavenly Cool-inducing Technique Adopted Distant and Neighboring Point Selection
Chinese Journal of Information on Traditional Chinese Medicine 2014;(11):17-19
Objective To study the clinical efficacy and the difference of intervention in appendix inflammatory mass by heavenly cool-inducing technique adopted distant and neighboring point selection. Methods Eighty patients of the appendix inflammatory mass with toxic heat syndrome were randomly divided into control group, distant point selection group, neighboring point selection group, and combined group, 20 cases in each group. The control group adopted the conventional western medicine treatment. On the basis of control group, the rest 3 acupuncture groups adopted the heavenly cool-inducing technique for 14 d. The distant point selection group chose Hegu point and Lanwei point;the neighboring point selection group chose Ashi point and Tianshu point (right);the combined group put them together. The longest diameter and three-dimensional volume of inflammatory mass were determined before and after treatment. The serum levels of white blood cells, C-reactive protein were determined at the same time, and then the clinical effective was estimated. Results The longest diameter, three-dimensional volume of inflammatory mass, the serum levels of white blood cells, and C-reactive protein of patients in 4 groups were reduced after treatment. The above indicators in patients of 3 acupuncture groups were lower than the ones in control group, the indicators in combined group were the lowest (P<0.05, P<0.01), and there was no difference between distant and neighboring point selection groups (P>0.05). The invalid number of cases in 3 acupuncture groups were fewer than the one in control group, and the indicators in combined group were fewest (P<0.05, P<0.01), with no difference between distant and neighboring point selection groups (P>0.05). Conclusion There is obvious therapeutic efficacy of heavenly cool-inducing technique to appendix inflammatory mass, while the combination of distant and neighboring point selection is better than the single methods.
2.Progress of molecular biology and treatment for triple negative breast cancer
Journal of International Oncology 2016;43(7):526-528
Triple negative breast cancer (TNBC)is difficult to benefit from endocrine therapy or tras-tuzumab targeted drug therapy.Biological overexpression of breast cancer susceptibility gene 1,p53 gene,vas-cular endothelial growth factor and microRNA suggests that TNBC is easy to metastasis and recurrence and has a poor prognosis.Exploring the molecular subtypes of TNBC,setting out the treatment plan for subtypes and finding the corresponding monoclonal antibody targets are the research direction of TNBC in the future.
3.Relationship between Self-concept and Mental Health in Middle School Students
Chinese Journal of Clinical Psychology 1993;0(01):-
To explore the relationship between self-concept and mental health. Methods:398 middle school students were tested by SCL-90 and Song-Hattie Self-concept Scale. Results: The correlation coefficients between the total score of SCL-90 and academic self-concept, non-academic self concept and total self concept were -0.22, -0.21 and -0.23 respectively. Conclusion: Self concept was significantly correlated with mental health in middle school students.
4.Research progress on brachytherapy for recurrent cervical cancer
Chinese Journal of Radiation Oncology 2021;30(3):297-300
Cervical cancer is a common malignancy in women. Surgery and radiotherapy are the main therapeutic approaches. The recurrence rate of cervical cancer is high and the prognosis is relatively poor. Recurrent cervical cancer can be classified into the central pelvic, lateral pelvic and extra-pelvic recurrence. The management of recurrent cervical cancer mainly depends on previous therapeutic approaches and the recurrence site. Surgical resection is the optimal option for patients who have no history of radiotherapy, if feasible, chemoradiotherapy±brachytherapy can be considered. Patients with central pelvic recurrence after radiotherapy are suitable candidates for pelvic exenteration±intraoperative radiotherapy. However, the indications are highly selective, the incidence of postoperative complications is high and the quality of life is poor. Patients with lateral pelvic recurrence after radiotherapy could be treated by re-radiotherapy or chemotherapy. However, the incidence of serious side effects of re-radiotherapy is higher than that of the initial radiotherapy. The indications for stereotactic body radiotherapy are limited and the surgical skill of the surgeons is demanding. In recent years, radiotherapy technology has become more precise. Image-guided brachytherapy, such as high-dose-rate interstitial brachytherapy and radioactive 125I seed implantation, has achieved high efficacy and safety, which may provide new treatment options for recurrent cervical cancer. In this article, research progress on brachytherapy for recurrent cervical cancer was summarized and reviewed.
5.Exploration of Basic Organization Structure of Hospital Social Evaluation
Jing LIU ; Junjie LI ; Rong WANG
Chinese Hospital Management 2017;37(6):34-35
Interim Measures for Hospital Review points out that social evaluation is one of the important contents of hospital periodicity evaluation.Through the literature review and analysis,the definitions of hospital social evaluation are examined,and the agents,subjects and contents involved in basic organization structure of hospital social evaluation are analyzed.The theoretical findings can be used to help to eStablish hospital social evaluation system.
6.Medical Electronics Teaching Reform and Exploration
Yancheng LI ; Junjie LIU ; Juan XING
Chinese Journal of Medical Education Research 2006;0(09):-
Medical electronics has become an elective or the compulsory course in medical colleges,but the teaching condition has restricted the quality of teaching,so the educational reform is imperative.This article analyzed the medical electronics teaching actuality,and then according to their own teaching reform practice,put forward the future direction of the teaching reform on medical electronics —— strengthening teachers training and improving teaching condition.
7.Application of computer-assisted instruction for Case-based teaching in medical imaging
Jianzhong ZHU ; Jian QIN ; Junjie LIU
Chinese Journal of Medical Education Research 2003;0(02):-
Objective A study was performed to better define the teaching outcome of computers in teaching medical imaging. Methods 150 4rd-year students were randomly assigned to four groups and experimental group exposed to 20 radiology cases as well as to a voluntary weekly radiology lecture. Group A used computer-based cases with interactive elements; group B used computer-based cases without interactive elements; group C used paper-based cases with interactive elements; and group D was not exposed to the cases and served as a control group. Results On a multiple-choice question test,groups A,B,and C showed significant improvemen(t+10.6%,+15.7%,+13.5%,respectively),whereas group D did not(+2.7%). On an image interpretation test,group A and group B showed the most improvement (+15.8%,P
8.Research on Relationship between Bronchioloalveolar Carcinoma Syndromes and Metastasis by Thoracoscopic Techniques
Junjie MA ; Huiping LIU ; Yilai ZHANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(5):1128-1132
This study was aimed to reveal the relationship of bronchioloalveolar carcinoma (BAC) syndromes and metastasis, in order to provide new scientific basis for syndrome differentiation, treatment and prognostic assessment, which proved the scientificity and feasibility of internal and external inspection. A total of 60 BAC cases were divid-ed into two groups according to the syndrome of deficiency and excess. Another 30 cases of benign pulmonary nod-ules were simultaneous collected in the physical examination as control group. The quality of life (FACT-L) was scored one day before operation for patients in each group. The thoracoscopic technique was used in the biopsy of targeted tissues, in order to reveal indicators related with metastasis. The results showed that the comparison of FACT-L score of patients from two syndromes of BAC and that of the control group indicated that the score of physi-ological state, social/family condition, emotional condition, functional situation, additional situation and total score of the previous one were obviously higher than the latter one (P < 0.01). And the score of patients in the deficiency syndrome group was higher than that of the excess group with statistical significance (P< 0.01). The comparison be-tween the tumor tissues of patients from two syndromes of BAC and the benign pulmonary nodules showed that the VEGF, MMP-2, MMP-9 of the previous one were higher than the latter one (P< 0.01). The comparison between two syndromes showed that all indexes of the deficiency syndrome were higher than the excess syndrome (P < 0.01). It was concluded that syndromes of BAC was related with metastasis.
9.Clinical internship and innovation of psychiatry from the perspective of medical undergraduates
Junjie GU ; Bian LIU ; Jun ZHANG
Chinese Journal of Medical Education Research 2013;(2):169-172
Objective To evaluate the current methods for psychiatry clinical internship and needs for innovation from the perspectives of medical undergradutes.Methods Independent interview on patients and their relatives as well as social psychological interview were conducted for five-year psychiatry majors in clinical internship (n =72).Self-made questionnaire was used to investigate the teaching feedback concerning the practice effect and teaching method tendency.Data were analyzed by t test and P < 0.05 signifies statistically significant differences.Results Medical students considered the clinical internship as the main source of psychiatry knowledge (rising from 29.4 % (20/69) to 36.2% (25/69),t =4.67,P <0.01).Respective interviewing with patients and their families and then doing focus-group discussion was the most acceptable method for medical undergraduates:82.6%(57/69) of medical undergraduates thought this method helped expose defects of clinical skills and prejudice against psychiatry; 54.3% (37/69) of medical undergraduates thought this method was more beneficial to acquire psychiatry knowledge.The second acceptable method was the demonstration of a typical case by teacher:27.3% (19/69) thought this method helped expose defects of clinical skills and prejudice against psychiatry; 27.2% (19/69) thought this method was more beneficial to acquire psychiatry knowledge.62.0% (43/69) of medical undergraduates ranked the characteristics of the symptomatology and core symptoms differentiation as the first place.49.0% (34/69) considered the training of interviewing skills with patients as the second important in the clinical training.91.3% (63/69) expected to see more kinds of mental disorders.65.2 % (45/69) expected to learn more about the interviewing skills.Conclusions It is necessary to pay more attention to the method of doing respective interviewing with patients and their families and then making focus-group discussion.Meanwhile training of interviewing skills in the clinical internship of psychiatry should be enhanced.
10.Study on genetic epidemic of ankylosing spondylitis
Junjie LI ; Jiafen JI ; Changyun LIU
International Journal of Pediatrics 2013;40(4):413-415
Objective To investigate the epidemiological situation and the mode of inheritance of ankylosing spondylitis (AS).Methods The AS prevalence investigation was carried out from three different areas in Shandong Province to investigate the incidence of the 80 patients' family members of sick group and calculate the heritability of AS.Results After the investigation and calculation we found the incidence of primary relatives was 7.23%,the heritability was 85.94%,the incidence of secondary relatives was 0.94% and the heritability was 57.4%,the incidence of thirdly relatives was 0.39%,the heritability is 36.2%,the average heritability among primary,secondary and thirdly was 68.47% ± 1.64%.Separation ratio was 0.088 9.Conclusion AS is a polygenic disease,its average heritability was 68.47% ± 1.64% and separation ratio is 0.088 9.By this research,the incidence risk of AS patients' pedigree offspring can be assessed,then strengthen protective factors to reduce the incidence of the disease to provide the basis for eugenics.