Objective To analyze the occurrence of sharp injuries among health care workers(HCWs),and put forward suggestions for safety management of sharp inj uries.Methods Recorded form of sharp inj uries reported in a hospital in August 2006-July 2015 were analyzed retrospectively,relevant data were analyzed statistically.Results A total of 211 sharp injuries occurred among HCWs were reported,sharp injuries mainly occurred among nurses(n=118,55.92%)and doctors(n=83,39.34%);117(55.45%)sharp injuries occurred in HCWS whose length of service was≤5 years;the main occurrence locations of sharp injuries were surgical ward(n=67,31.75%),internal medicine ward(n=65,30.81%),and outpatient as well as emergency departments(n=33,15.64%);the main de-vices causing sharp injuries were syringe needle(n=91,43.13%),suture needle(n=34,16.11%),and scalp nee-dle/transfusion needle(n=27,12.80%);the main injury-related manipulations were all types of injection(n=40, 18.95%),intravenous transfusion (n=38,18.00%),and surgical suturing/cutting (n=36,17.06%).The main opportunities of injuries was during manipulation(treatment,examination,operation,n=109,51.66%).Among bloodborne pathogens contaminated devices,contaminated by HBV,HCV,and HIV were 95 (76.61%),25 (20.16%),and 4 cases(3.23%)respectively.There was no bloodborne pathogen infection occurred.155(73.46%) of 211 HCWs were inoculated hepatitis B vaccine.Conclusion Prevention of sharp injuries should be focused on nurses and doctors who work for≤5 years,HCWs in surgical ward,internal medicine ward,and outpatient as well as emergency departments.Prevention of sharp inj uries during manipulations such as inj ection,intravenous transfu-sion,suturing/cutting should be intensified.Related hospital departments should improve the reporting process and intensify follow-up.

Objective To observe the efficacy of Danhong injection combined with low-molecularweight heparins in treating unstable angina pectoris.Methods One hundred and three cases of unstable ansina pectoris were enrolled and divided into group A and B,Group A were given Danhong injection and lowmolecular-weight hepafins,Group B were given routine treatment.Results The overall response rate of group A was 90.7％ and it was 74.0％ for group B.The difference was significant (x2 =4.90,P＜0.05).Conclusion Treatment with Danhong combined with low-molecular-weight heparins produced a good outcome in the patients with unstable angina pectoris.

The case teaching method was applied in the course of Clinical Rehabilitation. The key factors included the case design, operation and assessment in its working program. In the teaching of Clinical Rehabilitation, the use of the case teaching method can stimulate the interest of studence and enhance the effect of teaching.

OBJECTIVE To study the dynamic changes of drug resistance and infectious distribution of Pseudomonas aeruginosa and guide drug treatment in clinic.METHODS The susceptibility to 12 antibiotics were detected in 758 P.aeruginosa strains.RESULTS The resistance of P.aeruginosa to 12 antibiotics was increased in the past four years.The resistant rate to imipenem and amikacin was below 25%.The infection caused by P.aeruginosa happened frequently in Department for Cadre,Intensive Care Units(ICU) and Department of Respiration.Among 758 strains of P.aeruginosa,87 strains were identified multi-drug resistant and found more frequently in Department for Cadre,ICU,Department of Respiration and Department of Burn.CONCLUSIONS The drug resistance of P.aeruginosa has become a more serious problem than before.The monitor of drug-resistant P.aeruginosa could guide treatment and provided epidemiologic and dynamic changes data for clinic.The infection of multi-drug resistant P.aeruginosa meets most frequently in patients who received antibiotic treatment for a long time and had a long stay in the hospital.

Adult ; Humans ; Male ; Maxillary Sinus ; Xanthogranuloma, Juvenile

Objective To analyze the common causes and clinical features associated with hoarseness in chil-dren of different ages. Methods The data of 2 500 children suffering from hoarseness were analyzed with electronic [aryngofiberscopy retrospectively. Results There were 1 746 males and 754 females. The top 5 causes of hoarseness were vocal cord nodules(44.2%, 1 105 cases), vocal hypertrophy (38.2% ,955cases), acute and subacute laryngitis (6.5 %, 163cases), the paralysis of vocal cord(6.82 %, 141cases), and laryngeal papilloma(1.6 %, 40cases). These five diseases were common in children with hoarseness with 2 404 out of 2 500. 37.12% of the children were under school ages as the largest age group and the ratio of male and female was 2.32 : 1. The top five diseases were statisti-cally distributed in different age groups (P<0.01) . Conclusion The main causes of hoarseness were different in different age groups. The preschoolers made up the largest group (928/2 500), showing the greatest incidence of hoarseness in children . The incidence for male patients was higher than female and the vocal cord nodules was the top disease (1 105/2 500 cases,44.2%). Hoarseness in children was different from that of adults so that to under-stand the characteristics of this disorder in children will be beneficial to the proper diagnosis and effective treatment.

Objective To explore prognostic relative factors of different therapy for patients with intracrani-al aneurysm. Methods In 93 intracranial aneurysm patients, 38 cases were managed through craniotomy, in whom the effects of operation time, intraoperative aneurysmal rupture(IAB), temporary arterial occlusion (TAO)on 30-day and 6-month prognosis were investigated; while other 67 cases experienced endovascular treatment,in whom the simi-lar parameters of the different therapy, types of endovascular treatment, and intracranial aneurysm embolization were evaluated. 30 days and 6 months prognosis were regarded as the dependent variable, and SPSS for Windows 11.5 was adopted for data processing. Chi-Square test was performed. Results IAR exerted significant difference to 30 days and 6 months prognosis in patients undergoing craniotomy and clipping, there were 42 intracranial aneurysm, of which 16 aneurysm ruptured (χ2 = 5. 203,10. 886, P < 0.05 ). For patients undergoing endovascular treatment, the new ma-terial application could improve 6 months prognosis, in whom there were totaly 74 intracranial aneurysm, of which 23 aneurysm were managed by the use of old material for endovascular treatment and 51 aneurysm were managed by the use of new material for endovascular treatment(χ2 = 5. 544 and RR = 2. 364,95% CI 1. 197～4.669 ,P < 0.05 ). Un-successful ratio in the endovascular treatment was reduced simultaneously,from 43.5% (old material group) to 18.0% ( now material group) (χ2 = 5. 542,P < 0.05). Conclusions IAR is the important risk factor, which effects 30 days or 6 months prognosis of patients with intracranial aneurysms managed through craniotomy and clipping. The new material application in the endovascular treatment improves 6 months prognosis, meanwhile unsuccessful ratio in the endovascular treatment is reduced simultaneously.

Objective Stress radiography provides an objective tool to measure posterior knee instability.This study was conducted to evaluate the intraobserver and interobserver reliability of measurements using Telos device to quantify posterior knee instability,compared wim KT-1000 and PDT test for consistency analysis.Methods From October 2008 to June 2009,68 stress radiographs in 34 patients with posterior knee instability were taken using Telos device.The amount of posterior displacement on the radiographs was measured independently by 2 surgeons on 2 separate occasions.Changes in intraclass correlation coefficients(ICCs)were examined to assess the intraobserver and interobserver reliability of the measurement,and were compared with those from KT-1000 and PDT test for consistency analysis.Results Intraobserver ICC was 0.992,while interobserver ICC Was 0.991.There was no significant difierence between Telos and KT-1000 in pair-t test.The data from Telos device was consistent with KT-1000.The coincident ratio Of PDT test was 20% while the posterior displacement of the tibia calculated on stress radiography was 5-10 mm.The coincident ratio of the PDT was 71.4% while the posterior displacement of the tibia calculatcd from stress radiography was 10-15 mm.Conclusion Using Telos device for stress radiograph provides a reproducible method to quantify posterior knee instability,and the consistency between Telos divece and KT-1000 was reliable.The coincident ratio of the PDT test with stress radiography increased when the posterior displacement of the tibia from stress view became more severe.

Hyperhomocysteinemia is an important independent risk factor for cardio-cerebrovas- cular diseases.Studies in recent years have suggested that hyperhomocysteinemia is also an independent risk factor for vascular dementia and Alzheimer's disease.Mild vascular cognitive impairment is the prophase of vascular dementia.Mainly through the damage of vascular wall structure and its function,homocysteine may has correlation with mild vascular cognitive impairment.

Background Myopia is an important risk factor of glaucoma.Investigation of the characteristics of retinal nerve fiber layer thickness (RNFLT) and optical head morphology in myopia patients was helpful for differentiating myopic change and glaucomatous change in myopic eye.Objective This study was to investigate the peripapillary RNFLT and papillary parameters in different degrees of myopic eyes.Methods A 5-year case series study was retrospectively analyzed.Total 168 eyes of 168 myopic patients without visual field defect were recruited and divided into three age matched groups according to spherical equivalent (SE):low myopia group (SE:-0.25 ～-0.75 D) (57 eyes),moderate myopia group (SE:-3.0 ～-5.75 D) (57 eyes) and high myopia group (SE:-6.0～-12.0 D) (54 eyes).The RNFLT was measured with scanning laser polarmetry (GDxVCC) and papillary parameters measured with confocal scanning laser ophthalmoscope (HRT Ⅱ).Intergroup difference of parameters from GDxVCC and HRT Ⅱ were analyzed using one-way analysis of variance and SNK-q test.The correlations between spherical equivalent and RNFLT or papillary parameters was evaluated with multiple linear regression analysis.Results The global average,superior and inferior average,standard deviation,inter-eye symmetry of RNFLT were gradually reduced as the increase of SE with significant differences among the three groups (F=6.193,7.127,3.874,4.098,3.128,P ＜ 0.05).Global average,superior average,standard deviation,inter-eye symmetry of RNFLT were significantly lower in the high myopia group than those in the low myopia group (q =5.334,4.526,4.586,20.679,P＜0.05).An statistically significant reduce in inter-eye symmetry was seen between the high myopia group and the moderate myopia group (q =6.225,P＜0.05) as well as between the moderate myopia group and the low myopia group (q =10.035,P＜0.05).The multiple regression analysis showed that global average,superior average,inferior average,standard deviation,inter-eye symmetry of the R NFLT decreased with the increase of SE (β=0.441,t=6.329,P=0.000;β=0.471,t=6.880,P=0.000;β=0.339,t=4.641,P=0.000;β=0.389,t=5.445,P =0.000 ; β =0.338,t =4.621,P =0.000).Cup volume,linear cup/disk ratio,mean cup depth and maximum cup depth in the high myopia group were significantly lower than those of the moderate myopia groups (q =2.603,P =0.0l 1 ;q =2.105,P =0.037 ; q =2.825,P =0.006 ; q =2.495,P =0.014).Mean cup depth and height variation contour were significantly decreased in the high myopia group compared with the low myopia group (q =2.562,P =0.013 ;q =2.203,P =0.030).Rim area,rim volume,height variation contour were positively correlated with the degree of myopia (β=0.195,t=-2.565,P=0.011 ;β=0.199,t=-2.611,P=0.010;β=0.177,t =-2.311,P=0.022) ; while mean cup depth were negatively correlated with the degree of myopia (β =0.153,t =1.997,P =0.047).Conclusions As the increase of myopia degree,superior and inferior quadrants of RNFLT and cup depth are declined,but rim volume is elevated.Myopia is a confounding factor when RNFL data is interpreted by GDxVCC and papillary parameter by HRT Ⅱ.