This paper systematically introduces the progress and main practices of the three-year campaign for prevention and treatment of endemic diseases, discusses the effectiveness of prevention and treatment of endemic diseases in improving the health level of people in endemic areas and getting rid of poverty, heading for a well-off life in an all-round way, and demonstrates the experience of prevention and treatment of endemic diseases in China and its far-reaching influence on the process of consolidating the achievements of poverty alleviation and realizing the strategy of rural revitalization.

Objective To observe expression and significance of inflammatory factor during perioperative and follow-up periods after endovascular stents in patients with cerebral arterial stenosis.Methods 54 patients diagnosed as cerebral arterial stenosis by digital substraction angiography (DSA) were selected as the stent group and treated with endovascular stents; another 32 subjects had the same disease but not accepted stenting were considered as the control group. Interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) contents were measured at different time points during perioperative and follow-up periods in the two groups. Stage A represented as day one before angiography or catheterization; stage B as 6 hours postoperatively (stent group) or 6 hours after diagnostic angiography (control group); stages C～I as 12, 24, 48, 72 hours, 1 and 6 months after stent insertion (stent group) or the same time points after angiography (control group).Results Contents of IL-6 and hs-CRP of the stent group were similar as the control group in the stage A ( P>0.05), but significantly higher than that of the control group during stages B～I ( P<0.01～0.05). Among 54 patients of the stent group, 21 cases had restenosis 6 months postoperatively (38.89%). Contents of IL-6 and hs-CRP of the patients were similar as those without restenosis in stages A～F postoperatively ( P>0.05), but significantly higher than that of the cases without restenosis in stages G and I postoperatively ( P<0.01～0.05).Conclusion Endovascular stents can increase the contents of IL-6 and hs-CRP of patients with cerebral arterial stenosis; in addition, high expression of them is the risk factor of post-stent restenosis during follow-up period.

Low molecular weight heparin(LMWH)is a kind of anticoagulant used in both the prevention of clot formation in the blood vessels(thrombosis)and the treatment of conditions caused by clot formation or embolization.They are agents formulated from chemical or enzymatic depolymerization of unfractionated heparin.In the past decade,LMWH has been extensively evaluated in many clinical settings.The applications of LMWH in recent years are reviewed.

Objective:To explore the effects of radiation on hippocampus neuron and the related damage mechanism in order to provide the theory base for treatment strategy of radiation brain injury. Methods:We looked up the scientific literature including following methods. Pregnant mice were irradiated with tritiated water, and then the contents of SOM in pars intermedia and AVP in hypothalamus of newborn mice were detected by radioimmunoassay. Pregnant rats were irradiated with tritiated water or X-ray, and the neuronal cells derived from the newborn rats were cultured. The morphology of cultured neuronal cells was compared with those of normal neuronal cells. The number of apoptotic cells in cortical fifth layer was measured by HE staining. Results:After radiation with tritiated water, the level of SOM in pars intermedia of newborn mouse and AVP content in hypothalamus content of male newborn mouse significantly increased and decreased, respectively. Radiation with tritiated water could result in the morphology change of neuronal cells and increase the percent of apoptosis cells in cortical fifth layer. Moreover, the percent of apoptosis cells in tritiated water group was higher than that in the X ray group. Conclusion: Radiation could impact on brain neuropeptide contents, and neurobehavioral, learning and memonic ability, result in the morphology change of hippocampal neurons, and induce the midbrain cells apoptosis.

To investigate the correlation between traditional Chinese medicine (TCM) syndrome and short-term prognosis of ischemic stroke.

Objective To explore the experience of surgical treatment for appendiceal carcinoid.MethodsThe clinical data of 12 appendiceal carcinoid cases received surgery were retrospectively studied.ResultsPreoperatively,all the 12 cases were considered as appendicitis.The definite diagnosis was verified by pathologic study postoperatively.Among the 12 cases, tumors less than 1 cm 9 cases, between 1 cm to 2cm 2cases, but without serosal involvment or lymph node metastasis(2 cases) recieved simple appendectomy.One case with a tumor larger than 2cm and serosal involvment underwent fight hemicolectomy.ConclusionOwing to its lack of specific symptoms,the diagnosis of appendiceal carcinoid was usually reached after operation.The choice of surgical procedures should based on the size and depth of invasion of the tumor and lymph node metastasis status.

Colorectal neuroendocrine neoplasm (NEN) is originated from colorectal neuroendocrine cells.The incidence of colorectal NEN is low,however it has been increasing in recent years.As the research work has gone further,WHO has graded colorectal NEN to neuroendocrine tumor,neuroendocrine carcinoma,mixed gland-neuroendocrine carcinoma and hyperplastic and pre-neoplastic lesions.Although colorectal NEN cells can produce hormones and have endocrine functions,the clinical symptoms may not be shown.The diagnosis and treatment for colorectal NEN are different according to different classifications and stages.

Objective To evaluate the efficacy of surgical repair for non-circumferential defect of bile duct in Mirizzi syndrome.Methods The clinical data of 42 patients with Mirizzi syndrome with non-circumferential defect of bile duct who were repaired using own tissues such as gallbladder pedicle flap,umbilical venous flap and omental flap were analyzed.The defect in the bile duct were repaired using gallbladder pedicle flap in 30 patients,umbilical venous flap in 8 patients and omental flap in 4 patients.Results All patients were operated successfully.There was no operative mortality.There were 2 patients who developed postoperative complications.There was one postoperative bile leakage in a patient who was repaired using an umbilical venous flap.The other complication was residual bile duct stones.The patient with postoperative bile leakage was drained through a drainage tube which was removed after 7 d.The residual bile duct stones were removed by endoscopy through a T-tube sinus after 9 months.All patients were confirmed by T-tube cholangiography after 9-12 months to have no stones,bile duct stenosis or any other abnormalities.The T-tube was then removed.All patients were followed up for 1-5 years,and had no cholangitis,abdominal pain,jaundice or fever.Conclusions Using own tissues such as gallbladder pedicle flap,umbilical venous flap and omental flap to surgical repair the defect in the bile duct of patients with Mirizzi syndrome is effective.This surgical treatment is a good choice.

To understand the current situation of public health service system by using diect network report,system report and questionaire surey, so as to provide reasomable suggestion for the existing problems.

Emodin is the main effective monomer of Rhubarb, which has a variety of pharmacological actions and valuable clinical applications.Recently, there are many reports about molecular mechanisms of emodin pharmacological actions,and they givehighly attention on the dephlogisticating and antineoplastic effects. These effects are achieved through affecting the concentration and transportation of ions, resisting of oxidation and free radical, and affecting the secretion of inflammatory factor and the enzyme activity and apoptosis and so on. This article summarizes the reports and hopes to provide theoretical basis for the practical application.