1.Application of the video of head-eye movement training in vestibular rehabilitation
Chunting CAO ; Qi LI ; Yuanyuan LIU ; Ying TIAN ; Yuan WANG ; Ke QI ; Litang CAO
Chinese Archives of Otolaryngology-Head and Neck Surgery 2017;24(5):245-247
OBJECTIVE To study the effect of the video of head-eye movement training in vestibular rehabilitation.METHODS 37 patients aged between 30 and 76 years old with vestibular dysfunction underwent two weeks of rehabilitation with the video of head-eye movement training. The results of dizziness handicap inventory (DHI), dizziness analogue scale, and the Romberg static balance tests were recorded before and after the rehabilitation.RESULTS After the rehabilitation, there was significant decrease in the scores of DHI and dizziness analog scale(allP>0.001), and there was significant improvement in the time of Romberg static balance tests(P>0.001).CONCLUSION The video of head-eye movement training is an effective method in vestibular rehabilitation.
2.Expression of FHIT gene protein in laryngeal carcinoma.
Litang CAO ; Xiaoming CHEN ; Binquan WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2008;22(3):122-123
OBJECTIVE:
To investigate the role and clinical significance of the expression of FHIT gene in development and progression of laryngeal squamous cell carcinoma(LSCC).
METHOD:
The expression FHIT protein was detected by immunohistochemistry method in the 52 cases with LSCC and 23 cases of adjacent cancer tissues and 10 cases of laryngeal normal mucosa. The expression of FHIT was analyzed in LSCC with different clinicopathological parameters.
RESULT:
The expression of FHIT in normal tissues (90.0%) and adjacent tissues (78.3%) was obvious higher than that in LSCC (46.2%), which had statistical significant difference (P < 0.01). There was a positive correlation between FHIT expression and TNM staging, lymph node metastasis; but not pathological grade.
CONCLUSION
The loss of FHIT expression may be correlated with the development and progression of laryngeal carcinoma. FHIT may be an important tumor suppressor gene in LSCC.
Acid Anhydride Hydrolases
;
metabolism
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Adult
;
Aged
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Carcinoma, Squamous Cell
;
metabolism
;
pathology
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Female
;
Humans
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Laryngeal Neoplasms
;
metabolism
;
pathology
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Male
;
Middle Aged
;
Neoplasm Proteins
;
metabolism