1.The value of PCT, CRP, TNF-α and free DNA in predicting the development of MODS in patients with multiple trauma
Rui FU ; Heping XIANG ; Liqi YANG ; He LI ; Ming GAO ; Wei WANG ; Datong JIANG
Chinese Journal of Emergency Medicine 2013;22(8):850-854
Objective To explore the value of peripheral blood serum levels of PCT,CRP,TNF-α and free DNA of cells in predicting the development of MODS in patients with multiple trauma.Methods Complete detail clinical data of 54 casualties with multiple trauma admitted within 24 hours after accident from January 2011 through January 2012 were collected for retrospective study.The patients were divided into MODS group and non-MODS group according the criteria set forth by the Chinese Society of Critical Care and Emergency Medicine in 1995 national conference.The data of two groups are comparable,and data of another 20 healthy subjects undertaking routine annual physical examination were taken as control.The peripheral blood levels of PCT,CRP,TNF-α and free DNA of patients of two groups were determined 1 d,2 d,3 d,and 5 days after admission.Then the results were analyzed and compared between groups.Results Compared with non MODS group,the levels of PCT,CRP,free DNA of cells in MODS group were significantly higher (P < 0.05),but there was no deference in TNF-α between MODS group and non-MODS group (P > 0.05).When the relative risks of increased PCT (PCT≥6 mg/L),increased CRP (CRP≥ 130 mg/L)、and increased free DNA of cells (free DNA ≥ 10 0005/L) were analyzed,the presence of these 3 biomarkers with high levels occurred at the same time was the most accurate way to predicts MODS in 6.00 relative risk (RR),and the positive predictive value was 100%.Conclusions PCT,CRP,free DNA of cells could be the predictors of MODS in patients with severe multiple trauma,and the presence of high levels of these three biomarkers appearing together had high sensitivity and specificity for prediction.
2.Correlation analysis of health belief and stroke patients′ family function
Gang CHEN ; Yanfei CAO ; Yuchun WANG ; Bo LIU ; Kai WANG ; Xiaomin WANG ; Liqi FU
Chinese Journal of Modern Nursing 2015;(15):1760-1762
Objective To analyze the correlation family function and health beliefs of stroke patients. Methods The questionnaire survey was carried out in 95 stroke patients with family assessment device ( FAD) and health belief scale. The relationship between cerebral stroke patients family function and health beliefs was analyzed with correlation analysis method. Results The total family function score of stroke patients was (133.57 ±14.78), average clause score (2. 20 ± 0. 31). The score of clauses from high to low were the emotional reaction, behavior control, communication, emotional involvement, problem solving, role function, general function. The patients′total health belief score was (109. 27 ± 11. 94), average clauses score (3. 20 ± 0. 35). Each clauses score from high to low was health motivation, self-efficacy, benefits, susceptibility, severity, obstacle. Family function score of each dimension had negative correlation with health belief scores (P<0. 05). Conclusions Stroke patients health belief level needs to be improved, and family function has a promoting effect on health belief. Doctors and nurses should enhance health education. The family function is conducive to the promotion of health belief for patients.