No abstract available.
Liposarcoma, Myxoid*

Myxoid liposarcoma is a subtype of liposarcoma. This specific subtype can be identified based on its characteristic histological and cytogenetical features. The tumor has a fusion transcript of the CHOP and TLS genes, which is caused by t(12;16)(q13;p11). Most of the fusion transcripts that have been identified fall into three categories, specifically type I (exons 7-2), type II (exons 5-2), and type III (exons 8-2). A total of seven myxoid liposarcomas associated with the rare phenomenon of cartilaginous differentiation have been documented in the literature. Currently, only one of these cases has been cytogenetically analyzed, and the analysis indicated that it was a type II TLS-CHOP fusion transcript in both the typical myxoid liposarcoma and cartilaginous areas. This study presents a second report of myxoid liposarcoma with cartilaginous differentiation, and includes a cytogenetical analysis of both the myxoid and cartilaginous areas.
Cartilage ; Liposarcoma ; Liposarcoma, Myxoid

Liposarcoma of paratesticular origin is extremely rare and preoperative diagnosis is unusual. Myxoid type or liposarcoma is in general less malignant than testicular tumor and orchiectomy with high ligation and wide excision of tumor mass are probably the treatment of choice. We are present a case of myxoid liposarcoma and reviewed literatures.
Diagnosis ; Ligation ; Liposarcoma ; Liposarcoma, Myxoid* ; Orchiectomy

Liposarcoma of paratesticular origin is extremely rare and preoperative diagnosis is unusual. Myxoid type or liposarcoma is in general less malignant than testicular tumor and orchiectomy with high ligation and wide excision of tumor mass are probably the treatment of choice. We are present a case of myxoid liposarcoma and reviewed literatures.
Diagnosis ; Ligation ; Liposarcoma ; Liposarcoma, Myxoid* ; Orchiectomy

Liposarcomas are one of the most common soft-tissue sarcomas in adults. They usually arise in the deep soft tissues, and patients present with large painless masses. Four major types of liposarcomas are generally recognized and have epidemiologic and prognostic differences: atypical lipomatous neoplasm/well-differentiated; myxoid/round- cell; dedifferentiated; pleomorphic variants. Myxoid liposarcoma is the second most common type of liposarcoma, representing 30~40% of all liposarcomas in the extremities. We report a case of myxoid liposarcoma in a 78-year-old man who presented with an asymptomatic, firm, deep-seated mass in the lateral aspect of his left upper arm.
Adult ; Aged ; Arm ; Extremities ; Humans ; Liposarcoma ; Liposarcoma, Myxoid ; Sarcoma

Liposarcoma of spermatic cord is a rare malignant tumor. Because preoperative clinical diagnosis is very difficult, final diagnosis is made by postoperative pathologic examination. This tumor grows slowly and tends to recur locally. Therefore radical inguinal orchiectomy with wide local excision appears to be adequate treatment. We report a case of myxoid liposarcoma of right spermatic cord in 35 year-old male with a brief review of the literatures.
Adult ; Diagnosis ; Humans ; Liposarcoma ; Liposarcoma, Myxoid* ; Male ; Orchiectomy ; Spermatic Cord*

The application of fine needle aspiration (FNA) cytology to the soft tissue tumors had been neglected. In recent years, however, FNA has been used increasingly in the preoperative diagnosis of these tumors due to its usefulness and accuracy. We present 3 cases of liposarcoma, myxoid, myxoid with round cell, and pleomorphic, diagnosed by FNA cytology with histologic confirmation. Good correlation between histologic and FNA cytologic findings was found. Although the cytologic appearances of liposarcomas varied with histologic type, the main criterion was the presence of atypical multivacuolated lipoblast with characteristically scalloped nuclei.
Biopsy, Fine-Needle* ; Diagnosis ; Liposarcoma* ; Liposarcoma, Myxoid ; Pectinidae

Humans ; Liposarcoma/genetics* ; Liposarcoma, Myxoid/genetics* ; Transcription Factor CHOP/genetics*

Adult ; Humans ; Liposarcoma, Myxoid ; diagnosis ; Male ; Mediastinum ; pathology

The cytologic findings in fine needle aspiration of a case of myxoid liposarcoma of the mediastinum are described. The smear and cell block of the aspirate revealed solid clusters with background of amorphous material and scattered single tumor cells. The clusters were moderately cellular and consisted of atypical lipoblasts in varying stages of differentiation and delicate plexiform capillaries. Good correlation was found between the histologic and cytologic findings in the fine needle aspirates. The differential diagnosis between myxoid liposarcoma and other myxoid soft tissue tumors is discussed.
Biopsy, Fine-Needle* ; Capillaries ; Diagnosis, Differential ; Liposarcoma, Myxoid* ; Mediastinum* ; Needles