No abstract available.
Lipodystrophy*

No abstract available.
Adipose Tissue* ; Apoptosis ; Lipodystrophy*

No abstract available.
Lipodystrophy, Congenital Generalized*

Humans ; Lipodystrophy ; congenital

Lipodystrophy is a disorder characterized by the loss of subcutaneous adipose tissue which is inherited or heterogeneously acquired. We report 3 uncommon cases of localized lipodystrophy on face which distinguished 1 year after cyst enucleation of mandibular posterior area.]]>
Atrophy ; Lipodystrophy ; Subcutaneous Fat

A boy, aged 66 days, was admitted to the hospital due to subcutaneous nodules for 46 days and abdominal distension for 10 days. The main clinical manifestations were loss of adipose tissue, subcutaneous nodules, insulin-resistant diabetes, hypertriglyceridemia, and hepatic steatosis. The boy was diagnosed with congenital generalized lipodystrophy type 1 (CGL1). His condition was improved after administration of middle-chain fatty acid formula milk and insulin injection or oral metformin. Gene testing revealed a homozygous mutation, c.646A>T, in the AGPAT2 gene, and both his parents were carriers of this mutation. This case of CGL1 has the youngest age of onset ever reported in China and multiple subcutaneous nodules as the initial symptom.
Adipose Tissue ; China ; Fatty Liver ; Humans ; Infant ; Insulin Resistance ; Lipodystrophy ; Lipodystrophy, Congenital Generalized ; Male

Partial lipodystrophy(PLD) is a rare disorder characterized by frequent occurrence in women, usually onset in childhood, and slowly progressive symmetrical loss of subcutaneous fat on the upper half of the body. The etiology is unknown. However, many immunologic abnormalities were reported in PLD. Herein, we report a case of PLD in a 34-year-old man with familial occurrence of PLD in his brother.
Adult ; Female ; Humans ; Lipodystrophy, Familial Partial* ; Siblings ; Subcutaneous Fat

Membranous lipodystrophy is characterized by the presence of microcysts lined by amorphous, eosinophilic material with an arabesque appearance. We experienced a case of a 72-year-old man who had dark brownish, pruritic papules on the arms, legs, and back. Histopathologic examination of a biopsied lesion showed homogeneous, eosinophilic material in the papillary dermis, as well as membranous lipodystrophy. We report a case of membranous lipodystrophy observed in lichen amyloidosis.
Aged ; Amyloidosis ; Arm ; Dermis ; Eosinophils ; Humans ; Leg ; Lichens ; Lipodystrophy

We report a case of lipodystrophia centrifugalis abdomina]is infantilis in a 2 year 5 month male. At age 7 months, his parents noticed a bluish macule in the right inguinal region, which gradually became depressed and increased in size over a year to involve the abdomen and flank bilaterally. Regional lymph nodes were enlarged. Biopsy showed absence of subcutaneous fat in the affected area.
Abdomen ; Biopsy ; Humans ; Lipodystrophy* ; Lymph Nodes ; Male ; Parents ; Subcutaneous Fat

A case of progressive lipodystrophy affecting 19-year-old female, is reported. Two years ago, she accidentally discovered brownish pigmented, and depressed lesion on the periumbilical area. For one year after that, lipodystrophic process spread to the left lateral abdomen and chest wall in linear fashion and ceased spontaneously. Physically, she had no abnormalities on general conitions and fat distribution on whole body was also normal except the above mentioned area. Laboratory findings are with normal limits except incread ESR. Histopathologic findings showed abscence of subcutaneous adipose tissue.
Abdomen ; Female ; Humans ; Lipodystrophy* ; Subcutaneous Fat ; Thoracic Wall ; Young Adult