We report a case of histopathologically confirmed benign lipoblastoma in the retroperitoneum. The tumor presented itself as an ill-defined low density mass on a simple radiograph, as a highly heterogeneous echogenicmass on US, and fatty density mass separated by unenhanced linear septa of soft tissue density on CT. The well circumscribed and encapsulated tumor was totally removed by operation. CT is considered the modality of choice for characterizing lipoblastoma and demonstrating its location and boundary. When there is fatty density mass in there troperitoneum of a children, the possibility of lipoblastoma should be considered first.
Child ; Humans ; Lipoblastoma*

Lipoblastoma is a rare benign tumor that usually originates in children from the embryonic lipid cells of the extremities. This condition shows an early childhood occurrence, a benign nature without metastasis, a cellular composition of mainly mature lipid cells and an ability to differentiate into a simple lipoma. We have experienced a 15 month old girl who had developed a lipoblastoma in the right anterior mediastinum. Surgical resection was carried out without complications. Her postoperative course was uneventful. She has been well 6 months after the operation.
Child ; Extremities ; Humans ; Lipoblastoma ; Lipoma ; Mediastinal Neoplasms ; Mediastinum ; Neoplasm Metastasis

Lipoblastoma is a rare benign mesenchymal tumor that exhibits a tendency to invade locally but not to metastasize, and develops from embryonic remnants of white fat tissue. We experienced a case of lipoblastoma occurring in a 7-month-old girl. A small nodule developed on her right inguinal region at the age of 4 months. It had grown to be a 1.2x2.0cm in size, well-defined, volcano-like, ovoid erythematous nodule. Histopathologically it was composed of well-defined lobulated fat tissue with multivacuolated lipoblasts, undifferentiated mesenchymal cells such as stellate or spindle cells and minimal myxoid stroma. Electron microscopic findings demonstrated lipoblasts with eccentric nuclei and coarse chromatins. Complete local excision was done.
Adipose Tissue, White ; Chromatin ; Female ; Humans ; Infant ; Lipoblastoma*

Lipoblastoma is a rare, benign tumor arising from embryonic fat tissues that continue to proliferate in the postnatal period. So, lipoblastoma occurs almost exclusively in infants and children younger than 3 years of age. Published reports showed that 70~90% of cases occur before the age of 3. Histopathologically, lipoblastoma, mimicking liposarcoma, was composed of well-defined lobulated fat tissue with multilobulated lipoblasts, undifferentiated mesenchymal cells, such as stellate or spindle cells and minimal myxoid stromas. The diagnosis of lipoblastoma is important because its management differs from that of lipoma and liposarcoma. To our knowledge, there are only a few reports of lipoblastoma in the Korean dermatologic literature. Herein, we present an interesting and atypical case of lipoblastoma in 68-year-old woman.
Aged ; Child ; Female ; Humans ; Infant ; Lipoblastoma ; Lipoma ; Liposarcoma

Lipoblastoma are rare benign tumors arising from the fetal-embryonal fat that occur almost exclusively in children. About 70% of them arise in the limbs but several other sites have been reported. We have treated a 3-year-old boy who had a benign lipoblastoma in left posterior mediastinum and left supraclavicular area. CT scanning demonstrated a mass of principally fat attenuation which had a compressive effect on normal intrathoracic structures. The tumor was resected completely without complication from the left posterior mediastinum and left supraclavicular area. The tumor mass was yellowish in color and it was histopathologically confirmed to be a lipoblastoma.
Child ; Child, Preschool ; Extremities ; Humans ; Lipoblastoma* ; Male ; Mediastinum* ; Neck* ; Tomography, X-Ray Computed

PURPOSE: The purpose of this study to access MR findings of the lipomatous soft tissue tumor based on histopathologic correlation and its predictability of the histopathologic diagnosis. MATERIALS AND METHODS: We retrospectively analyzed the MR findings and photomicrographs of 9 patients with histopathologically proven lipomatous soft tissue tumors as follows;classic lipoma(4), fibrolipoma(1), lipoblastoma(2), atypical l ipoma(1) and well-differentiated liposarcoma(1). RESULTS: All cases of lipoma showed the same signal intensities as subcutaneous fat which is composed of mature fat cells. Linear low signal intensity lesions corresponded to fibrous connective tissues within lipomas. Two cases of lipoblastoma showed heterogeneous signal intensity with areas of high signal intensity brighter than subcutaneous fat on T2WI, corresponding to myxoid matrix of cytoplasm of immature lipoblasts, and the areas of myxoid degeneration within tumors. Both atypical lipoma and liposarcoma showed heterogeneous signal intensity with ill-defined margins due to presence of lipoblasts and infiltration to adjacent muscle bundles. CONCLUSION: MR image findings were well correlated with histopathologic findings of lipomatous soft tissue tumor, especially with maturity of fat cells and the signal intensity of mesenchymal components within the tumors. MR may predict the pathologic diagnosis of lipoblastoma by presence of myxoid degeneration within Ihe tumor, but atypical lipoma and liposarcoma revealed similar MR findings.
Adipocytes ; Connective Tissue ; Cytoplasm ; Diagnosis ; Humans ; Lipoblastoma ; Lipoma ; Liposarcoma ; Magnetic Resonance Imaging* ; Retrospective Studies ; Subcutaneous Fat

Lipoblastoma is a benign tumor which frequently arises in the limbs but rarely in the mediastinum, and is common in children under the age of three years. We report a case of mediastinal lipoblastoma in a 27-month-old female child complaining of dyspnea. Plain radiography demonstrated a huge well-defined mass in the me-diastinum, while CT scanning revealed a soft tissue mass with an internal hypodense portion. When radi-ographic images in children under the age of three reveal a soft tissue mass with a fat component in the mediastinum, especially where there is no calcification or a cystic component, lipoblastoma should be included in the differential diagnosis.
Child* ; Child, Preschool ; Diagnosis, Differential ; Dyspnea ; Extremities ; Female ; Humans ; Lipoblastoma* ; Mediastinum ; Radiography ; Tomography, X-Ray Computed

Mediastinal lipoblastoma is a rare benign tumor originating from embryonic lipid cells and it almost always occurs during infanthood or early childhood. It is a tumor with a good prognosis despite its potential for local invasion and rapid growth. We report here on a three years old girl who was treated for a benign lipoblastoma in the anterior mediastinum. CT scanning showed a fat containing mass without internal calcification or fluid component, and the mass showed a compressive effect on the adjacent structures. The mass was located between the pericardium and right mediastinal pleura and it was removed completely without complication. Pathologic examination revealed a benign lipoblastoma. The patient showed no evidence of recurrence at the time of the report.
Female ; Humans ; Lipoblastoma* ; Mediastinum ; Pericardium ; Pleura ; Prognosis ; Recurrence ; Tomography, X-Ray Computed

Lipoblastoma is a rare benign mesenchymal tumor that occurs primarily in infancy and childhood. There are two types of lipoblastoma: focal or diffuse (lipoblastomatosis). This is typically located in the extremities, and less frequently in the trunk, head and neck, and the retroperitoneum. Lipoblastoma is a tumor with a good prognosis with no reported metastasis, despite of its potential for local invasion, local recurrence and rapid growth. Complete surgical resection is essential for treatment, and long term follow up is needed.
Extremities ; Follow-Up Studies ; Head ; Humans ; Lipoblastoma* ; Male* ; Neck ; Neoplasm Metastasis ; Prognosis ; Recurrence ; Thoracic Wall* ; Thorax*

Lipoblastoma is a rare benign neoplasm occurring exclusively in children below the age of three years. It affects chiefly the upper and lower extremities, and less commonly head and neck area, trunk, mediastinum, mesentery, and retroperito neum. We present two cases of lipoblastoma occurring in the mediastinum of a 21-month-old boy and in the back of a 15-month-old boy. The characteristic features of Fine needle aspiration cytology smears were the presence of immature fat cells in the form of spindle-shaped cells, stellate cells and vacuolated lipoblasts along with lipocytes against a myxomatous background. Two tumors were histologically confirmed to be lipoblastomas. Lipoblastoma can be cytologically diagnosed by considering the cytologic findings and the age of the patient.
Adipocytes ; Biopsy, Fine-Needle* ; Child ; Head ; Humans ; Infant ; Lipoblastoma* ; Lower Extremity ; Male ; Mediastinum ; Mesentery ; Neck