The feasibility of medical college and university libraries to serve grass-root physicians was analyzed and the new approaches for medical college and university libraries to provide characteristic information service for grass-root physicians were studied according to the investigation of the utilization of information resources, types of information needs, satisfaction degree of information service, access methods of information, and hopes for access to medical information in grass-root physicians.

Objective To explore the diagnostic value of multi-slice spiral CT MIP-MPR image in regional lymph node metastasis of colonic carcinoma.Methods CT findings of 33 cases with pathological confirmed colonic carcinoma were analyzed retrospectively . All patients were underwent three-phase 256-slice CT dynamic enhancement scanning.All data were processed in workstation,to obtain routine MPR and MIP-MPR image.The regional lymph nodes of colon cancer were counted,and divided into 3 groups accord-ing to the short diameter of lymph node:group I (3.0-5.0 mm),group Ⅱ(5.1-10 mm),and group Ⅲ(10.1 mm up).The diag-nostic sensitivity of CT MPR and MIP-MPR image in checking out lymph nodes of different groups was compared by paired test.Re-sults The average value(x ±s )of lymph node number of three groups with routine MPR and MIP-MPR image were:group I, 3.66±1.99,6.09±2.44 (t=1 1.6,P <0.05);group Ⅱ,3.72±1.79,4.03±1.89 (t=3.73,P <0.05);group Ⅲ,1.21±1.31, 1.27±1.46(t=1.44,P >0.05).There were statistical differences in group I and group Ⅱ.Sensitivity of MIP-MPR image in chec-king out regional small and middle lymph nodes of colonic carcinoma was higher than routine MPR image.Conclusion Multi-slice spiral CT MIP-MPR image is a good way to checking out regional small and middle lymph nodes of colonic carcinoma.

Objective To investigate effects of octreotide combined with aspirin on the growth and metastasis of gastric cancer in vivo. Methods SGC-7901, human gastric cancer cell line, was implanted orthotopically in the stomach of nude mice. Octreotide or aspirin alone and the combination of the two drugs were administrated for 8 weeks to investigate the effects of them on tumor growth and metastasis. Results At necropsy, xenografts in situ were found in all stomachs of nude mice except two nude mice in the combined group. The mean volume and weight of tumors in nude mice treated with octreotide or aspirin were significantly lower than those of control group. The inhibitory rate for tumors was 60.6% in octreotide group, 39.3% in aspirin group and 85.6% in the combined group with octreotide and aspirin respectively. The metastatic rates of gastric adenocarcinoma were markedly lower in any of treatment group than that in control group. No severe side action was observed in all of treatment group. Conclusion Octreotide combined with aspirin greatly enhanced the anti-growth effect on gastric cancer in vivo when compared to using either of them and inhibited the metastasis of gastric adenocarcinoma in nude mice.

Objective To study MSCT findings and clinic value of hepatic abscesses on enhanced double-phase and(or)three-phase(arterial and protal venous phase and delayed phase),especially during arterial phase. Methods The MSCT imaging features of 20 cases with hepatic abscesses proved by operation or biopsy were evaluated on enhanced double-phase and(or) three-phase scan during arterial and portal venous phase and delayed phase ,especially during arterial phase.Results (1)The imaging features of aeterial phase were that the hepatic tissues around the lesions showed strong enhancement,but the lesions showed slight enhancement or not or peripheral enhancement. (2)The imaging features of protal venous phase were:a.circular target sign; b.circular sign; c.flower valve sign; d.multiloculated sign. (3)The imaging features of delayed phase were that the masses changed smaller or not and the belt disappeared or got vague. Conclusion The double-phase or three phase MSCT scan fully reflects the pathologic changes of hepatic abcesses and is very important to early diagnosis and differential diagnosis.

Objective To investigate the visual acuity improvement and related factors for myopia after femtosecond flap excimer laser surgery. Methods 72 myopic patients (129 eyes) in our hospital between January 2010 and December 2013 were chosen. The patients all received femtosecond flap excimer laser surgery. The visual acuity improvement after surgery was observed, and the influencing factors were analyzed. Results The distance vision (VA), near vision (NVA) and best corrected visual acuity (BCVA) significantly increased before surgery (P<0.05). Logistic regression analysis showed that preoperative BCVA, NVA, axial length, cutting ratio, axial length and time of near vision were the affecting factors of visual acuity (P<0.05). Conclusion Femtosecond flap excimer laser surgery for myopia has significant effect , but the preoperative visual acuity was affected by BCVA , NVA, cutting ratio, axial length and time of near vision.

Objective To present 8 cases of retroperitoneal laparoscopic pyelolithotomy or ureterolithotomy for the treatment of pelvis and ureteral stone. Methods 8 cases of pelvis or ureteral stone have been treated by retroperitoneal laparoscopic pyelolithotomy or ureterolithotomy. The size of the calculi was 0.8～2.4 cm with the incarceration time of 3 months～2 years.Details of the procedure were presented. Results Success has been achieved in all the patients and no complication has been observed during the 3～6 months of follow up. Conclusions Retroperitoneal laparoscopic pyelolithotomy or ureterolithotomy for the treatment of pelvis or ureteral stone is simple ,safe,less traumatic and effective.

OBJECTIVE To investigate the effect of the Qingfei decoction in the acute upper respiratory tract infections.METHODS From Jan 2004 to Sep 2006,there were 68 cases with acute upper respiratory tract infections treated with chinese medicines.The patients were divided into 2 groups:36 cases were treated with Qingfei decoction,32 cases were treated with Shuanghuanglian granules as a control.Both of the groups were treated for 5 days,the clinical symptoms such as: fever,cough and sore throat were used to evaluate the efficacy of both groups.RESULTS Both of the groups were effective;the effective rate was 88.9% and 75.0% in the Qingfei group and in the control group,respectively.There was significant difference between 2 groups(P

Objective To investigate the diagnosis of intracranial artery fenestration and its other vascular anomalies with CT angiography ( CTA ) . Methods The image data of 653 patients examined with head CTA and 39 patients diagnosed as intracranial artery fenestration in Zhongshan Hospital Affiliated to Sun Yat-sen University from January 2013 to January 2014 were analyzed retrospectively. The incidence, location,morphology of intracranial artery fenestration, and other vascular anomalies were analyzed. Results (1) In 653 patients,39 (5. 97%) with 41 artery fenestrations were detected. The detection rates of basilar artery fenestration was 3. 37% (n=22),vertebral artery fenestration was 0. 31% (n=2),anterior cerebral artery fenestration was 1. 22% (n =8),anterior communicating artery fenestration was 0. 61%(n=4),and middle cerebral artery fenestration was 0. 76% (n=5),respectively. The post-circulation fenestration was mainly convex lens type (66. 67%,n =17),the anterior-circulation fenestration was mainly fissure type (76. 47%,n=24),and there was significant difference (χ2=7. 411,P<0. 05). (2) In the 39 patients,22 complicated other vascular anomalies. Most of them were unilateral or bilateral fetal-type posterior cerebral arteries (n=10),and followed by aneurysms (n=5). The locations of 5 aneurysms were far from the fenestration,3 located in the communicating segment of internal carotid artery,1 in the top of basilar artery,and 1 in the M2 segment of bilateral middle cerebral arteries. Conclusion CTA can intuitively and clearly reveal the intracranial artery fenestration and other vascular anomalies. But there is no significant correlation between arterial fenestration and vascular anomalies.

Objective To investigate the alternation of left ventricular systolic function in patients underwent transcatheter aortic valve implantation operation(TAVI) by three-dimensional speckle tracking technology (3D-STI).Methods Totally 20 patients with severe aortic stenosis were enrolled.All the subjects underwent successful TAVI operation.The real-time 3D full volume datasets on apical four-chamber view were acquired on before,7 days and 1 month after TAVI.Left ventricular global longitudinal strain(GLS),regional peak systolic longitudinal strain(LS),regional peak systolic circumferential strain(CS) and regional peak systolic radial strain(RS),were analysed using off-line TomTec software,the differences among the three groups were compared.Results Compared with the preoperation,aortic valve blood flow velocity (AV),mean aortic valve pressure gradient(mPAG) of 7 days after operation decreased significantly.Threedimensional left ventricular ejecation fraction(3D-LVEF) among the patients whose 3D-LVEF under 50％had a remarkable increase and whose 3D-LVEF exceed 50％ before operation had no significant change,while 1 month after operation the 3D-LVEF had a significant improvement compared with the preoperational data regardless of 3D-LVEF under 50％ or not.The GLS and LS of all segments of 7 days after TAVI were higher than pre-operation(all P ＜0.05),and it had a further improvement 1 month after TAVI.Conclusions LV systolic function had improvement early after TAVI.3D-STI is a new,convenient way to detect the global and regional left ventricular systolic function of TAVI patients.

Objective To investigate the effects, and possible mechanism of action, of vasoactive intestinal peptide (VIP) on acute lung injury in a rodent model of endotoxic shock. Method Endotoxic shock was induced in Sprague-Dawley (SD) rats by intravenous injection of lipopolysacchaiide (LPS) at 10 mg/kg. Three groups (each group with 10 rats), were given injections of either normal saline (Control), LPS 10 mg/kg (LPS group), or LPS 10 mg/kg + VIP 5nmol (VIP). Samples were collected 6 hours after injection. Indices of lung injury including lung wet/dry weight ratio, protein concentration and neutrophil count in bronchoalveolar lavage fluid( BALF) were derived. Assays of TNF-α,IL-1β, IL-10 in serum and BALF were performed using ELISA. Light and electron microscopy were used to detect histopathological changes in lung tissues. Results The lung wet/dry weight ratio, protein concentration and neutrophil count in BALF were significantly raised in the LPS group compared to the Control group (P ＜ 0.05). These indices were significantly lowered in the VIP group compared to the LPS group, though not to the level of the control group. Concentrations of TNF-α, IL-1β, IL-10 in serum and BLAF also increased in the LPS group compared to the control group (P ＜ 0.0S). Levels of TNF-α and IL-1β were significantly lowered in the VTP group compared to the LPS group (P ＜ 0.05), while levels of IL-10 was significantly raised ( P ＜ 0.05). Histopathological changes due to lung injury were not as severe in the VIP group compared to the LPS group. CondusKms VIP plays a protective role during acute lung injury induced by endotoxic shock in rats. Its mechanism of action may be related to down-regulation of proinflammatory cytokines and up-regulation of anti inflammatory cytokines.