OBJECTIVE:To study the stability of Ondansetron hydrochloride glucose injection(OHGI).METHODS:The contents of Ondansetron hydrochloride and its related substances were determined with HPLC.The stability of the samples were tested by high-light exposure,accelerating experiment and room temperature storage.RESULTS:After exposure to high light,the content in OHGI slightly decreased but on other experiments,it was rather stable.CONCLUSION:This injection should be kept away from high light and may be stored for2years at room temperature.

Objective:To study the mental health status of middle school students in Three-Gorges area of Chongqing in order to provide theory support for mental health education. Methods:1 014 middle school students in Three-Gorges area were tested by SCL-90. Results:The occurrent rate of mental problems with students was 19.8%,of which the first three factors were hostility,compulsiveness and interpersonal sensitivity. Girls’ overall score and mean scores of interpersonal sensitivity, depression,anxiety and phobic anxiety were significantly higher than boys’. The overall score and factor mean scores of senior high school students were significantly higher than those of junior high school students’ except hostility and phobic anxiety factors. The mean scores of interpersonal sensitivity,hostility and phobic anxiety factors were significantly higher than the counterparts in the norms of middle school students,while the mean scores of somatization and anxiety factors were significantly lower than the counterpart in the norms of middle school students. Conclusion:The mental health status of middle school students in Three-Gorges area of Chongqing is poor,and mental health education should be enhanced by all of us.

Objective:To investigate the effect of liver ultrasonography and the security to rabbits with hydrogen peroxide(H 2O 2) affused by rectum.Methods:48 rabbits were divided into 4 groups according to different H 2O 2 concentrations,and each group was divided into 4 groups according to different H 2O 2 dosages. Each rabbit was affused with H 2O 2 by rectum,then the effect of liver ultrasonography was observed,and the damages to the tissues of rabbits were pathologically checked.Results:The liver structure could be clearly developed with 1% H 2O 2 10ml affused,and the liver gray value increased with the H 2O 2 concentration increased.The time from affusion to develop was shortened and the duration of high echo was prolonged.But at same H 2O 2 concentration,the time to develop was not significantly different with the H 2O 2 dosage increased,and the high echo was decreased more slowly.The average survival time of rabbits was significantly negatively correlated to the H 2O 2 concentration(?=-0.99),while the damage degree was significantly positively correlated (?=+0.99).Conclusion:H 2O 2 affusion can induce damage to tissues and microcirculation,while produce better liver ultrasound image,so it is important to chose suitable H 2O 2 concentration and dosage,to extend its clinical application.

After a description of the concept and characteristics of metaliteracy, the main institutions shouldering the task of metaliteracy education were summarized, including government and fund organizations, faculties, scien-tific research office, and teaching group. Of these institutions, library plays a major role in metaliteracy education since it is not only the main driving force of metaliteracy education and the institution to make,file and maintain the resources for metaliteracy education, but also is the organizer, coordinator and manager of metaliteracy teachers.

Objective To evaluate the relationships between serotypes of U.urealyticum intrauterine infection with outcome pregnancy and placental villus ultrastructural transform.Methods The placental tissues from 45 cases with spontaneous abortion,34 cases of high-risk pregnancy,including 6 premature delivery and 28 PROM patients(study group)and 51 normal pregnant patients(control group)were isolated,cnltured and performed.Serotypes of U.urealyticum were identified by a metabolic inhibition test.The positive cases placental tissue of U.urealyticum were preformed ultrastructural observation by electron microscope.Results Total positive rate 63.3%(50/79)in the study group,showing significant difference from that of control group(47.1%,24/51,P

Objective To explore the factors associated with quality of life(QOL)in patients with chronic obstructive pulmonary diseases(COPD).Methods Questionnaire was used to investigate 206 COPD patients,including demographic information,disease-related knowledge-attitude-practice and QOL scale.Results The total score of QOL in these patients was(64.70?14.78).There was statistically significant correlation between the quality of life and frequency of hospitalization in the past 2 years,marriage,education,course of disease by stepwise multiple regression analysis.Conclusion The quality of life in COPD patients is poor,especially in those who are spouseless,of longer disease course,of lower education degree,frequently hospitalized and insufficient for healthy practice.

Objective To search the status quo of students'thanatopsis in order to push focused education on terminal care to the nursing major students.Metheds To distribute home-made questionnaire to 268 nursing students.Results students who cannot talk about death normally account for 21.3 percent;who never considered death or unnecessary to consider death account for 12.9 percent of the total;who considered a lot account for 10 percent;who cannot handle terminally ill account for 74.3 percent;and who prefer self-suicide when suffered defeat account for 4.9 percent.Conclusion Nursing students have insufficient ideas of death,and they need to think deeply about the meaning of death and to nurture a positive outlook on death in order to get a correct terminal care education.

Objective To observe safety and effectiveness of Dezocine in postoperative analgesia of pediatric tonsillectomy and adenoidectomy by the continuous intravenous infusion of different doses,and to explore appropriate dosage of Dezocine for pediatric postoperative analgesia.Methods Elective tonsillectomy and adenoidectomy require-ments of postoperative analgesia in children 120 cases,they were randomly divided into A,B,C,D groups of 30 cases by using number table.After surgery patient -controlled intravenous analgesia(PCIA)two days,A,B,C groups were given Dezocine 0.2,0.3,0.4mg·kg -1 ·d -1 continuous intravenous infusion,D group received Sufentanil 1μg· kg -1 ·d -1 continuous intravenous infusion.Observed and recorded pain scores and sedation scores for postoperative 6h,12h,24h and 48h;recorded adverse reactions,pressing the number and effective pressing times of children within 48h after surgery.;recorded overall evaluation of postoperative analgesia of children and parents.Results A group at each time point pain score was significantly higher than B,C,D three groups,the difference was statistically significant (tAB =12.003,PAB =0.049;tAC =7.542,PAC =0.036;tAD =40.990,PAD =0.009);A,B,C three groups at each time point sedation score was significantly lower than D,the difference was statistically significant(tDA =3.894,PDA =0.030;tDB =5.020,PDB =0.039;tDC =36.103,PDC =0.016);D group of adverse reactions were significantly higher than A,B,C three groups,the difference was statistically significant(χ2DA =20.738,PDA =0.000,χ2DB =4.35,PDB =0.029,χ2DC =5.98,PDC =0.025);A group within 48h postoperative analgesia press times and the number of valid pressing were significantly higher than B,C,D three groups,the difference was statistically significant(tAB =3.003, PAB =0.036;tAC =5.720,PAC =0.031;tAD =37.157,PAD =0.015);B,C two groups of children and parents to evaluate postoperative analgesia overall satisfaction rates were 90.0%,93.3%,significantly higher than A 63.3%,D 60.0%,and the difference statistically significant (χ2AB =5.310,PAB =0.031;χ2DC =19.640,PDC =0.000). Conclusion Dezocine 0.3mg·kg -1 ·d -1 continuous intravenous infusion for pediatric tonsillectomy and adenoid-ectomy is safe and effective in postoperative analgesia and fewer adverse reactions,and should be promoted.

By using questionnaire method,We sent the questionnaires to 74 winners and 15 jury members of CMA-L'OREAL China skin/hair grant and analyzed the questionnaires that had been filled out by them.We got a better understanding on the issue of paper publications of the funded projects,and the judges,advices and overall feelings of winners and jury members on the grant.We analyzed why the grant has been highly appraised by the dermatologists,how the grant has promoted the research activities in the specific area,and what we should do to improve the grant management in the future.