Health Personnel ; psychology ; Humans ; Love ; Rare Diseases ; therapy

The paper described development characteristics of international hospital accreditation, and challenges faced by China's hospital accreditation.The author proposed for such accreditation,as that accreditation entities are the organizational support for building a permanent mechanism of hospital accreditation,and two organizational modes:the first is societies and associations of capacity to build accreditation organizations and the government to build professional hospital accreditation bodies,and the second is to build the assessors system.

Objective To investigate the clinical efficacy of acupoint application in treating senile hypertension of yin deficiency and yang excess type.Methods Sixty-six old patients with hypertension of yin deficiency and yang excess type were randomly allocated to treatment and control groups, 33 cases each. The control group took nifedipine controlled release tablets and the treatment group received acupoint application in addition. The quality of life score was recorded in the two groups before and after treatment. The clinical therapeutic effects were compared between the two groups.Results The total efficacy rate in reducing blood pressure was 90.0% in the treatment group and 84.8% in the control group; there was no statistically significant difference between the two groups (P>0.05). The total efficacy rate in improving the symptoms was 90.9% in the treatment group and 69.7% in the control group; there was a statistically significant difference between the two groups (P<0.05). There was a statistically significant pre-/post-treatment difference in the quality of life score in the two groups (P<0.05). There was a statistically significant post-treatment difference in the quality of life score between the treatment and control groups (P<0.05).Conclusions Acupoint application is an effective way to treat senile hypertension of yin deficiency and yang excess type. It can improve the quality of life in the patients.

Objective To comparatively analyze the results of the PT derivative method and the Clauss method for detecting fi-brinogen(Fib) by the automated coagulation analyzer and to explore their accuracy and clinical value .Methods Fib was detected in 156 blood samples selected from the patients in this hospital from March to May 2013 ,25 normal control samples and 13 positive samples of D-dimer (DD) by the TP derivative method and the Clauss method .Results The Clauss method and the PT derivative method by Sysmex CA-1500 coagulation analyzer had good repetitive rate in measuring Fib for 25 times ;when Fib<1 .0 g/L ,the results detected by these two methods had statistically significant difference (P<0 .05);when Fib in the range of 1 .0 -2 .0 g/L , 2 .1-3 .0 g/L ,3 .1-4 .0 g/L ,the detection results had no statistically significant difference between the two methods (P>0 .05);when Fib in the range of 4 .1 -5 .0 g/L ,the detection results had statistically significant difference (P<0 .05);when Fib>5 .0 g/L ,the detection results had statistically significant difference (P<0 .05);in 13 DD positive samples ,the detection results of the PT derivative method were significantly higher than those of the Clauss method with statistically significant difference (t=8 .530 , P<0 .05) .Conclusion The difference exists between the PT derivative method and the Clauss method for detecting Fib ,but the ac-curacy of the Clauss method is higher than its specificity ,the Clauss method should be the first choice for the clinical determination of plasma Fib .

Inherited metabolic disorder is a major class of clinical diseases with complexity and dififculty of being di-agnosed. Current clinical diagnosis has to rely on the metabolite analysis, gene analysis and enzyme activity (protein function) analysis of these three techniques. We analyse the features of the three diagnostic methods and clinical application of analysis, comparison and induction, to provide some experience and reference that help clinicians to better use of these three techniques. These three ways should be organically combined to form a diagnostic platform for inherited metabolic disorders.

Renal interstitial fibrosis is basically the common terminal pathway of various progressive renal diseases. Decrease of interstitial capillary density plays an important role in renal interstitial fibrosis. Endothelial progenitor cells can be induced to differentiate into mature vascular endothelial cells. They contribute to angiogenesis and angiopoiesis, and therefore may be a potential therapeutic approach for chronic kidney disease..

OBJECTIVE: To investigate the status quo and feature of the distribution rationality of licensed pharmacists in different regions in China in recent 2 years.METHODS: Using "per capita licensed pharmacists every ten thousand people" as index to contrast and analyze the distribution of licensed pharmacists.SPSS13.0 statistical analysis software was used to calculate the distribution Tail index(TI) of licensed pharmacists in the east,middle,and west regions of China taking population and GDP as weight.RESULTS: The distribution of licensed pharmacists in the east region in China was more intensive;TI was far greater when using population as weight than using GDP as weight,and all TI decreased in the past 2 years.CONCLUSIONS: The licensed pharmacists should be distributed rationally according to the practical demand on pharmaceutical care,and the government should intensify the education and training of licensed pharmacists in the middle and west regions of China.

OBJECTIVE:To investigate the status quo and the feature of licensed pharmacists in Hubei province to provide experimental reference and policy bases for the concerned governmental department in making decision about management regulations. METHODS: 486 licensed pharmacists who came to attend the continuing education were investigated by questionnaire survey and personal interview regarding their essential information, social approval, and attitude towards their profession etc. RESULTS: The obtained essential information of the licensed pharmacists in Hubei province revealed that the majority of them regarded that they failed to bring their role in into full play in their daily work and their social approval degree was low; as for attitude towards their profession, most of the interviewees responded that the evolvement of policy is the important factor to bring into the role of licensed pharmacists into full play, meanwhile they thought highly of the active role of continuing education. Different type of licensed pharmacists have different needs, to satisfy the diversified needs, a pertinent study is needed. CONCLUSION: The government should establish licensed pharmacists law as soon as possible to identify the legal position of licensed pharmacists and solve their orientation problem so as to bring their role into full play.

OBJECTIVE: To observe the effects of long-term administration of pioglitazone at different doses on the expression of glucose transporter-4(GLUT-4) of cardiac muscle tissue in rats and to discuss the possible mechanisms.METHODS: A total of 40 Wistar rats were enrolled,of which,10 were randomly assigned to normal control group(NC),and the other 30 were injected intraperitoneally with streptozotocin to establish diabetes mellitus(DM) rat model.After successful modeling,the rats were assigned to DM model group(DM,normal saline),high and low dose pioglitazone group(HP,LP;0.75,0.25 mg?kg-1?d-1).The NC groups received normal saline for 12 weeks.Blood glucose(BG) level before grouping(baseline level) and prior to death was determined by tail-cutting method.GLUT-4 level in cardiac muscle tissue and both protein and mRNA expression of AMPK? were determined by RT-PCR and western blot,respectively.RESULTS: As compared with NC group,the BG level in DM group was significantly increased but the expression of GLUT-4 and AMPK? decreased significantly(P