1.Effect of green bean (vigra radiata wilczek) on lipid peroxidation in vitro and in vivo
Ha Thi Nguyen ; Huyen Thi Thu Nguyen
Journal of Medical Research 2007;49(3):83-90
Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants
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Lipid Peroxidation
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2.Effects of Pilose Antler on Lipid Peroxidation and Antioxidative Enzymes in Cultured Liver Cells.
Kyung Soo NAM ; Yung Kyu KIM ; Cheorl Ho KIM ; Jin Young MOON ; Mi Jung CHOI ; Moung Won CHOI
Korean Journal of Immunology 1997;19(1):49-58
No abstract available.
Animals
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Antlers*
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Lipid Peroxidation*
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Liver*
3.The effect of aging on red blood cell memobrane lipid peroxidation in diabetic patients.
Hyung Joon YOO ; Sung Hee IHM ; Byung Tae KIM ; Yeon Bok CHANG ; Moon Gi CHOI ; Sung Woo PARK
Journal of Korean Society of Endocrinology 1993;8(3):281-286
No abstract available.
Aging*
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Erythrocytes*
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Humans
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Lipid Peroxidation*
4.The effects of the antioxidant capsule belaf on the antioxidant status and the lipid peroxidation in the plasma of the inseticide producing workers
Journal of Vietnamese Medicine 2003;283(4):23-27
43 people in 30 days before and after oral use of BELAF were studied. Results: blood red cell superocid dismistase (SOD) activation increased (691.7106.46 versus 984.23102.98 U/g Hb), white blood red cell glutathion peroxidase (GPx) and glutathion reductase (GR) had not any change obviously. The plasma total antioxidant state enhanced, MDA level decreased, ChE activetion enhanced. The study showed that BELAF could help to improve the state of antioxidation in blood red cell and in plasma of workers of chemical production
Pesticides
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Therapeutics
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drugs
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Lipid Peroxidation
6.Evaluation of Paraoxonase, Arylesterase and Malondialdehyde Levels in Schizophrenia Patients Taking Typical, Atypical and Combined Antipsychotic Treatment.
Mehmet GÜNEŞ ; Mehmet Akif CAMKURT ; Mahmut BULUT ; Süleyman DEMIR ; Aslıhan Okan IBILOĞLU ; Mehmet Cemal KAYA ; Abdullah ATLI ; Ibrahim KAPLAN ; Aytekin SIR
Clinical Psychopharmacology and Neuroscience 2016;14(4):345-350
OBJECTIVE: Human serum paraoxonase (PON1) prevents lipids from peroxidation and functions as an antioxidant mechanism. Malonyldialdehyde (MDA) is the final product of lipid peroxidation and can be used as an indicator of oxidative stress. The aim of this study was to investigate PON1, MDA, and arylesterase (ARY) levels in schizophrenic patients who are taking typical, atypical, or combined (typical and atypical) antipsychotic drug treatment, with respect to those of healthy controls. METHODS: We evaluated 41 patients (11 taking typical antipsychotics, 19 taking atypical antipsychotics, 11 taking combined anti-psychotics) and 43 healthy controls. RESULTS: MDA levels were higher in schizophrenic patients taking typical antipsychotics compared with healthy controls (p=0.001). ARY levels were higher in patients taking atypical antipsychotics compared with healthy controls (p=0.005). PON1 activity was similar in all groups. CONCLUSION: Our results indicate that treatment with typical antipsychotic drugs could be related to increased MDA levels; and antipsychotic medication may increase PON1 levels in schizophrenic patients.
Antipsychotic Agents
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Aryldialkylphosphatase*
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Humans
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Lipid Peroxidation
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Malondialdehyde*
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Oxidative Stress
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Schizophrenia*
7.Effects of Resveratrol Supplementation on Oxidative Damage and Lipid Peroxidation Induced by Strenuous Exercise in Rats.
Biomolecules & Therapeutics 2015;23(4):374-378
The purpose of the present study was to investigate the effects of resveratrol supplementation on oxidative damage and lipid peroxidation induced by strenuous exercise in rats. The rats were randomly divided into five groups: a sedentary control group, an exercise control group, and three treatment exercise groups administered increasing doses of resveratrol (25, 50, and 100 mg/kg body weight). Resveratrol was administered by oral gavage once daily for four weeks. At the end of the four-week period, the rats performed a strenuous exercise on the treadmill, and the levels of lactate dehydrogenase (LDH), creatine kinase (CK), malondialdehyde (MDA), 4-hydroxy-2-nonenal (4-HNE), and 8-hydroxy-2\'-deoxyguanosine (8-OHdG) were measured. The results showed that resveratrol supplementation had protective effects against strenuous exercise-induced oxidative damage and lipid peroxidation by lowering the levels of LDH, CK, MDA, 4-HNE, and 8-OHdG in the serum or muscle of rats. These beneficial effects are probably owing to the inherent antioxidant activities of resveratrol.
Animals
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Creatine Kinase
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L-Lactate Dehydrogenase
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Lipid Peroxidation*
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Malondialdehyde
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Rats*
8.Effects of light intensity on physiological and biochemical characteristics of Chrysanthemum morifolium at vegetative stage.
Qiaosheng GUO ; Yanru WANG ; Xianxiu ZHANG ; Miao JIN
China Journal of Chinese Materia Medica 2010;35(5):561-564
OBJECTIVETo study the effect of light intensity on physiological and biochemical characteristics of Chrysanthemum morifolium at the vegetative stage.
METHODThe dynamic response of physiological and biochemical indexes of Ch. morifolium were measured under different treatments (100%, 80%, 60%, 40% and 20% of the full sunlight) at the vegetative stage.
RESULTThe physiological and biochemical indexes of Ch. morifolium showed dynamic changes with the progress of growth and the increase of the treatment time. The soluble sugar content decreased when the light intensity reduced, and had a significant positive correlation with the light intensity. Soluble protein content rose firstly and fell later, malondialdehyde content increased, superoxide dismutase and catalase activity decreased initially and increased afterwards.
CONCLUSIONProper shading benefits the nitrogen accumulation of Ch. morifolium at the vegetative stage, and reduces the strength of stress condition. The suitable light environment for growth of Ch. morifolium at the vegetative stage is about 80%-60% of full sunlight and the optimum treatment time is 20-40 days.
Catalase ; metabolism ; Chrysanthemum ; physiology ; Light ; Lipid Peroxidation ; Superoxide Dismutase ; metabolism
10.A study of the pour blood and the oxygen metabolic in tissue for extra-artery fascia flap.
Jiaqi WANG ; Zhengyu GUAN ; Zhengjun LIU ; Ping ZHAO ; Min ZHAO ; Keming QI
Chinese Journal of Plastic Surgery 2002;18(3):155-156
OBJECTIVEThe aim of the work was to study the change for blood pour into the artery fascial flap and oxygen metabolic in tissue that knew the process of the flap.
METHODSWe do the artery fascial flap in the rabbit, then measured the skin capillary blood flow and the content of the MDA.
RESULTSThe content of the MDA rise when the blood flow descends in the flap, but it lives well.
CONCLUSIONSThat the content of the MDA rise as time the blood flow descend in the flap is a gradual process of the whole flap from tip to end, the flap will not appear necrosis until the MDA reach a rather degree.
Animals ; Fascia ; Lipid Peroxidation ; Male ; Rabbits ; Surgical Flaps ; blood supply