Lipid Droplets/metabolism* ; Bacteria ; Lipid Metabolism

No abstract available.
Lipid Metabolism* ; Peroxisomes*

In this review, lipid A, from its discovery to recent findings, is presented as a drug target and therapeutic molecule. First, the biosynthetic pathway for lipid A, the Raetz pathway, serves as a good drug target for antibiotic development. Several assay methods used to screen for inhibitors of lipid A synthesis will be presented, and some of the promising lead compounds will be described. Second, utilization of lipid A biosynthetic pathways by various bacterial species can generate modified lipid A molecules with therapeutic value.
Biosynthetic Pathways ; Lipid A*

No abstract available.
Diabetes Mellitus* ; Lipid Metabolism*

Lipid Metabolism ; MicroRNAs

Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants ; Lipid Peroxidation ;

33 patients ages of 38-78 in the hospital 175 participated to a study during 1/1998 5/1999. The research found that fenofibrate (lipanthy) at dose of 300 mg per day reduced obviously the total cholesterol, low density lipoprotein cholesterol and triglyceride. The more high level of these, the more effect of the drug was well tolerated and high safety. The side effects were mild and uncommon. The ure, creatinine, transaminase values were not changed by the drug and there were no complication of the gallblader stone
Lipid Metabolism ; Procetofen ; therapeutics

Fatty Liver ; drug therapy ; metabolism ; Humans ; Lipid Metabolism ; Lipid Peroxidation

Due to the observation, lipid disorder and AT III, PS, PC factors having an important role in the formation of clots in blood vessels, cerebral infarction. This study was carried out on 123 patients with cerebral infarction and 52 normal persons. Results: The normal values of AT III, PS, PC were equal to the normal values of foreigners: AT III: 115.88719.129%; PC: 108.36019.767%; PS: 109.93725.108%. The reduction of AT III, PS, and PC had the important role in cerebral infarction, especially the reduction of PS. This relationship had statistical meaning. There was relationship between AT III and triglyceride; PS and cholesterol; PS and LDL-C in patients with cerebral infarction
Cerebral Infarction ; Lipid Metabolism Disorders

No abstract available.
Animals ; Lipid Peroxides ; Mice* ; Skin*