1.Beyond the X's and Y's: A case of complete androgen insensitivity syndrome
Lipana Ma. Katherine R. ; Tanangonan Gladys G.
Philippine Journal of Reproductive Endocrinology and Infertility 2009;6():1-9
The Sex or sexuality is very complex subject. From a biological standpoint, the appearance of the external genitalia is only one parameter. Complete androgen insensitivity syndrome (CAIS), the most common form of male pseudohermaphroditism, embodies the multifaceted nature of this concept. Patients usually present with 46, XY karyotype with bilateral testes, female external genitalia, a shortened vagina, absent or rudimentary mullerian derivatives, normal breast development, and absent or scant pubic and axillary hair, as was the case in the patient presented herein. Prevalence ranges from 1 :20,400 to 1 :62,400 births. Its management often requires a multidisciplinary approach. Aside from addressing health risks, the psychosexual, social and ethical aspects of this condition should also be dealt with.
ANDROGEN INSENSITIVITY SYNDROME
2.The incidence of osteoporosis among Filipino based on calcaneal quantitative ultrasonography
De Guia Blanca C ; Lipana Ma. Katherine R
Philippine Journal of Reproductive Endocrinology and Infertility 2009;6(2):62-67
With the aging of the world's population, osteoporosis has emerged as a formidable health concern. Bone mineral density (BMD) is the only available clinical parameter for bone strength evaluation and is determined through the use of dual energy x-ray absorptiometry (DEXA), the gold standard for the diagnosis of osteoporosis, and peripheral DEXA, such as calcaneal quantitative ultrasonography (QUS). This is a cross-sectional, descriptive study which aimed to determine the prevalence of osteoporosis among Filipinos, based on T-scores utilizing calcaneal quantitative ultrasonography. Baseline bone mineral density of 20,726 Filipinos were gathered based on the T-scores from calcaneal quantitative ultrasound results. The WHO criteria standardized the classification of BMD based on T-scores. Results showed that 3 percent of Filipinos were osteoporotic, 22 percent were osteopenic, while the rest were normal. The female sex and advanced age were key determinants of osteoporotic risk wheareas geographic location appears to have no influence.
OSTEOPOROSIS
;
CALCANEAL
;
QUANTITATIVE
;
ULTRASONOGRAPHY