1.The clinical value of united detection of myocardial enzymes and troponin in the diagnosis of hypothyroidism
Qinghua GAO ; Ming WANG ; Linzhi GAO
Chinese Journal of Primary Medicine and Pharmacy 2012;19(5):707-708
Objective To discuss the clinical value of united detection of myocardial enzymes and troponin in the diagnosis of hypothyroidism.Methods 27 patients with hypothyroidism were chosen as the observation group.26 healthy volunteers were selected as the control group.CK-MB,LDH,AST,FT3,FT4,TSH,cTnT,cTnI were detected.Results The levels of serum AST,LDH,CK-MB of the observation group were significantly increased,the mean value was(52.67 ± 7.32)U/L,(265.23 ± 101.34)U/L,(26.75 ± 18.75)U/L respectively,which were significantly higher than the control group,the differences were statistically significant(P < 0.05).The c TnT and c TnI positive rate of patients in observation group were 70.4% and 81.5%,compared with the control group,the rates were much higher (P < 0.05).Conclusion The united detection of myocardial enzymes and troponin had high clinical value in the diagnosis of hypothyroidism.
2.Impacts of Leukoaraiosis on Short-term Outcome of Acute Cerebral Infarction
Linzhi GAO ; Aijuan ZHANG ; Suzhen WANG ; Yue SHEN
Chinese Journal of Rehabilitation Theory and Practice 2015;21(3):320-322
Objective To explore the impacts of leukoaraiosls (LA) on the short-term outcome of acute cerebral infarction. Methods 204 patients after acute cerebral infarction were reviewed from January 2012 to August 2014. They were divided into 4 groups according to the brain magnetic resonance imaging: cerebral infarction without LA (LA-0), and with LA (LA-1, LA-2 and LA-3). The Logistic regression analysis was applied with the short-term outcome of cerebral infarction as the dependent variable, and 16 possible factor as independent variables. Results There were 4 independent factors risk to the worse outcome of acute cerebral infarction, including LA, age, hypertension and cerebral infarction size (OR>1, P<0.05). Conclusion LA is an independent risk factors to the worse short-term outcome of acute cerebral infarction.
3.Survival state and fruiting characteristics of endangered medicinal plant Sinopodophyllum hexandrum plant in Tibet plateau.
Qi-Qiang GUO ; Chao GAO ; Hui-E LI ; Yan-Hui YE ; Yan-Ying HAN
China Journal of Chinese Materia Medica 2018;43(6):1104-1110
This study was carried out by the methods of typical plots investigation and laboratory test aiming at analyzing the survival state and fruiting characteristics of three Sinopodophyllum hexandrum populations in different environmental habitats. Meanwhile, it could provide scientific basis for enhancing wild population quantity recovery. The results showed that more population quantity grow in the habitats of large-area gap (Population A) and bushes (Population C) with a majority of the young individuals, while the minor-area gap (Population B) was the opposite. The development tendency of S. hexandrum populations would be the recession in the future. Spatial distribution pattern of populations was clumped at small scales but random at large scales. The indexes of population A and C, as fruit size,the quantity and quality of seeds,germ inability,were all superior to those of population B. Comparing the mainly environment factors of three populations, that favorable environmental factors for vegetative and reproductive growth of S. hexandrum populations were found,especially certain lighting intensity and fertile soil. Therefore, the favorable environmental habitats for S. hexandrum individuals growth could be artificial to promote the recovery and quantities of S. hexandrum populations in the future.
4.Developing Syllabus for Rare Breast Diseases Using the Integrated Multimodality of Case-/Problem-/Resource-Based Learning
Ru YAO ; Jiahui ZHANG ; Jie LIAN ; Yang QU ; Xinyue ZHANG ; Xin HUANG ; Lu GAO ; Jun ZHAO ; Li HUANG ; Yingzi JIANG ; Linzhi LUO ; Songjie SHEN ; Feng MAO ; Qiang SUN ; Bo PAN ; Yidong ZHOU
JOURNAL OF RARE DISEASES 2024;3(3):391-399
This study aims at establishing a teaching catalog and content for breast rare diseases and developing the syllabus for the breast rare disease using integrated multimodality of case-/problem-/resource-based learning (CBL+PBL+RBL). By conducting bibliometrics co-occurrence analysis, we collected 6291 articles on breast rare disease published from January, 1975 to June, 2024. Additionally, we retrieved the Textbook on Rare Diseases, the Catalog of Chinese Rare Disease, and Second Batch of Rare Disease Catalog and then decided the teaching content. From 16, 387 keywords, 1000 (6.1%) keywords were identified through co-occurrence analysis, including 50(0.3%) candidate diseases. These were classified into three categories: rare primary breast diseases, rare genetic mutation-related diseases associated with breast cancer, and rare systemic multi-system diseases involving the breast. From the candidate list, 20(0.1%) rare primary breast diseases were further selected for their notable clinical teaching significance, and significant multi-systemic diseases affecting the breast, whether related to gene mutations or not. Teaching plans were drafted using a diversified parallel teaching approaches, taking into account the characteristics of different diseases and the focus of different teaching methods. This study initiated the development of the teaching content for breast rare diseases and developed the teaching syllabus using the CBL+PBL+RBL integrated multi teaching model and targeting each rare breast disease for the critical point for teaching.