Primary tumor of the appendix is a rare disease entity of gastrointestinal malignancy. Most of them are discovered unexpectedly in an acute situation. The diagnosis of adenocarcinoma of the appendix is hardly made preoperatively. An unsuspected finding of appendiceal tumor during operation can cause confusion about appropriate management of the lesion. The prognosis of adenocarcinoma of appendix can be determined by Dukes' stage and is similar, stage for stage, to that of colorectal carcinoma. We experienced a patient with linitis plastica type of primary adenocarcinoma of the appendix, who complained right lower quadrant pain for twenty days. The patient underwent appendectomy only. The second curative operation could not be performed due to patient's condition.
Adenocarcinoma* ; Appendectomy ; Appendix ; Colorectal Neoplasms ; Diagnosis ; Humans ; Linitis Plastica* ; Prognosis ; Rare Diseases

Linitis plastica of the colon is an uncommon presentation of primary colorectal cancer. This entity of colorectal cancer is characterized by a diffuse infiltrating tumor with desmoplastic reaction and poor prognosis. Although widespread infiltration is the main feature of linitis plastica, the tumor extending to more than 2 segments of the colon is uncommon. We report a case of primary linitis plastica involving the entire colon, ileum and appendix. The clinical characteristics are discussed with a review of literatures.
Adult ; Appendiceal Neoplasms/*pathology ; Colonic Neoplasms/*pathology ; Humans ; Ileal Neoplasms/*pathology ; Linitis Plastica/*pathology ; Male

Early diagnosis of Borrmann type 4 advanced gastric cancer (AGC) is very important for improving the prognosis of AGC patients. Because there is no definite mass in most cases of Borrmann type 4 AGC, its accurate diagnosis via endoscopy requires an understanding of its pathogenesis and developmental process. Moreover, many people confuse linitis plastica (LP) type gastric cancer (GC), scirrhous GC, and Borrmann type 4 AGC. To distinguish each of these cancers, knowledge of their endoscopic and pathological differences is necessary, especially for LP type GCs in the developmental stage. In conclusion, diagnosis of pre-stage or latent LP type GC before progression to typical LP type GC requires the detection of IIc-like lesions in the fundic gland area. It is also crucial to identify any abnormalities such as sclerosis of the gastric wall and hypertrophy of the mucosal folds during endoscopy.
Diagnosis ; Early Diagnosis ; Endoscopy ; Humans ; Hypertrophy ; Linitis Plastica ; Prognosis ; Sclerosis ; Stomach Neoplasms*

Formaldehyde is a colorless irritating gas of pungent odor, which is used as a disinfectant, antiseptic, deodorant, tissue fixative and embalming fluid, It is used in the formation of resins, alcohols and acids, and in permanent press processes in the textile industry. If formaldehyde is swallowed, severe abdominal pain and vomiting is immediately noted. Corrosive gastritis can follow with diffuse ulceration, fibrosis and contracture of the stomach, resembling linitis plastica, which may be severe enough to require gastrectomy. We report a case of cicatricial contracted stomach due to the ingestion of formalin.
Abdominal Pain ; Alcohols ; Contracture ; Deodorants ; Eating* ; Embalming ; Fibrosis ; Formaldehyde* ; Gastrectomy ; Gastritis ; Linitis Plastica ; Odors ; Stomach* ; Textile Industry ; Ulcer ; Vomiting

Mantle cell lymphoma has a broad spectrum of endoscopic presentations, such as thick, rigid folds that are indispensible on air insufflation, superficial confluent ulceration, or a polypoidal mass protruding into the lumen. The exact diagnosis is difficult to make because the lesion is in the submucosal layer and inaccessible by biopsy. Lesions will often exfoliate necrotic cells which make interpretation difficult, or they may be too small in number and size and thus indistinguishable from anaplastic carcinoma. We report a case of mantle cell lymphoma with diffuse wall thickening of the whole stomach in a 51-year-old man. The series of endoscopic findings in this case support the role of differential diagnosis of linitis plasica type of advanced gastric cancer with mantle cell lymphoma.
Biopsy ; Carcinoma ; Diagnosis, Differential ; Humans ; Insufflation ; Linitis Plastica ; Lymphoma, Mantle-Cell ; Middle Aged ; Stomach ; Stomach Neoplasms ; Ulcer

Amyloidosis is a group of disorders characterized by the extracellular accumulation of insoluble, fibrillar proteins in various organs and tissues. It is classified, on the basis of the identity of the precursor protein, as primary, secondary, or familial amyloidosis. Gastrointestinal amyloidosis usually presents as bleeding, ulceration, malabsorption, protein loss, and diarrhea. However, gastric amyloidosis with gastric outlet obstruction mimicking linitis plastica is rare. We report a case of gastrointestinal amyloidosis with gastric outlet obstruction in a patient with ankylosing spondylitis. The patient was indicated for subtotal gastrectomy because of the aggravation of obstructive symptoms, but refused the operation and was transferred to another hospital. Three months later, the patient died of aspiration pneumonia during medical treatment.
Amyloidosis* ; Amyloidosis, Familial ; Diarrhea ; Gastrectomy ; Gastric Outlet Obstruction* ; Hemorrhage ; Humans ; Linitis Plastica ; Pneumonia, Aspiration ; Spondylitis, Ankylosing* ; Ulcer

Gastric syphilis has been reported to be relatively rare due to the difficulty in making a histological diagnosis. However if a serologic test for syphilis is positive and the ulcer regresses after anti-syphilitic treatment, it can be assumed that the gastritis was caused by Treponema Pallidum. The clinical diagnosis of gastric syphilis ranges from a benign ulcer to mimicking an infiltrative carcinoma or lymphoma. We encountered a 21-year-old woman who was referred for linitis plastica with epigastric pain and weight loss. The gastroduodenoscopy revealed multiple irregular gastric mucopurulent shallow ulceration and several nodular lesions mimicking linitis plastica. The appropriate antibiotic treatment resulted in a dramatic improvement and a complete reversal of gastric lesions. This recent case of gastric syphilis emphasizes the importance of remaining alert to the manifestations of syphilis.
Diagnosis ; Female ; Gastritis ; Humans ; Linitis Plastica ; Lymphoma ; Serologic Tests ; Stomach Neoplasms* ; Syphilis* ; Treponema pallidum ; Ulcer ; Weight Loss ; Young Adult

Adenocarcinoma is the most common pathologic diagnosis, representing >95% of colorectal cancers; mucinous adenocarcinoma (MA) accounts for 10-15% and SRC accounts for 0.1-2.4% of colorectal cancers. MA is defined as a tumor with > or =50% mucin. Patients with MAs have a poor prognosis, a higher proportion of peritoneal metastases, and present at a more advanced stage of disease. Linitis plastica involving the colon and rectum is usually a metastatic lesion from gastric cancer and other organs, such as the prostate, gallbladder, and breast. Primary linitis plastica of the colon is very rare. We managed a case of colon cancer occurring in a 19-year-old female with a histologic diagnosis of mucinous adenocarcinoma and morphologic features of linitis plastica. Herein we report a rare case of primary linitis plastica of the colon with a review of the literature.
Adenocarcinoma ; Adenocarcinoma, Mucinous ; Breast ; Colon ; Colonic Neoplasms ; Colorectal Neoplasms ; Female ; Gallbladder ; Humans ; Linitis Plastica ; Mucins ; Neoplasm Metastasis ; Prognosis ; Prostate ; Rectum ; Stomach Neoplasms ; Young Adult

Adenocarcinoma is the most common pathologic diagnosis, representing >95% of colorectal cancers; mucinous adenocarcinoma (MA) accounts for 10-15% and SRC accounts for 0.1-2.4% of colorectal cancers. MA is defined as a tumor with > or =50% mucin. Patients with MAs have a poor prognosis, a higher proportion of peritoneal metastases, and present at a more advanced stage of disease. Linitis plastica involving the colon and rectum is usually a metastatic lesion from gastric cancer and other organs, such as the prostate, gallbladder, and breast. Primary linitis plastica of the colon is very rare. We managed a case of colon cancer occurring in a 19-year-old female with a histologic diagnosis of mucinous adenocarcinoma and morphologic features of linitis plastica. Herein we report a rare case of primary linitis plastica of the colon with a review of the literature.
Adenocarcinoma ; Adenocarcinoma, Mucinous ; Breast ; Colon ; Colonic Neoplasms ; Colorectal Neoplasms ; Female ; Gallbladder ; Humans ; Linitis Plastica ; Mucins ; Neoplasm Metastasis ; Prognosis ; Prostate ; Rectum ; Stomach Neoplasms ; Young Adult

Primary gastric carcinoma is the most common cause of linitis plastica. Less frequently, metastatic gastric cancer from the breast, omental metastases and non-Hodgkin lymphoma involving the stomach have been reported to show similar radiographic findings as for linitis plastica. A metastatic gastric cancer from bladder cancer is extremely rare. We present an unusual case, the first to our knowledge, of gastric linitis plastica that resulted from a metastatic urothelial carcinoma of the bladder.
Diagnosis, Differential ; Humans ; Linitis Plastica/radiography/*secondary ; Male ; Middle Aged ; Stomach Neoplasms/radiography/*secondary ; Tomography, X-Ray Computed ; Urinary Bladder Neoplasms/*pathology