Objective To construct a design of northwest region army pilot health management based on modularization, which will provide basis for the management of army pilot health management. Methods Using Delphi method, three rounds of questionnaires were done within 30 experts, to build the design of northwest region army pilot health management based on modularization, which contained information module, management module, implementation module, update module and system flow module. Results The experts′ authority coefficient was 0.850, coefficient of determination was 0.865, and familiar coefficient was 0.870. The design of northwest region army pilot health management was determined to contain 5 first-level indicators, 19 secondary indexes. The coordination coefficients of the three level indicators were 0.624 and 0.543,respectively, and the contrast of coordination coefficients had statistical significance (P < 0.01). Conclusions The design of northwest region army pilot health management based on modularization constructed by Delphi method is proved to be scientific, reliable and practical, which can provide the basis for the health management of northwest region army pilot.

Objective To investigate the impact of high plasma LDL-C level with or without metabolic syndrome(MS) on the incidence of stroke in Chinese adults. Methods Totally 42 626 subjects (25 -75 years old) from Chinese National Health and Nutrition Survey in 2002 were stratified four groups based on plasma LDL-C level: < 2. 00 mmol/L group, 2. 00 -2. 50 mmol/L group, 2. 51 -3.31 mmol/L group, and ≥ 3.32 mmol/L group. The prevalence of MS (with 2005 International Diabetes Federation criteria) and stroke and the risk factors of stroke were compared among the four groups. Results ( 1 ) The prevalence of MS and stroke increased with rising of LDL-C level. The prevalence of MS in LDL-C≥3. 32 mmol/L group increased 2. 5 times (7, 9% vs 20. 1% ) as compared with that in LDL-C < 2. 00 mmol/L group and the prevalence of stroke increased 4. 2 times(0. 5% vs 2. 1% ), all P <0. 01. (2) In subjects with similar LDL-C level, the prevalence of stroke was significantly higher in a subgroup with MS than that without (P <0. 01 ). (3) After adjustment for age, sex and smoking, logistic regression analysis showed that both LDL-C level and MS were positively associated with the development of stroke; the odds ratio (OR) was 2. 35 and 3. 15 ( P < 0. 0001 ), respectively. (4) Compared with the subgroup of LDL-C < 2. 00 mmol/L without MS, OR for stroke in the subgroups of LDL-C 2. 00 -2. 50 mmol/L, 2. 51 -3. 31 mmol/L, and ≥ 3. 32 mmol / L without MS was 1.03, 1. 89, and 2.08, whereas the OR for stroke in the subgroups with MS and similar level of LDL-C was 4. 38, 5.23 and 6. 15 ; this indicated that the risk of stroke in subjects with MS increased by 3 - 4 times compared with subjects without ( P < 0. 0001 ). Conclusion Both high LDL-C level and MS are independent risk factors of stroke, but the risk of stroke will be further increased in the presence of high LDL-C level plus MS. It is suggested that combined intervention therapy of LDL-C and MS will play an important role in the prevention of stroke.

Objective: TO explore the effect of VEGF-C gene transfection on the expression of VEGF-C in human cervical carcinoma HeLa cells and the mechanisms of its anti-apoptosis effect. Methods: The con-structed pcDNA3.1(+)NEGF-C vector was transformed into human cervical cancer HeLa cells and was select-ed by G418. The changes in the expression level of VEGF-C mRNA and protein were determined by semi-quantitive RT-PCR and ELISA. HeLa cells with overexpression of VEGF-C were named as HeLa/S1. The expression level of NF-KB and bcl-2 mRNA was determined by RT-PCR in transfected cells. Results: After transfection by liposome, the VEGF-C mRNA level and the expression of VEGF-C protein in transfected cells were higher than those in the control groups. HeLa/S1 cell line was successfully established. In HeLa/S1 cells, the expression of NF-κB (2.06±0.09 vs 1.35±0.02 vs 1.38±0.02 P<0.05) and bcl-2 gene mRNA (2.02± 0.67 vs 0.41±0.06 vs 0.37±0.06, P<0.05) level were higher than those in the control groups. Conclusion: VEGF-C gene transfection by liposome can increase the expression of VEGF-C in human cervical cancer HeLa cells. NF-κB is stimulated and induces the overexpression of bcl-2 gene in HeLa/S1 cells.

Objective To investigate the indirect decompression effect of oblique lateral interbody fusion (OLIF) in the treatment of mild to moderate degenerative lumbar stenosis.Methods From October 2014 to November 2016,23 patients with mild to moderate lumbar spinal stenosis underwent OLIF combined with or without posterior pedicle screw fixation;9 males and 14 females with average age of 59.2±11.6 years old;8 cases at L3,4 segment and 15 cases at L4,5 segment.All cases were followed up for more than 6 months.Thin layer scanning of CT and two-dimensional reconstruction images were used to measure the vertical diameter and area of intervertebral foramen.Intervertebral disc height and spinal canal anteroposterior diameter were measured on median sagittal MRI sequence,and the anteroposterior diameter and the cross-sectional area of the spinal canal were measured on cross-sectional MRI sequence.The clinical effects were assessed by the visual analogue score (VAS) and the Oswestry disability index (ODI) for low back pain,lower limb pain and lower limb numbness.Results Compared with those measurements pre-operatively,the post-operative intervertebral disc height increased by 78.6％±13.4％.The post-operative left vertical diameter of intervertebral foramen increased by 36.7％±7.8％,and the post-operative left area of intervertebral foramen increased by 36.6％± 8.7％,and the post-operative right vertical diameter of intervertebral foramen increased by 40.7％±9.6％,and the post-operative right area of intervertebral foramen increased by 40.0％±8.9％.The post-operative anteroposterior diameter of sagittal spinal canal were increased 32.6％ ± 5.9％,and the post-operative anteroposterior diameter of cross-sectional spinal canal were increased 34.4％±6.8％,and the post-operative cross-sectional area of the spinal canal were increased 47.5％±7.2％.All of the differences were statistically significant between pre-operative and post-operative measurements.The VAS score for low back pain was 6.2± 1.7 pre-operatively,and 1.1±0.5 post-operatively.The ODI for low back pain was 81.2％± 18.2％ pre-operatively,and 6.1％±2.0％ post-operatively.The VAS score for lower limb pain was 5.6±1.4 pre-operatively,and 0.8±0.3 post-operatively.And the VAS score for lower limb numbness was 6.6±2.0 pre-operatively,and 3.4± 1.2 post-operatively.All of the differences were statistically significant between pre-operative and post-operative evaluations.Conclusion There were obvious radiological evidences and remarkable clinical effect of indirect decompression using OLIF technique in treatment of mild to moderate lumbar spinal stenosis at early post-operative stage.However further long-term follow-up studies with multicenter large sample were still needed.

Objective To explore the application effect of the health education path in the patients with multi-channel minimally invasive percutaneous nephrolithotomy .Methods Two hundred and four patients with percutaneous nephrolithotomy were chosen and divided into the observation group and the control group according to the random table , each with 102 cases.The observation group received the health education path , and the control group received the routine health education .The awareness rate of related knowledge and satisfaction were compared between two groups .Results The patient satisfaction was 100 .00% in the observation group , and was 97.06%in the control group, the difference was statistically significant (χ2 =14.864,P<0.05).The compliance rate of health education was 100.00% in the observation group, and was 93.14% in the control group, the difference was statistically significant (χ2 =17.236,P<0.05).Conclusions The health education path in the patients with multi-channel minimally invasive percutaneous nephrolithotomy standardizes the behavior of health education in nurses , and reflects the patient-centered philosophy , and is beneficial to improve patient satisfaction and the nurses'self-quality and quality of medical care .

Objective To establish nursing quality standard for parenchyma high explosive injury cured by VSD and discuss its rationality and maneuver ability.This study aimed to provide evidence and testing tools to evaluate nursing quality of VSD cured parenchyma high explosive injury.Methods We utilized theoretical research and clinical investigation,which applied Delphy of expert consultation method (21 experts and 2-rounds questionnaire and consultation) to quantitatively analyze the weight of all index and to establish standard of nursing quality care.Totals of 120 patients with parenchyma high explosive injury cured by VSD were divided into two groups randomly: experimental group ( sixty five cases ) and control group ( fifty five cases ) .The experimental group guided professional nursing and nursing quality assessment by the standard of nursing quality care, while the control group received routine. The difference had been compared on the length of hospitalization, the days of antibiotic utilization and the satisfaction of patients and families.Results The standard of nursing quality included 5 first level indexes and 40 second level indexes.In the experimental group, the length of hospitalization ( 14.90 ±0.60 ) d and the days of antibiotic utilization ( 8.32 ±1.44 ) d, respectively were lower than the control group[(18.90 ±1.30) d and (9.94 ±1.68) d respectively)], the differences were statistically significant (t=18.965,4.538, respectively;P<0.05).The satisfaction of patients and families were 96.9%and 98.5%in the experimental group while that of the control group were 83.6%and 89.1%respectively, the differences were statistically significant (χ2 =18.965,4.538, respectively;P<0.05). Conclusions The index system and clauses for different level of nursing quality standard acquired centralized comments from expert, so they have high reliability and provide an objective and quantifiable evidence for VSD cured parenchyma high explosive injury.

Objective To explore the prepare and implement the report of Clinical nursing path and its nursing application effects of micro-surgical wound infection, and regulate nursing management of VSD treatment. Methods A total of 50 patients received VSD treatment with clinical nursing path as experimental group during January to November 2013, and regression analysis 50 patients underwent VSD treatment and routine nursing during January to December 2012 as control group. All clinical data collected and analyzed. During VSD treatment, the index of health knowledge, sense of self-responsibility, and health duty in patients had been assessed effects in order to perfect and prove Clinical nursing path. Results The health knowledge, sense of self-responsibility, health duty, stress management, and patients satisfaction were (55. 47 ± 4. 41), (25. 53 ± 1. 60), (26. 12 ± 2. 21), (23. 96 ± 2. 14) and (3. 80 ± 0. 39) higher than these of the control group (P<0. 01). Conclusions Clinical nursing path is an effective method to treat wound infection of micro-surgery by VSD treatment, and can provide a quality nursing service, and enhance patients′satisfaction. It can acquire an excellence economic benefits and has a certain application value for nursing process management.

Objective To understand the current situation and demand of health education in the northwest army pilot, which will lay the foundation to construct a new health management model for the northwest army pilot.Methods A survey was conducted among a northwest pilot troop, in which 223 pilots were included. Self-designed questionnaires were used which was demonstrated by the Delphi method.Results The satisfaction degree of current health education was 39.2%. The health practice and the practice guidance can not meet their actual need, and the urgency degree they thought that the situation should be improved was 54. 45% and 37. 70%. There was a gape between the knowledge and skills, and the content of health education that they need most was the method to relieve fatigue (40.70%); As for the health education, they had demand of acquiring specialized knowledge, but the source and their self-learning ability were not enough, and they lack of professional guidance. Different content of different aspects of health education needs showed the characteristics of modular.Conclusions It is very necessary to apply modular health management into the northwest army pilot, and combined with different task situations, to divide modules with different emphasis into information module, management module, practice module, update module and series of modules. It is of great significance for guidance of the medical practice.

The survey on the hesitant status of rubella-containing vaccine (RCV) vaccination was conducted among 2 141 women of childbearing age in four provinces, Liaoning, Jiangsu, Zhejiang, and Anhui, from May 2017 to March 2018. Among the 2 141 study participants, a total of 38.21% (818) of women of childbearing age were aware of rubella and 21.25% (455) of women of childbearing age knew about RCV. Among the 455 women of childbearing age who were aware of RCV, 262 (57.58%) were willing to be vaccinated with RCV; 304 women of childbearing age (66.81%) tended to be vaccinated with RCV free of charge. Among the 193 women of childbearing age who did not want to be vaccinated or did not decide whether they preferred to be vaccinated with RCV, no one around them was vaccinated (89, 46.11%) and fear of vaccine safety (70, 36.27%) were the main reasons for hesitation to receive RCV.

The survey on the hesitant status of rubella-containing vaccine (RCV) vaccination was conducted among 2 141 women of childbearing age in four provinces, Liaoning, Jiangsu, Zhejiang, and Anhui, from May 2017 to March 2018. Among the 2 141 study participants, a total of 38.21% (818) of women of childbearing age were aware of rubella and 21.25% (455) of women of childbearing age knew about RCV. Among the 455 women of childbearing age who were aware of RCV, 262 (57.58%) were willing to be vaccinated with RCV; 304 women of childbearing age (66.81%) tended to be vaccinated with RCV free of charge. Among the 193 women of childbearing age who did not want to be vaccinated or did not decide whether they preferred to be vaccinated with RCV, no one around them was vaccinated (89, 46.11%) and fear of vaccine safety (70, 36.27%) were the main reasons for hesitation to receive RCV.