1.Design of POCT quality management system based on the Internet of things
Min ZHU ; Xiaoli CHEN ; Lingxiang ZHENG ; Liangjin ZHUANG ; Fuhui ZHANG ; Huiming YE
Chinese Journal of Clinical Laboratory Science 2017;35(6):405-408
Objective To design a POCT quality management system based on the Internet of things so as to standardize POCT quality management.Methods The existing problems in POCT quality management were analyzed.Taking portable blood glucose meters as an example,the quality management system of POCT-Internet of things was designed based on the all aspects of data acquisition,transmission,server management and storage,etc.Results The POCT quality management system based on the Internet of things and medical cloud technology was designed.The system could implement the management of POCT operators and devices,monitor the realtime quality control data and reports,and facilitate the administrators to analyze the quality problems in the whole process of POCT management.Conclusion The designed POCT quality management system based on the Internet of things has the theory feasibility.
2.Cost-effectiveness analysis of ferric carboxymaltose for treating iron deficiency anemia in adult Chinese patients
Wentao SUN ; Lingxiang ZHUANG ; Aixia MA
China Pharmacy 2023;34(22):2750-2755
OBJECTIVE To evaluate the cost-effectiveness of Ferric carboxymaltose injection in the treatment of iron deficiency anemia in adult Chinese patients. METHODS From the perspective of China’s health system, the partitioned survival model was constructed to simulate the treatment process and outcome of patients with iron deficiency anemia using ferric carboxymaltose and iron sucrose based on the ferric carboxymaltose phase Ⅲ clinical trial in China (NCT03591406). The study period was 1 year. Total costs and quality-adjusted life years (QALYs) were calculated for both treatment regimens, and incremental cost-effectiveness ratios were calculated. Scenario analysis was performed with different assumptions for efficacy parameters between 9th week and the end of 1 year, and from the perspective of China’s health system and the entire society. The sensitivity analysis was also performed. RESULTS In the basic analysis, compared with iron sucrose, incremental effectiveness of ferric carboxymaltose therapy was 0.007 QALYs, with an additional savings of 1 038 yuan per patient. Ferric carboxymaltose therapy was more effective and less costly, presenting an absolute advantage. The results of the scenario analysis and single-factor sensitivity analysis were consistent with the basic analysis. Probability sensitivity analysis showed that when the willingness-to-pay threshold was 1, 2, 3 times gross domestic product per capita in 2022, the probability of ferric carboxymaltose with a cost- effectiveness advantage was 88.2%,94.5% and 97.6%,respectively. CONCLUSIONS For Chinese adults with iron deficiency anemia, ferric carboxymaltose is a cost-effective treatment for iron deficiency anemia, compared with iron sucrose.