1.The diagnostic value of diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient values in children with cerebral infarction
Chinese Pediatric Emergency Medicine 2014;21(10):637-640
Objective To explore the diffusion-weighted magnetic resonance imaging (DWI) and apparent dispersion coefficient(ADC) value in cerebral infarction diagnosis and judgment of cerebral infarction outcome and staging of the value.Methods According to different stages,26 patients were divided into 3 phases,phase Ⅰ (6 ~72 h) had 11 cases,phase Ⅱ (4 ~ 10 d) had 12 cases,phase Ⅲ (10 d later) had 9 cases,of which 3 cases were reviewed,3 cases were recurrence of cerebral infarction.Each patient's MRI included T1 weighted imaging,T2 weighted imaging,DWI and ADC sequence scan image reconstruction,the ADC map obtained one regions of interest (ROI),and the mean ADC value of ROI were calculated,the average ADC value of the corresponding contralateral area were also calculated by the same method,and then the mean relative ADC value were calculated.Results DWI image of all cases showed high signal,11 cases showed high signal and 1 case showed low signal in phase Ⅱ.In phase Ⅲ,1 case showed normal signal and 1 case showed high signal,2 cases showed mixed signal,1 case were reduced,and the rest were all low signal.Compared with the contralateral corresponding region,the average ADC values were reduced in phase Ⅰ.The infarction average ADC values were 0.434 × 10 3mm2/s,0.653 × 10-3mm2/s,1.600 × 10-3mm2/s in phase Ⅰ,Ⅱ,Ⅲ respectively,and the average ADC values of contralateral corresponding region were 0.938 × 10-3 mm2/s,0.814 × 10-3 mm2/s,0.757 × 10-3 mm2/s respectively; the mean relative ADC values were (51.5 ±16.8)%,(79.2 ±30.0)%,(210.9 ±45.1)% in phase Ⅰ,Ⅱ,Ⅲ respectively (P < 0.05).Conclusion ADC value of cerebral lesions area and relative ADC value of the variation in time provides an objective basis for the diagnosis of DWI,contributes to timely and accurately determine the age of cerebral lesions and pathophysiology of the changes.
2.Application of Quality of Life Scale in Stroke(review)
Yongbin GUO ; Enyu WANG ; Linghong CAI
Chinese Journal of Rehabilitation Theory and Practice 2009;15(7):632-634
The development and evolution of the concept of quality of life(QOL)is introduced. Focuses on the quality of life scale in stroke patients with application and analyze the advantages and disadvantages of various scale.
3.Mobile stereotactic radiosurgical system
Linghong ZHOU ; Haoyu JIN ; Zhuoyu WANG
Chinese Medical Equipment Journal 2004;0(09):-
In this paper, the mobile stereotactic radiosurgical system, a new therapeutant for interstitial radiotherapy, is introduced. Its principle and initial clinical applications are also summarized
4.The study of digital X-ray data storage and communication
Xumei MO ; Zhuoyu WANG ; Linghong ZHOU
Chinese Medical Equipment Journal 1989;0(03):-
DICOM is an international standard in medical imaging and communication. This paper introduces the design of digital X-ray data storage and communication according to DICOM3.0 and emphasizes the implementation of such modules as the ones for communication and data storage.
5.Design and Speech Synthesis of CIS Strategy Based on Multi-channels for Cochlear Implants Speech Signal Processing
Linjing WANG ; Linghong ZHOU ; Zhongju XIAO
Chinese Journal of Medical Physics 2010;27(1):1659-1661,1680
Purpose:Cochlear implant is a sort of device which is used to restore normal heating for the profoundly deaf by electrical stimulation of the auditory nerve.Simulation of multiple channels demonstrates that the number of channels has significant influence on sound effect.Method:This paper reviews the Continuous Interleaved Sampling (CIS) strategy for cochlear implants,and simulates it in PC.The audible sound of cochlear implanter is synthesized,and preliminary analysis of the speech identification rate of CIS strategy in different channels has also been done based on the simulation.Result:CIS strategy using 6 or 8 channels can achieve better sound effect .Conclusion:Simulation results show that CIS strategy with envelope extraction and high number of channels can produce satisfactory speech synthesis effect
6.Effects of testosterone on norepinephrine release in isolated rat heart.
Xiaofei, WANG ; Yanzhou, ZHANG ; Jun, BU ; Linghong, SHEN ; Ben, HE
Journal of Huazhong University of Science and Technology (Medical Sciences) 2012;32(1):42-6
The effects of testosterone on norepinephrine release were investigated in the isolated rat hearts. Sprague-Dawley male rats (n=120) were randomized to testosterone and control groups. The rats in testosterone group were perfused with modified Krebs-Henseleit buffer containing different concentrations of testosterone (0.1, 1.0, 10.0, and 100.0 nmol/L, respectively). Myocardial ischemia was induced by globally stopping the perfusion flow. Exocytotic norepinephrine release was induced by electrical field stimulation at 5 V (effective voltage) and 6 Hz (pulse width of 2 ms) for 1 min. The overflow of norepinephrine was determined by high pressure liquid chromatography and electrochemical detection (HPLC-EC). Following acute ischemia, testosterone (1.0, 10.0 and 100.0 nmol/L) significantly reduced norepinephrine release (P<0.01), and the norepinepherine overflow was similar between the control and 0.1 nmol/L testosterone group (P>0.05). Electrical stimulation of the ventricle evoked norepinepherine release, and this was diminished by the perfusion with testosterone at the concentrations of 1.0, 10.0 and 100.0 nmol/L (P<0.01). It is suggested that testosterone suppresses ischemia- and electrical stimulation-induced norepinepherine release in the isolated rat hearts.
7.Analysis of the clinical effect of methylprednisolone in the treatment of patients with acute myelitis
Linghong WANG ; Juxiu HUANG ; Yuping LI ; Litong JIN
Chinese Journal of Primary Medicine and Pharmacy 2016;23(3):397-399
Objective To study the clinical curative effect and complication of methylprednisolone in the treatment of patients with acute myelitis.Methods 42 patients with acute myelitis were selected and randomly divid-ed into two groups,21 cases in each group.The control group was treated with dexamethasone,the observation group was treated with methylprednisolone.After treatment,the clinical parameters and effect of the two groups were com-pared.Results The total effective rate of the observation group was 85.7%,which was higher than 42.9% of the control group (χ2 =2.41,P <0.05).The improvement of muscle strength,restore micturition,walk on their own time in the observation group were (10.1 ±4.1)d,(7.1 ±3.4)d,(16.1 ±4.2)d,respectively,which were better than (23.4 ±7.3)d,(10.2 ±3.1)d,(22.6 ±7.3)d in the control group(t =3.15,1.69,1.97,all P <0.05).The total incidence of gastrointestinal reaction and complication rates of the observation group was 4.8%,which was lower than 19.0% of the control group (χ2 =6.37,P <0.05).Conclusion In treatment of patients with acute myelitis,methyl-prednisolone has good effect,which should be used in clinical practice.
8.Development of Long Pulse YAG Laser Treatment Machine
Zhenyu WANG ; Linghong ZHOU ; Chaomin CHEN ; Anyang WEI
Chinese Medical Equipment Journal 1989;0(03):-
Objective To develop a laser treatment machine for the benign prostatic hyperplasia(BPH),which can both avoid the transurethral resection symptoms(TURS) and rapidly remove the big BPH.Methods The machine adopted a long plus laser with 80W average power and 1000W peak value power in order to rapidly vaporize the neoplasm.Because of its high power,short operation time and small thermal penetraction depth,it could avoid the post-operation edema of the organ is resulted from the concretion of traditional continuous-wavelength YAG laser.The control system based on AT89C51 dominated the laser power,and meanwhile,it monitored the process to protect the machine.It was connected with the Hospital Information System(HIS) via RS232.Results The chicken breast tissues were irradiated with the sample machine under water,and the groove irradiated by laser was 4mm in width and 2.5mm in depth with the irradiation speed of 5mm/s.The arbonation of tissue surface was slight and the thermal damage to the adjacent tissues was the minimal.Conclusion This machine can rapidly vaporize the neoplasm with the minimal thermal damage to the adjacent non-irradiated tissues.It is desirable for the treatment of big BPH.
9.Application status in quo of field stretcher and its attachment
Feng ZHUO ; Zhiyuan WANG ; Guangjie CHEN ; Linghong ZHOU
Chinese Medical Equipment Journal 2003;0(10):-
This paper mainly discusses the development status in quo of field stretcher and its attachment with the history of field stretcher reviewed.The development trends of field stretcher in the future are also presented.
10.Method of building pencilbeam mode l for photon dose calculation
Haoyu JIN ; Qingwen LU ; Linghong ZHOU ; Zhiyuan WANG
Chinese Medical Equipment Journal 1989;0(01):-
Generally,pencil beam kernels for photon beam calculation are obtained through Monte Carlo calculations.In this paper,a pencil beam model is set up with a method of deconvolution from measured broad beam profiles.These profiles are usually available in a radiotherapy planning system.Furthermore,this method is applied to computing dose distributions at different sizes.Comparisons with measurements show that the accuracy of the calculated dose distributions fits well in a1%error interval in high dose gradient regions.