At present, there exist such problems in China as irrational distribution of medical resources, lack of market standards, weak awareness of competition and limitation of areas under medical insurance coverage. Yet with Chinas entry into WTO, there will be such severe challenges as change of the medical pattern and the pouring in of foreign medical institutions. In light of the circumstances, the medical industry in China should adopt the following measures: speeding up the reform of the medical and health system so as to enhance the competitive power; increasing the input of science and technology so as to strengthen the ability to innovate; and adopting the idea of the market so as to enhance the awareness of competition. In particular, attention should be paid to the change of needs of social groups, service orientation and manners on the part of domestic medical institutions should be studied, brand new concepts of service should be adopted, with respect shown to the rights of patients and a good image of each hospital should be created.

It’s a problem faced by most institutions how to make employment more standardized and legalized after Implement of Labor Contract Law of People's Republic of China. So the author studied employment mode and management mode of workforce out of organization primarily, and explored some problems produced after Implement of Labor Contract Law of People's Republic of China in order to find out perfect management method and employment mode. It has certain practical significance and guiding role.

Polymyositis (PM) and dermatomyositis (DM) are inflammatory myopathies and slowly advanced of unknown etiology that affect the skeletal muscles.With the advancement of the constant research on the disease and use of new technology,people have a penetrating realization about the pathogenesis. The disease is thought to be associated with autoimmune as well as nonimmune mechanism. By now, there is no overall summary on the newest advancement of the pathogenesis.We summarized the progress on the pathogenesis of the disease in order to make it more clear to physicians.

OBJECTIVE:To establish a method for the content determination of psoralen in Psoralea-pericarpium juglates lini-ment. METHODS:HPLC was performed on the column of Shim-pack VP-ODS C18 with mobile phase of methanol-water(60∶40, V/V)at a flow rate of 0.8 ml/min,detection wavelength was 246 nm,column temperature was 25 ℃,and injection volume was 20μl. RESULTS:The linear range of psoralen was 2.49-39.90 μg/ml;RSDs of precision,stability and reproducibility tests were lower than 2.00%;recovery was 97.23%-100.58%(RSD=1.17%,n=6). CONCLUSIONS:The method is fast,simple,accurate and re-liable,and can be used for the content determination of psoralen in Psoralea-pericarpium juglates liniment.

OBJECTIVE:To compare the licensed pharmacist system in China and the USA,and to provide reference for im-proving pharmaceutical care and promoting public safety of drug use in China. METHODS:The relevant literatures in recent 10 years were retrieved from CJFD and Wanfang database. The differences of legal status,access qualification,legal obligations and responsibilities of licensed pharmacists in the USA and China were compared,and suggestions on improving the licensed pharma-cists system in China were put forward. RESULTS & CONCLUSIONS:At present,the problems of licensed pharmacist system in China are mainly that the legal status is not high,the access threshold is low,the legal obligations and responsibilities are not clear. However,the licensed pharmacist system in the USA has been developed for a century and formed a relatively strict legal sys-tem. Model State Pharmacy Act promulgated by National Association of Boards of Pharmacy in USA has clearly defined the access qualifications,legal obligations and responsibilities of licensed pharmacists. The pharmacy acts of the states were enacted on its blueprint. In view of current problems in China,it is necessary to learn from the above experience of the USA to improve the legal status,access qualification,legal obligations and responsibilities of licensed pharmacists and the quality of pharmaceutical care.

The long-term results of 118 cases inoperable stage ⅢB non-small cell lung cancer were reported． All patients received CAP regimen or MVP regimen chemotherapy． 97 patients received radiotherapy, The results showed that 1-, 3-, 5- year survival rates were 53.4%, 19.5% and 8.5% respectively． The 3-, 5- year survival rate for squamous cell carcinoma were higher than those adenocarcinoma (P<0.05)． The 3-, 5- year survival rate for T4N0 M0 were higher than those T3 N3 M0,T4 N1～2 M0 and T4 N3 M0, (P<0.05～0.01)． There was no differencein the 3-, 5-year survival rate between CAP regimen and MVP regimen．

Objective To study the expressions and clinical significance of hypoxia inducible factor-1α( HIF-1α) ,vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptor-1 (VEGFR-1) and vascular endothelial growth factor receptor-2 (VEGFR-2) in the villi tissue of patients with missed abortion (MA) and early pregnant women. To explore the influence of hypoxia on placenta angiogenesis in missed abortion. Methods To de-tect the expression of HIF-1α,VEGF,VEGFR-1 and VEGFR-2 in the villi tissue of 35 cases of MA patients( re-search group) and 32 early pregnant women( control group) who underwent induced abortion surgery by immuno-histochemistry,and the results were statistical analysis. Results HIF-1α,VEGF,VEGFR-1 and VEGFR-2 were ex-pressed both in the villi tissue of research group and the control group. The expression of HIF-1α was higher in the research group than in the control group(P<0. 05). The expressions of VEGF,VEGFR-2 were significantly lower in the research group than in the control group ( P<0 . 05 ); the expression of HIF-1α was positively correlated with VEGF,VEGFR-1and VEGFR-2 in the control group, and the expression of HIF-1α was negatively correlated with VEGF and VEGFR-2 in the research group (P<0. 05),which had no correlation with VEGFR-1. Conclusion The expression of HIF-1α in the villi tissue of MA is up-regulated, the blood vessel formation of placenta decreases by adjusting the VEGF and VEGFR-2 genes transcription,which maybe is the important causes for MA.

After cataract,called posterior capsule opacification (PCO),is resulted from residual cortex or the proliferation of lens epithelial cells following extracapsular cataract extraction,and it is thought to be themost common complication and the main reason of eyesight decline after modern extracapsular cataract surgery.Lens epithelial cells remaining in the capsular bag after surgery play an important role in PCO.How to prevent and treat PCO is the focus of attention of eye scholars,and the major treating methods are administration of drug,laser and surgery.Recent years,scholars in home and abroad are interested in biological targeted therapy to prevent PCO,such as the topical application of antiproliferation of LECs,preparation of vector transfected immunotoxin and gene theropy etc.The research progress in recent years in the biological therapy of PCO were reviewed.

目的探讨脑瘫儿童康复治疗和教育的基本方法及其关系。方法将60例脑瘫患儿分为康复组、教育组和康复+教育组各20例,观察康复训练和教育效果。结果2年后,WeeFIM量表评定康复组和教育组为有效,而康复+教育组为基本恢复,且疗效优于康复组和教育组(P<0.05)。结论对脑瘫患儿分阶段、有针对性地采取医疗康复与教育相结合的方法,可获得良好效果。

Objective To investigate the rehabilitation training and education of one pair of twins with severe spasm type cerebral palsy(CP).Methods The rehabilitation training and education lasting 6 years was performed for one pair of twins(two girls with dysfunction in motion,one had basically normal intelligence,another one had poor intelligence).Results After rehabilitation training and education,the child with normal intelligence could walk by the help of crutch(initially,she could not sit independently)and study in a common learning environment with other child and gain a good performance record.Another child with low intelligence had very little improvement in motor function and intelligence.Conclusion By rehabilitation training and education,the children with cerebral palsy can minimize their disabled level on intelligence and recover their motor function.