1.Relationship among mental stress, coping style and self-efficacy beliefs of highland recruits
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(2):164-166
Objective To explored the mental stress situations and the relationship between mental stress, coping style and self-efficacy beliefs of the highland training recruits, and suggestions about mental health education of the recruits to be proposed.Methods The solider mental stress self-reported questionnaire, simplied coping style questionnaire, and generalized self-efficacy beliefs scale were administrated to 256 recruits from 3 companies have been randomly selected in a military training base of Qinghai province.Results The mental stress of the recruits included tension, sleepless, physical and mental exhaustion.The mental stress was significant positive correlation with negative coping style( r=0.349, P<0.01 ), and significant negative correlation with active coping style( r= -0.179, P<0.01 ), and with self-efficacy beliefs( r= -0.210, P<0.01 ).Meantime selfefficacy beliefs was significant positive correlation with active coping style( r = 0.532, P < 0.01 ).Negative coping style and self-efficacy beliefs could significantly predict mental stress.Conclusion Through these ways which improving the self-efficacy beliefs and instructing them to use suitable coping style may help the recruits reduce the mental stress.
2.Clinical analysis on early minimal enteral feeding′s prevention and treatment of feeding intolerance of very low birth weight infants
Chinese Journal of Primary Medicine and Pharmacy 2015;(5):715-716,717
Objective To investigate the effectiveness of early minimal enteral feeding′s prevention and cure of feeding intolerance of very low birth weight infants (VLBWs).Methods A total of 45 VLBWs from the neonatal intensive care unit(NICU) of the second people′s hospital of Shantou,were included,from 2011 Jan to 2012 Dec. 23 infants in the intervention group which were hospitalized in 2012,received early minimal enteral feeding (MEF), while 22 infants in the control group which were hospitalized in 2011,received routine feeding .The incidence of feed-ing intolerance of the two groups was observed .Results The incidence rate of feeding intolerance was 21.74%(5 cases) in the intervention group and 72.73%(16 cases) in the control group.The incidence rate of feeding intol-erance of the intervention group was lower than that of the control group obviously and the difference was statistical significance(P<0.05).The time to achieve full enteral feeding of the intervention group [(28.22 ±1.97)days] was significantly shorter than that of the control group [(34.23 ±3.10)days](P<0.05).Conclusion An early MEF is beneficial to reduce the occurrence rate of feeding intolerance ,achieve full enteral feeding sooner ,decrease the length of hospital stay and improve the life quality of VLBWs .
3.Influence of Anxiety and Depression in Digestive system Cancer Patients' Prognosis
Chinese Medical Ethics 1995;0(04):-
Objective:To study the effect of anxiety and depression in 46 digestive system cancer patients' prognosis.Methods:The differences of SDS mark?SAS mark and ≥ 50 mark percentage were compared between patients and common mould in nationwide adopting SDS and SAS,moreover the prognosis was compared between varying degrees of anxiety and depression in patients.Results:The SDS mark?SAS mark and ≥ 50 mark percentage in patients were obviously higher than that in common mould in nationwide;the patients with anxiety and depression had bad prognosis.Conclusion:The results suggest that anxiety and deprssion is common feeling in digestive system cancer patients and seriously influence the patients' prognosis,psychotherapy must be conducted and it may contribute to improve the patient's prognosis.
4.Surveillance of antimicrobial resistance in the clinical isolates from Chuzhou First Hospital, Anhui Province in 2015
Chinese Journal of Infection and Chemotherapy 2017;17(2):153-158
Objective To investigate?the?distribution?and?antibiotic?resistance?profile?of?clinical?isolates?in?2015?for?improving?antimicrobial treatment in Chuzhou First Hospital. Methods Bacterial identification and antimicrobial susceptibility testing were?performed?with?MicroScan?WalkAway?96?PLUS?bacterial?identification?system.?All?the?data?were?analyzed?by?WHONET5.6?software. Results A total of 1499 clinical isolates were collected during 2015, of which gram positive organisms and gram negative organisms accounted for 24.7% and 75.3%, respectively. Prevalence of MRSA among S. aureus was 37.0% and MRCNS among CNS 86.3%. All (100%) Staphylococcus and E. faecalis isolates were susceptible to vancomycin, daptomycin and linezolid. About 2.8% of the E. faecium isolates were resistant to vancomycin. All the Streptococcus pneumoniae isolates were penicillin-susceptible, mainly isolated from children. The prevalence of extended-spectrum beta-lactamases (ESBLs) positive strains was 52.9% in E. coli, 30.8% in Klebsiella spp. (K. pneumoniae and K. oxytoca) and 25.0% in P. mirabilis. The ESBLs-positive strains showed higher resistance rate than ESBLs-negative strains to most antibiotics. The percentage of the P. aeruginosa isolates resistant to meropenem and imipenem was all 29.4%. The percentage of the Acinetobacter spp. (A. baumannii accounted for 85.5%) strains resistant to imipenem and meropenem was 63.0% and 64.5%, respectively. Conclusions Antibiotic resistance is still serious in Chuzhou First Hospital in 2015, especially the emerging carbapenem-resistant Enterobacteriaceae, which is of great concern.
5.EFFECTS OF PROCYANIDINS EXTRACT FROM THE LOTUS SEEDPOD ON REACTIVE OXYGEN SPECIES AND LIPID PEROXIDATION
Zhiqun LING ; Bijun XIE ;
Acta Nutrimenta Sinica 1956;0(02):-
Objective: To study the effects of procyanidins extract from the lotus seedpod (LSPC) on active oxygen radicals and lipid peroxidation. Methods: (1) The scavenging effects of LSPC on O ?- 2 and ?OH was investigated by using chemiluminescence method; (2) The effects of different concentrations of LSPC on RBC auto oxidation and LPO formation of rat liver mitochondria in vitro were observed; (3) The LPO level of liver homogenates incubated with Fe 2+ and H 2O 2 in vitro were determined; (4) the mice were treated with a single intragastric feeding of 5% CCl 4 soya bean oil solution (10ml/kg bw) after seven days supplementation of LSPC 100, 200, 400 mg/(kg bw?d). The activities of SOD, GST and the level of LPO in liver and plasma of CCl 4 toxic mice were determined. Results: In vitro, LSPC 169.0mg/L or 105.3mg/L was shown to markedly scavenge O ?- 2 produced in xanthine/xanthine oxidase and ?OH in Fenton systems respectively, and could significantly inhibit the formation of liver LPO. In vivo, LSPC (100,200mg/kg) evidently reduced the level of LPO and increase the activities of SOD and GST. Conclusion: It suggests that LSPC may be used as an antioxidant and might effectively protect liver from the injury due to lipid peroxidation.
6.Analysis of health seeking behavior based on the planned-action theory in rural area of China
Journal of Peking University(Health Sciences) 2004;0(03):-
Objective:To explore the influencing factors on patients' health seeking behavior in rural China by employing the theory of planned action.Methods:Data from cross-sectional household-based health survey carried out in 2008 were used in the study.Correlations between outcomes and explanatory variables were studied by Logistic regression.Results:The studying population included 19 389 adult patients over the age of 15.Illness awareness,medical experience and structural restriction factors had strong effect on whether the patients chose medical service.Pepople in different socioeconomical status suffered different influences.Conclusion:Responding to the changing trend of health service demand among rural residents,we should recognize the differentiation and allocate the healthcare resources more rationally.
7.Clinical and pathological evaluation of conservative surgery for tubal pregnancy
Qian XIE ; Wenmeng LUO ; Ling LING ; Qin YIN ; Yu ZHANG
Chongqing Medicine 2014;(26):3416-3417,3421
Objective To conduct the clinical and pathological evaluation on the conservative surgery in tubal pregnancy . Methods 513 cases of tubal pregnancy in this hospital from January 2006 to December 2012 were divide into the conservative sur-gery group(A ,314 cases) ,samlpintectomy group(B ,43 cases) and the medication conservative treatment group (C ,156 cases) .The hospitalization days ,HCG negative-conversion time ,cure rate ,re-pregnancy outcome ,pregnancy during 1-year follow-up were com-pared between the group A and C .In group B ,43 cases of tubal pregnancy and accomplishing fertility were firstly performed the tubal linear incision in the pregnant site ,then the biopsy was conducted after stopping bleeding and finally the salpingectomy in af-fected side was performed .The tubal electric injury degree by the unipolar or bipolar electrocoagulation and the pathological changes under light microscope were observed .Results The hospitalization days ,symptom relief rate ,HCG negative-conversion time ,cure rate and re-pregnancy outcome had statistical differences between the group A and C (P<0 .05) .Conclusion The tubal conserva-tive surgery has short hospitalization time ,high symptom relief rate ,high cure rate and few complications .The pathological observa-tion shows the localized electrocoagulation injury .The pregnancy rate after surgery is high .
8.Analysis on monitoring results of Kaschin-Beck disease in Xi'an City in 2007
Long, XIE ; Wei, CHEN ; Ling, JIN
Chinese Journal of Endemiology 2008;27(5):511-512
Objective To investigate the status of Kachin-Beck diseage(KBD)in Xi'an and provide a scientific basis for decision-making in controlling the disease.Methods According to original disease data of KBD,children aged 7 to 12 were chosen to receive clinical and X-ray examination according to the KBD monitoring standard stipulated by the government in 6 villages of 3 countries in Xi'an.The local adults were elinically diagnosed and divided into different groups according to the clinical degrees and their ages.Resuhs Among 373 schod children who had clinical examinations,15 early cases were detected,and the detectable rate was 4.02%(15/373);Among 325 school childrenundergoning by X-ray,1 case was detected,and the detectable rate was 0.31%(1/325).In 5630 adults clinically tested,1402 patients were detected,the detectable rate was 24.90%(1402/5630).The patients distributed mainly in the population aged above 36 years old.Conclusions The situation of KBD control is still serious in Xi'an city.KBD monitoring and health education should be carried on.Furdher Tesearch on treatment methods and drug therapy should be performed.
9.Late-course and concurrent radiochemotherapy for advanced esophageal carcinoma
Mingli NI ; Yuhui WANG ; Ling XIE
Chinese Journal of Postgraduates of Medicine 2015;(11):807-809,810
Objective To compare the efficacy and toxicity of late-course concurrent radiochemotherapy and sequential chemoradiotherapy for advanced esophageal carcinoma. Methods Eighty-two patients with advanced esophageal carcinoma were randomized into two groups: 41 cases in late-course concurrent radiochemotherapy (LCRC) group were received two cycles chemotherapy and then underwent concurrent radiochemotherapy;41 cases in sequential chemoradiotherapy (SCR) group were received four cycles chemotherapy and then underwent radiotherapy. The regimen of chemotherapy in all cases:cisplatin 25mg/m2, 1-3 d;calcium folinate (CF) 150 mg/m2, 1-5 d;fluorouracil 375 mg/m2, 1-5 d, 21 d was one cycle. All patients were received the three-dimensional conformal radiation therapy, the total dose of radiation was same as 64 Gy. Results The short-term response rate was 85.4%(35/41) in LCRC group and 65.9%(27/41) in SCR group, they had significant difference ( P<0.05). The rates of acute radiation esophagitis that need treatment was 90.2%(37/41) in LCRC group and 87.8%(36/41) in SCR group, there had no significant difference (P>0.05). The l year, 2 years, 3 years survival rate were 68.3%(28/41) and 65.9%(27/41), 56.1%(23/41) and 51.2%(21/41), 46.3%(19/41) and 36.6%(15/41) respectively,the median survival time were 30.0 months and 26.0 months, there had no significant difference ( P>0.05). Conclusion The short-term efficacy of advanced esophageal carcinoma could be improved by the late-course concurrent radiochemotherapy.
10.Clinical significance of blood lactic acid,B-type brain natriuretic peptide and homocysteine in elderly acute cerebral infarction
Ling XIE ; Yanjie LIU ; Li LEI
International Journal of Laboratory Medicine 2014;(16):2154-2155,2158
Objective To investigate the clinical significance of the combination detection of blood lactic acid,B-type brain natri-uretic peptide(BNP)and homocysteine(Hcy)in elderly acute cerebral infarction.Methods The arterial and venous blood during a-cute onset stage,at 24,48,72 h after thrombolysis and at 12 h after fasting in 85 cases of acute cerebral infarction was collected for detecting blood lactic acid,BNP and Hcy,performing the dynamic monitoring analysis and the comparative observation with the healthy control group.Results The blood lactic acid,BNP and Hcy levels in the acute onset stage group and the recovery group were significantly increased compared with the healthy control group(P <0.05).The blood lactic acid,BNP and Hcy levels during the onset stage in the acute cerebral infarction group were(6.47 ±3.92)mmol/L,(100.52 ±48.96 )pg/mL and(48.96 ±15.13 )μmol/L respectively,which were significantly higher than those at 48,72 h of postoperative recovery,the differences between them were statistically significant(P <0.05).The blood lactic acid,BNP and Hcy levels during postoperative convalescence in the cere-bral infarction group were gradually decreased and declined to the minimal level until postoperative 72 h,which were(2.16±1.83) mmol/L,(33.61±10.42)pg/mL and(18.87±8.27)μmol/L respectively.Conclusion Blood lactic acid,BNP and Hcy are closely related with the occurrence and development of cerebral infarction,the joint detection of these three indicators provide a reliable ba-sis for the early diagnosis of elderly acute cerebral infarction.The active and effective treatment on the patient should be timely a-dopted and the dynamic monitoring should be performed in order to correctly assess the prognosis.