BACKGROUND:Biostimulation feedback treatment has been widely used for female stress urinary incontinence. The treatment principle is based on the electromyographic signal measured and the combination of biofeedback technique and electrotherapy technique.
OBJECTIVE:To evaluate the effect of biofeedback electrical stimulation in treatment of female stress urinary incontinence.
METHODS:Thirty female patients suffering from light or moderate stress urinary incontinence received biofeedback electrical stimulation for 4-8 weeks. The stimulation parameters were 60 Hz, 20-60 mA, 12-second feedback. The patients were instructed to contract pelvic floor muscle. The peak value of surface electromyography in pelvic floor muscular 2-second-rapid-contraction, mean value of pelvic floor muscular 10-second-contraction, mean value of the pelvic floor muscular 60-second-tolerance-contraction, and the rate of urine leakage were observed before and after treatment.
RESULTS AND CONCLUSION:The peak value of surface electromyography in pelvic floor muscular 2-second-rapid-contraction, mean value of pelvic floor muscular 10-second-contraction, and mean value of the pelvic floor muscular 60-second-tolerance-contraction were significantly increased after treatment, compared with before treatment (P<0.05). The rate of urine leakage was decreased obviously after treatment (P<0.05). Biofeedback electrical stimulation can significantly increase surface electromyography value of pelvic floor muscles during contraction, and is an effective treatment for female stress urinary incontinence.

After rapid development over the past few years,interventional neuroradiology has become an important branch of mini invasive neurosurgery,it brought new methods and approaches in the treatment of intracranial aneurysms,intracranial arteriovenous malformations,duramater arteriovenous fistula,ischemic cerebrovascular diseases and so on.Particularly,the technique has also made impressive headways in the embolization of intracranial wide necked aneurysms and development of new embolizing materials.To accelerate its development,more emphasis should to be put on the basic theories of interventional neuroradiology,and more efforts should be made to develop new techniques,new materials and new equipments in the area.Finally,doctors should be trained and the manipulation regulations and quality control system should be established.

OBJECTIVE To investigate the characteristics of nosocomial infection,bacterial strains and antimicrobial resistance to provide references for the clinical application of drugs.METHODS Using the combined methods of initiative monitoring and recalling system to carry on the clinical informations′statistics,the analysis and the judgment for the 912 inpatients in the rehabilitation center from Jan Oct,2007 to oct,2008 were undertaken.RESULTS The rate of nosocomial infection was 16.9%,the infection site was in mainly respiratory tract,the next was urinary tract.The pathogens were mainly Gram-negative bacteria,in whith Escherichia coli,Klebsiella pneumoniae,and Pseudomonas aeruginosa were the top three.The resistance rate of 34 strains of E.coli to ampicillin was up to 83.0% and to quinolones was 70.0%.13 strains of P.aeruginosa were sensitive to imipenem and meropenem.The resistance rate of K.pneumoniae to the common drug was raising,to piperacillin and aztreonam was 90.0%.CONCLUSIONS The antibiotics must be choosen rationally to enhance effectiveness,reduce side effect and make the resistant strains decreasing in number.

Therapy of invigorating qi and ascending qicollapse,created by ZHANG Xi-chun,is a basic rule for curing the syndrome of sinking of qi.Shengxian Decoction is the classic recipe for curing the syndrome of sinking of qi.During studying with my tutor,Professor CAO Hong-xin,I witnessed the good efficacy of such therapy on a variety of diseases such as arrhythmia,myasthenia gravis,respiratory disease and female dysuria and so on.This article is to summarize and explain the therapy with some examples.

On inheriting the doctrines of Li Dong-yuan's'Internal damage of spleen and stomach causes diverse illnesses'and YE Gui's moistening stomach-yin etc.,Professor LU Zhi-zheng elaborates their academic thoughts further and proposes the core of spleen and stomach regulation in modern times——'cotrolling the center,operating four sides,keeping happy emotion,regulating ascending and descending,considering moistening and dryness,normalizing food and drink'.He does not only apply spleen and stomach to treat spleen and stomach illness but also treat vertigo,thoracic obstruction,cardialgia,apoplexy,liver and kidney diseases,rheumatosis and so on,which are all effective.However,as times,diets and living habits are changing,as well as social environment is different,the spleen and stomach diseases,which are caused by people's unhealthy diet,irregular work and rest,overworking and high spiritual pressure of work in this modern society with profound food and clothing and highly developed material civilization,has changed greatly from the spleen and stomach theory in Dongyuan times.In this case,Professor LU experiences that the reason for injured spleen and stomach in modern society has its unique pathogenic factor,thus sets up the etiology and pathogenesis for spleen and stomach of internal injury in the new times.

Adult ; Aged ; Automobile Driving ; Female ; Helicobacter Infections ; epidemiology ; Helicobacter pylori ; Humans ; Male ; Middle Aged ; Peptic Ulcer ; epidemiology ; microbiology ; pathology ; Retrospective Studies

Inherited epidermolysis bullosa (EB) is a group of hereditary skin diseases characterized by increases in skin brittleness and being prone to skin blisters or erosions when the skin is exposed to slight friction or injury. At present, it is classified into four types, namely EB simplex, junctional EB, dystrophic EB and Kindler syndrome. An onion skinning approach is recommended for the diagnosis of inherited epedermolysis bullosa, in which, immunofluorescence mapping is performed firstly, and causative genetic loci are then determined through detection of relevant genes. In its treatment, skin care should be intensified, and medical or surgical treatment may be used to alleviate symptoms. Further development of cell?, protein?and gene?based therapies is expected to bring hope to patients via realization of timely prenatal diagnosis and avoidance of adverse consequences.

As one of active immune effector molecules,immunoglobulins play an important role in the pathogenesis,diagnosis and treatment of autoimmune bullous diseases.Human immunoglobulins can be divided into 5 categories,including IgG,IgA,IgM,IgD and IgE,and all of them participate in and play different roles in the pathogenesis of autoimmune bullous diseases except IgD.IgG can induce the formation of blisters by activating complements and leukocytes as well as by releasing proteolytic enzymes,and different subtypes of IgG differ in biological activities.IgA can cause granulocyte migration and lead to the formation of blisters and pustules.IgE is associated with urticaria-like erythema and eosinophil infiltration.IgM is usually seen in Brazilian pemphigus foliaceus.These findings may provide new ideas for the diagnosis and treatment of autoimmune bullous diseases.

Objective To explore the effect of acupuncture combined with rehabilitation training on unilateral spatial neglect (USN).Methods One hundred stroke patients with USN were randomly divided into a treatment group (n=50) and a control group (n=50).Both groups were treated with routine rehabilitation training for 4 weeks,while the treatment group was additionally treated with acupuncture.Before and after the treatment,the degree of USN was evaluated in both groups along with the Fugl-Meyer assessment,the modified Barthel index and the incidence of shoulder pain.Results No significant differences were found between the 2 groups in any of the measurements before the treatment.After the treatment the incidence of shoulder pain in the treatment group was significantly lower than that in the control group.All the other measurements were significantly higher in the treatment group than in the control group.Conclusion Acupuncture combined with rehabilitation training can significantly improve the symptoms of unilateral spatial neglect,improve motor function in a hemiplegic limb and improve performance in the activities of daily living.

AIM: To explore the effects of oxidized low density lipoprotein (OxLDL) and one of its component— lysophosphatidylcholine (LPC) on cholesterol efflux from mouse macrophage foam cells. METHODS: (1) Cholesterol efflux induced by apoAI from mouse peritoneal macrophage foam cells loaded with OxLDL or acylated LDL(AcLDL) was measured. (2) Cholesterol efflux induced by LPC and apoAI from macrophage foam cells separated from normal or apoE gene deficient (E 0) mouse loaded with AcLDL were measured. RESULTS: (1) When the macrophage foam cells were incubated with apoAI, cholesterol efflux from AcLDL-induced macrophage foam cells increased significantly compared to that of OxLDL-induced macrophage foam cells. (2) LPC promoted cholesterol efflux from macrophage foam cells in relation to both dosage and time. When LPC was incubated with E 0 mouse macrophage foam cells, the released cholesterol mass was significantly lower than that of normal mouse macrophage foam cells. It was also found that cholesterol efflux induced by apoAI normally occurred in E 0 mouse macrophage foam cells. CONCLUSIONS: (1) OxLDL accumulated cholesterol in macrophages and impair cholesterol efflux. (2) LPC induced cholesterol efflux from macrophage foam cells, which may occur via apoE pathway.