1.First visit for hoarseness: a rare case of a fish bone in paraglottic space.
Li-bo DAI ; Ling LING ; Yong FU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2009;44(4):334-334
Foreign Bodies
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complications
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diagnosis
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Glottis
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Hoarseness
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diagnosis
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etiology
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Humans
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Male
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Middle Aged
3.DNA methylation in Barrett esophagus and esophageal adenocarcinoma
Bo LI ; Zhiqiang LING ; Weimin MAO
Journal of International Oncology 2012;39(6):439-442
In recent years,a large number of researches show that the tumor related gene promoter hypermethylation is an important reason of esophageal adenocarcinoma and closely associated with the differentiation,invasion,metastasis,staging and prognosis of tumors.It might be used as a neww target for the clinical detection and therapy of esophageal adenocarcinoma.
4.Changes of expressions of axon guidance molecule Sema3F and its receptor Np2 in hippocampus of temporal lobe epilepsy rat
Xueqian YUAN ; Bo XIAO ; Ling LI
Journal of Clinical Neurology 2001;0(05):-
Objective To investigate the changes of expressions of axon guidance molecule Sema3F and its receptor Np2 in hippocampus of temporal lobe epilepsy(TLE)rat.Methods Rats were injected with Lithium-chloride,Pilocarpine intraperitoneally to establish TLE model.The Sema3F mRNA,Np2 mRNA and protein in areas CA1,CA3 and dentate gyrus(DG)of hippocampus at different time were detected by immunohistochemistry and in situ hybridization for TLE models.Further,they were compared with normal control group.Results Compared with normal control group,the expressions of Sema3F mRNA,Np2 mRNA and protein in areas CA1,CA3 significantly decreased(P
5.Analysis of Allergens Detection in Asthmatic Infants and Young Children
xiao-bo, ZHANG ; li-bo, WANG ; ling-en, ZHANG
Journal of Applied Clinical Pediatrics 2004;0(11):-
Objective To analyze the allergens detection in asthmatic infants and young children. Methods The specific IgE test and allergens screening test were conducted in 243 infants and young children with whooping diseases including asthmatic bronchitis, asthmatic pneumonia and asthma by skin prick test and Pharmacia UniCAP test. Results 1. Food allergen was the allergen detection most frequently in infants(P = 0.03). The proportion of aeroallergens increased significantly with age (positive rate:67. 2%). Milk and egg white was the main food allergen detection in infants and young children,and the main aeroallergen detection was house dust mite. 2. The allergen - specific IgE test using UniCAP test system was more accurate than skin prick test. Conclusions The infants are more susceptible to food hypersensitivity; the increasing opportunity of aeroallergen exposure may lead to a higher prevalence of aeroallergens in young children. UniCAP system is more accurate than other methods.
6.Current-status survey on job stressor and exhaustion among nursing staff in the catheter room of grade Ⅲ- A general hospitals
Ying QIN ; Li XIA ; Ling FANG ; Bo LI
Chinese Journal of Practical Nursing 2011;27(13):12-15
Objective To survey the current status of job stressor and exhaustion among nursing staff in the catheter room of grade Ⅲ-A general hospitals and to look for regularities.Methods 178 nursing staff coming from catheter room,operating room,and outpatient department of Shenzhou Hospital and Fengtian Hospital accepted questionnaires of Chinese Nursing Stressor Scale and Exhaustion Scale in Spring 2010.Results Chinese Nursing Stressor Scale indicated that scores of subitem and total score of job stressor in the catheter room were significantly higher than those in the outpatient department; however,there were no significant differences in scores of subitem and total score of job stressor between catheter room and operating room.On the other hand,Exhaustion Scale showed that scores of emotional exhaustion and job unconcerned feeling in the catheter room were significantly higher than those in the outpatient department,but scores of job achieved feeling in the catheter room were significantly lower than those in the outpatient department.There were no significant differences in Exhaustion Scale between catheter room and operating room nurses.Conclusions Job stressor and exhaustion were serious among nursing staff in the catheter room of grade Ⅲ-A general hospitals,which should cause the attention of management department.
7.Manual reduction for radius head fracture with radioulnar synostosis and elbow disloction: a case report.
He-bo LIU ; Ling-li WEI ; Chang-bao ZHOU
China Journal of Orthopaedics and Traumatology 2015;28(6):535-537
Adult
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Elbow Joint
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injuries
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Female
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Humans
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Joint Dislocations
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therapy
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Musculoskeletal Manipulations
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Radius
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abnormalities
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Radius Fractures
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therapy
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Synostosis
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therapy
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Ulna
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abnormalities
9.Median effective target effect-site concentration of sufentanil inhibiting responses to insertion of laryngeal mask airway when combined with propofol in elderly patients
Ling LIU ; Bo LI ; Jian SUN ; Guoyi LYU
Chinese Journal of Anesthesiology 2014;34(7):824-825
Objective To determine the median effective target effect-site concentration (EC50) of sufentanil inhibiting responses to insertion of laryngeal mask airway (LMA) when combined with propofol in the elderly patients.Methods ASA physical status Ⅰ or Ⅱ patients,aged 66-75 yr,with body mass index of 19-30 kg/m2,scheduled for elective transurethral resection of prostate under general anesthesia,were included in this study.Anesthesia was induced with propofol given by target-controlled infusion.The initial target effect-site concentration (Ce) of propofol was 1 μg/ml,and the Ce was increased by 0.5 μg/ml every 1 min until it was increased to 2 μg/ml and maintained at this level for 5 min.Sufentanil was simultaneously administered by target-controlled infusion.The target Ce of sufentanil was 0.3 ng/ml in the first patient.The concentration of sufentanil was determined using the modified Dixon's up-and-down method.After the patients lost consciousness,LMA was inserted after the target effect-site and plasma concentrations were balanced.The insertion response was defined as positive when MAP and HR increased by 20% of the baseline value within 5 min after insertion of LMA.The Ce of sufentanil was increased/decreased in the next patient if the insertion response was positive or negative.The ratio between the two successive concentrations was 1.2.The EC50 and 95 % confidence interval of sufentanil blunting responses to insertion of LMA was calculated using Probit analysis.Results When combined with propofol,the EC50 (95% confidence interval) of sufentanil blunting responses to insertion of LMA was 0.160 (0.130-0.188) ng/ml.Conclusion The EC50 of sufentanil inhibiting responses to insertion of LMA is 0.160 ng/ml when combined with propofol in the elderly patients.
10.Pharmacokinetic Studies of Sinomenine by Blood Microdialysis Technique
Jiajun LING ; Yan WANG ; Bo XIE ; Rui LI
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(05):-
[Objective] To explore the feasibility and advantages of blood microdialysis technique for the pharmacokinetic study of sinomenine. [Methods] In this study, rats served as the experimental subjects and sinomenine was administered to the rats by intravenous injection. With microdialysis technique for blood sampling, the blood concentration of sinomenine was determined by high performance liquid chromatography (HPLC) and the associated pharmacokinetic parameters were analyzed by 3p97 program. [Results] The pharmacokinetics process of sinomenine in rats presented as the two-compartment model. The half-life of distribution phase was 10.98min and that of elimination phase was 44.71 min. [Conclusion] It is feasible to study pharmacokinetic parameters of sinomenine by using blood microdialysis technique. In comparison with the traditional technique, blood microdialysis technique is superior to the examination of drug blood concentration .