[Objective] To discuss the opportunity and method of the posterior route operation in the upper-middle thoracic fracture to resume the thoracic vertebral normal sequence、decompression completely and reconstruction immediate stability as soon as possible,so as to relieve pressure to spinal cord and nerve and avoid the secondary trauma of spinal cord and nerve and blood vessel and patients can do rehabilitation.[Method]Seventeen cases of the patients with upper-middle thoracic vertebral fracture were operated on with posterior route early decompression、fusion、internal fixation under general anaesthesia.There were 17 cases including male 11 and female 6 with the ages from 18 to 53 years(average 33.8 years).The injury reason: 7 cases as traffic accident,10 cases as falling from high altitude.The time from trauma to hospital were 1 hr.to 72 hrs.(average 15.4 hrs.).The injured segment of vertebral: T5～T10 segment,T5 2 cases,T6 6 cases,T7 5 cases,T9 4 cases,T10 2 cases.The function evaluation of spinal cord: 10 cases with incompletely neurological defect,7 cases with completely neurological defect.[Result]All patients were followed for 6~27 months(average 13.5months).The thoracic vertebra restoration were contentment and bone fuse were obtained in 12 weeks after operation.10 cases with incompletely neurological defect got improved postoperatively and 5 cases activity normolly.7 cases with completely neurological defect got improved of numbness and pain.[Conclusion]The upper-middle thoracic vertebral fracture can be operated early and the outcome are contentment.

Objective To study the inhibition effects of 10-hydroxycamptothecinc and low molecular weight heparins on human hepatocellular carcinoma(HCC)in nude mice.Methods Metastatic model of HCC was established in nude mice.The model mice were randomly divided into 4 groups:the control group,10- hydroxycamptothecinc group,low molecular weight heparins group,and combined treatment group(10-hy- droxycamptothecinc and low molecular weight heparins).Tumor sizes,tumor inhibition rates,tumor metas- tases,intratumoral microvessel density(MVD),CD_(31)and AFP were evaluated.Results In comparison with the control group and the 10-hydroxycamptothecinc group,the tumor sizes of the low molecular weight heparins and the combined treatment group were significantly smaller;the tumor inhibitor rates were 0 versus 76.6%, 79.8%,94.1%;MVD were 21.1?6.5 versus 17.2?3.1,7.1?2.3 and 4.8?1.8;CD_(31)were 31.7?6.1 versus 26.2?5.2,20.9?4.7 and 19.5?2.4;the incidence of liver metastasis was 80% versus 70%,20% and 10%;lung metastasis was 70% versus 60%,20% and 10%;the peritoneal metastasis was 90% versus 60%,30% and 30%.AFP were(121.9?31.4)ng/ml versus(56.2?37.9)ng/ml,(75.6?28.7)ng/ml and(20.7?12.9)ng/ml. Inhibiting effects of growth and metastasis of HCC in 10-hydroxycamptothecinc group,low molecular weight heparins group and combined treatment group were significantly different from those of the control group(F= 9.074,P

Abundant experiences have already been accumulated in treatment of stroke with acupuncture. Development of rehabilitation theory also brings unprecedented opportunity and challenge to acupuncture. Combined with the modern rehabilitation theory and practice, it is very helpful to deepen the understanding on treatment of acupuncture for cerebral apoplexy and enhance the therapeutic effect in clinic by studying the mechanism of acupuncture treatment, opportunity of intervention, selection of acupoints, needling manipulations and quantity of stimulations etc. Through analysis on the necessity and the way of combination of acupuncture and modern rehabilitation, it is concluded that rehabilitation evaluation, rehabilitation phases and obstacle analysis should be taken as references by acupuncturists to reinforce the therapeutic effect and creditability of acupuncture treatment on cerebral apoplexy.
Acupuncture Therapy ; methods ; Hemiplegia ; rehabilitation ; therapy ; Humans ; Stroke ; therapy ; Stroke Rehabilitation

Adult ; Cerebrospinal Fluid Rhinorrhea ; surgery ; Endoscopy ; adverse effects ; Humans ; Male ; Pneumocephalus ; etiology

Amyloidosis ; pathology ; Female ; Gadolinium ; Heart Diseases ; pathology ; Humans ; Magnetic Resonance Spectroscopy ; methods ; Male ; Middle Aged ; Myocardium ; pathology

Angina Pectoris ; drug therapy ; Animals ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Phytotherapy ; Technology, Pharmaceutical

Objective Patients with severe acute pancreatitis ( SAP) always suffer decrease in gastrointestinal motility , even gastrointestinal failure.The article aimed to investigate the changes of vasoactive intestinal peptide (VIP) in the myenteric plexus of the gastric antrum in rats with severe acute pancreatitis ( SAP) complicated by gastrointestinal dysmotility . Methods Twenty Sprague Dawley rats were randomly allocated into two groups:control group and SAP group .Acute pancreatitis was induced by intraductal infu-sion of 5%sodium taurodeoxycholate .24 h after operation , records were made on pathological evaluation of pancreatic lesion , amylase, C-reactive protein ( CRP) , gastric emptying rate and the percentage of VIP neurons in the total neurons . Results Compared with the control group, the gastric emptying rate in the SAP group was significantly lower ([31.49 ±3.96]% vs [70.99 ±1.82]%).The score of pancreatic lesion, amylase, CRP and the percentage of VIP neurons was significantly higher ([14.63 ±1.06]score vs [1.60 ± 0.52]score, [2061.25 ±434.86]U/L vs [360.20 ±30.29]U/L, [140.10 ±17.07]μg/mL vs [35.71 ±6.43]μg/mL, [22.45 ± 4.10]%vs [10.72 ±1.92]%)(P<0.05). Conclusion Plas-ticity took place in VIP neurons in the myenteric plexus of gastric an-trum in rats with SAP complicated by gastrointestinal dysmotility , which was connected with neural mechanism underlying SAP compli-cated by gastrointestinal dysmotility .

OBJECTIVE:To investigate the effect of Xuebijing injection on coagulation function and prognosis in patients with sepsis. METHODS:50 patients with sepsis were randomly divided into control group and observation group according to the hospi-talization sequence,with 25 cases in each group. Control group received conventional treatment,and observation group was addi-tionally given Xuebijing injection(50 ml added into 5% Glucose solution or 0.9% Sodium chloride solution 250 ml intravenously, bid) on the basis of conventional treatment. Treatment course lasted for 7 d. The coagulation function,APACHE Ⅱscore after 7 days of treatment and 28 d mortality were compared between 2 groups. RESULTS:After 7 d treatment,the coagulation indexes were improved significantly in 2 groups compared with before treatment,and the APACHEⅡscores were decreased significantly in both groups;the observation group were significantly better than the control group,with statistical significance (P<0.05). After followed up for 28 d,the mortality rate of 2 groups were 16% and 28%,there was no statistical significance (P>0.05). CON-CLUSIONS:Xuebijing injection can inhibit blood clotting activation,correct the coagulation disorders,and improve the sepsis se-verity.

ObjectiveTo observe the effects of acupuncture combined with massage on shoulder subluxation and motor function recovery of the upper extremities in patients with hemiplegia after stroke.Methods60 hemiplegic patients were randomly divided into two groups for treatment with acupuncture cooperates with massage or usual rehabilition, respectively. The recovery of the patient's shoulder subluxation and movement function of upper extremities were evaluated 2 months after treatment. ResultsThe shoulder subluxation and movement function of the upper extremities were improved after treatment with both therapies (P<0.01), and acupuncture cooperates with massage showed better effect (P<0.01). ConclusionAcupuncture cooperates with massage can facilitate the recovery of shoulder subluxation and motor function of the upper extremities after hemiplegia.

ObjectiveTo observe the effects of XinShu parenteral solution (XSPS) on the activation of platelet, the activity of fibrinolysis system after intima denudation of rabbits.Methods20 male Japanese white rabbits (2.5±0.5)kg were randomly divided into the control group and XSPS group .The celiac arterial endothelium of all rabbits were denuded with balloon. Before the operation and 3d, 7d, after balloon denudation, vein blood samples were obtained from each group rabbits for measurement of α granule membrane protein of platelets(GMP-140), tissue-type plasminogen activator(t-PA) and plasminogen activator inhibitor-type Ⅰ(PAI-1).ResultsPlasma GMP-140 and PAI-1 activity obviously elevated after balloon injury, and there was a little elevation in plasma t-PA activity in control group. Activity of plasma GMP-140 in XSPS group remained bottom level after balloon injury, and there was a significant increase in plasma t-PA activity and a marked reduce in PAI-1 activity in XSPS group. There was a notable difference between group B and group C (P<0.05). ConclusionXSPS obviously inhibits platelet activation, and improves fibrinolysis activity after balloon injury.