1.Complications of femtosecond laser corneal small incision lenticule extraction
Qing-Hong, LIN ; Lin, ZHENG ; Qian, WANG
International Eye Science 2017;17(7):1378-1380
AIM:To investigate the safety and complications of femtosecond laser corneal small incision lenticule extraction(SMILE) procedure and discuss the prevention and treatment.METHODS: We retrospectively studied the complications of 403 patients(799 eyes) with myopia and myopic astigmatism treated by SMILE.RESULTS: All the patients underwent the operation successfully.Only 1 case(1 eye)suffered from dark spot and changed to femtosecond laser-assisted LASIK(FS-LASIK), 5 cases(5 eyes, 0.6%) suffered from the suction loss, 11 cases (17 eyes, 2.1%) developed opaque bubble layer.All patients gained perfect uncorrected visual acuity(UCVA) (20/20).The best corrected visual acuity(BCVA) did not decrease after operations.The incidence of haze and diffuse lamellar keratitis was low (0.3% and 0.4%, respectively)and no other complications were observed.There was 9 eyes in 6 patients (1.1%) found regression of refraction at 6mo after surgery, while the UCVA of rest patients reached 1.0 at 3mo after surgery.CONCLUSION: The SMILE procedure has high safety for myopia and myopic astigmatism.Effective prevention and management of the complications is the key to achieve the satisfactory visual acuity.
2.Three cases of heart valve spongy lymphangioma.
Hong ZHAO ; Li LI ; Lin-Lin WANG
Chinese Journal of Cardiology 2010;38(12):1127-1128
Adult
;
Aged
;
Female
;
Heart Neoplasms
;
pathology
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Heart Valves
;
pathology
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Humans
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Lymphangioma
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pathology
;
Middle Aged
3.Bilateral laryngeal granulomas after endotracheal intubation.
Zhi-hong LIN ; Hua-lin WANG ; Hui-e WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(1):67-68
Adult
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Aged
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Female
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Granuloma, Laryngeal
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etiology
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Humans
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Intubation, Intratracheal
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adverse effects
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Male
4.Efficacy of transcutaneous electrical acupoint stimulation (TEAS) for menopausal insomnia and its effect on serum hormone levels
Journal of Acupuncture and Tuina Science 2020;18(3):197-202
Objective: To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation (TEAS) for menopausal insomnia. Methods: A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group, with 40 cases in each group. The patients in the control group received conventional Western medication treatment, and the patients in the observation group received TEAS on the basis of conventional Western medication treatment. The treatment for both groups lasted for 4 weeks. Before and after treatment, Pittsburgh sleep quality index (PSQI) and modified Kupperman scale were evaluated, and the serum levels of estradiol (E2) and follicular stimulating hormone (FSH) were measured. The therapeutic efficacy was evaluated after treatment. Results: After treatment, the total effective rate of the observation group was significantly higher than that of the control group (P<0.05); in the control group, the improvement of PSQI score was significant (P<0.05), while the change of modified Kupperman score was insignificant (P>0.05); the PSQI and Kupperman scores in the observation group were significantly improved after treatment (both P<0.05), and there were significant differences between the observation group and the control group in PSQI and Kupperman scores (both P<0.05). After treatment, the serum E2 and FSH levels in the control group were not statistically different from those before treatment (both P>0.05); the serum E2 level was significantly increased (P<0.05), and the FSH level was decreased (P<0.05) in the observation group after treatment, and the between- group differences in serum levels of E2 and FSH were significant (both P<0.05).Conclusion: TEAS plus conventional Western medication in treating menopausal insomnia is effective, and can significantly improve the symptoms of insomnia and menopause, which may be related to the regulation of serum E2 and FSH levels.
5.Ethics Thought of AIDS Epidemic Tendency and It's Harmfulness
Ming WANG ; Lin XU ; Hong XIAO ;
Chinese Medical Ethics 1994;0(05):-
This paper discussed AIDS epidemic sityation and it's tendency, AIDS harmful-ness to human beings health and social economic development. The dangerous factors of AIDS epidemic in china is pointed out. prsvent and treatment AIDS is urgency.
7.Clinical study of the clusters of diffuse lamellar keratitis after laser corneal refractive surgery
International Eye Science 2017;17(6):1150-1152
AIM: To investigate the potential causes and management of the clusters of diffuse lamellar keratitis (DLK) after laser corneal refractive surgery.METHODS: The study enrolled 98 eyes (53 patients) complicated with DLK after receiving laser in situ keratomileusis (LASIK), FS-LASIK or small-incision lenticule extraction (SMILE) in our center from February 10th,2016 to February 22th,2016.They were given clinical classification treatments according to corneal layer inflammatory extent and then followed up after 1, 3, 5, 7, 10d and 1mo.RESULTS: The clusters of DLK occurred 5 times in the study period.The incidence and degree of DLK significantly decreased after changed the sterilization, surgical equipments, temperature and humidity of the operating room.There were 80 eyes (82%) had stage 1 DLK, 11 eyes (11%) had stage 2, 4 eyes (4%) had stage 3 and 3 eyes (3%) had stage 4.The incidence of DLK after FS-LASIK was 40% (79 eyes in 42 patients), that after LASIK assistant by Hastome keratome was 45% (10 eyes in 5 patients), that after SMILE was 20% (9 eyes in 6 patients).After intensive treatment, as glucocorticoid treatment and flap lifting flushing, all cases recovered within 1mo.CONCLUSION: The outbreak of DLK may be associated with the disposable item, flushing liquor, temperature and humidity of the operating room.Early diagnosis, prevention and treatment are the key of decreasing the incidence of DLK.
8.The study of therapy of the hypoplastic myelodysplastic syndrome
Lin HUANG ; Hui-Hui LIU ; Hong WANG ;
Cancer Research and Clinic 2006;0(11):-
Hypoplastic myelodysplastic syndrome(Hypo-MDS),with the derangement of BM texture,is characterized by the hypoplasia of bone marrow(BM)accompanied with the deterioration of MDS. Hitherto there isn't a definite therapeutic definition about Hypo-MDS. Is therapy should be paid more attention to. This article introduces the study of therapy of Hypo-MDS.
9.Single cell RNA sequencing technology applicated for drug discovery
Acta Pharmaceutica Sinica 2023;58(9):2551-2559
Single cell RNA sequencing (scRNA-seq) is an advanced technology to study the transcriptome information at the single cell level. The application of this technology can attribute to analyze the heterogeneous map of cells in the process of disease development, and precisely identify the specific cell subsets that are responsive to pharmacological therapy. Currently, scRNA-seq technology has been widely applied in the field of drug research, including studies on therapeutic targets, drug-induced adverse reactions, drug resistance and vaccine. This work reviews the application of scRNA-seq technology in drug discovery, which offers a scientific basis for personalized and accurate medication therapy.
10.Design of Control System of Charge Evasion in Medical Equipment Based on Embedded System
Zhen LIU ; Hong WANG ; Jinan LIN
Chinese Medical Equipment Journal 2009;30(7):54-56
Obiective To solve the problem of charge evasion in medical equipment and improve the management of medical equipment and increase income of the hospital.Methods The control system was designed and used based onembedded system as real-time monitor in the medical equipment. Results This system can realize the real-time monitor of the medical equipment and improve the management of hospital. Conclusion The system resolves the problem of charge evasion effectually and increases the income of the hospital.