1.Evaluating the clinical effect and safety of gatifloxacin in the treatment of community acquired pneumonia
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
0.05).Conclusion Gatifloxation is safe and efficient in the treatment of community acquired pneomonia.
2.A comparative study of treatment for necrosis of the femoral head by vascularized iliac bone flap combined with or without tantalum screw
Benjie WANG ; Dewei ZHAO ; Lin GUO
Chinese Journal of Microsurgery 2009;32(4):271-274,插1
-mid stage ONFH. It provided good blood supply and enough mechanical support as to reduce the progress of femoral head collapse.
3.Evaluation of Patients Treated with Lipo-prostaglandin E 1 for Chronic Severe Type B Hepatitis by MELD Prognosis Analysis
Chusheng ZHAO ; Shaorui LIN ; Genglong GUO
China Pharmacy 2001;0(09):-
OBJECTIVE:To investigate the therapeutic effect of Lipo-prostaglandin E 1 (Lipo PGE 1 )on chronic severe type B hepatitis by MELD(Model for end-stage live disease)prognosis analysis.METHODS:Of a total of115cases with chronic severe type B hepatitis,57were randomly assigned to receive a common combined therapy and58to receive a common combined therapy plus Lipo PGE 1 for4weeks,the MELD score and prognosis of diseases of the2groups were assessed.RE-SULTS:The MELD score in the treatment group(20.12?8.97)was lower than that of the control group(24.76?10.41)after4weeks’treatment(P
4.Reliability and validity of Chinese version of the Osteoporosis Knowledge Assessment Tool in the elderly
Qiyun GUO ; Mujie GUO ; Lin ZHANG ; Pengpeng ZHAO ; Lina GUO ; Han GAO ; Kun LIU
Chinese Journal of Practical Nursing 2015;31(7):512-515
Objective To test the reliability and validity of the Chinese version of Osteoporosis Knowledge Assessment Tool (OKAT).Methods The English version of OKAT was introduced and the Chinese version was confirmed by translation,revision,retroversion and expert discussion.A sample of 400 community-living aged people were recruited to complete the OKAT (Chinese version).Internal consistency test,split-half reliability,correlation analysis,items analysis,content validity,exploratory factor analysis,confirmatory factor analysis and ROC curve were used for examination.Results The Cronbach's α of the total scale was 0.821.The split half reliability coefficient was 0.934,test-retest reliability was 0.866,inter rater reliability coefficient was 0.786,the correlations between items and total scale ranged from 0.163 to 0.542.A two-factor model containing 20 items was got by exploratory factor analysis,the cumulative contribution rate of the items was 75.528 percent.The confirmatory factor analysis revealed a good model fit.Conclusions The Chinese version of the OKAT in the elderly is proved to be reliable and valid.It can be used to assess osteoporosis for the aged people in China.
5.Expression of hyaluronan in laryngeal carcinoma.
Zhao HAN ; Guo-jing LIN ; Jian-min HUANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(11):867-868
Adult
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Aged
;
Carcinoma, Squamous Cell
;
metabolism
;
pathology
;
Female
;
Humans
;
Hyaluronic Acid
;
metabolism
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Laryngeal Neoplasms
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metabolism
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pathology
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Male
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Middle Aged
;
Neoplasm Staging
6.Twenty-seven cases of urinary retention after stroke treated by point-application combined with acupuncture.
Shi-Lin SUN ; Zhong-Ren SUN ; Zhao-Xia GUO
Chinese Acupuncture & Moxibustion 2012;32(10):933-934
Acupuncture Points
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Acupuncture Therapy
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Adult
;
Aged
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Drugs, Chinese Herbal
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therapeutic use
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Female
;
Humans
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Male
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Middle Aged
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Stroke
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complications
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Urinary Retention
;
drug therapy
;
therapy
7.Cemented hemiarthroplasty for femoral neck fractures in elderly patients
Zhigang LI ; Dewei ZHAO ; Lin GUO ; Chongjun XIA
Chinese Journal of Tissue Engineering Research 2012;16(26):4796-4800
BACKGROUND: A discussion is ongoing whether the elderly patients with femoral neck fractures should be treated with a non-cemented or a cemented hemiarthroplasty.OBJECTIVE: To evaluated the results of cemented hemiarthroplasty for femoral neck fractures in the patients older than 85 years with high-risk clinical problems and functional outcomes.METHODS: Thirty-two patients with femoral neck fractures were treated with cemented bipolar hemiarthroplasty. X-ray examination after operation was done at 1, 3 and 6 months and annually in all patients. The mean follow-up period was 2 to 5 years.RESULTS AND CONCLUSION: Medical complications occurred in five patients (16%) and four patients (25%) died within the follow-up period. Dislocation occurred in one patient (3%). None of the patients had heterotopic ossification. The mean Harris-hip score was 84. Cemented hemiarthroplasty can provide stability, security and good outcomes for the treatment of femoral neck fractures in elderly patients.
8.Primary research on genetic relationship among main populations of Salvia miltiorrhiza and genuineness of herb
Baolin GUO ; Sheng LIN ; Yuxiu FENG ; Yangjin ZHAO
Chinese Traditional and Herbal Drugs 1994;0(12):-
Object To research on genetic relationship among the main populations of Salvia miltiorrhiza Bge. and the genuineness of the herb. Methods From main distributed places, 44 samples (including nine populations) were analyzed by RAPD. The data of amplified bands were analyzed by the software NTSYS-pc and AMOVA. Results (1) From more than 100 primers, 11 primers producing polymorphism and reproduceable bands were selected, 129 bands were amplified. (2) The percentage of polymorphic bands within different populations were 20.9%-55.0%. (3) The cluster map including all samples were obtained by UPGMA. In the map, there were six cluster groups and three individuals outside the groups. The branch with five samples of Zhongjiang Sichuan population were far from other samples in genetic distance. (4) According to the distribution provinces five groups were divided in genetic variance analysis. Genetic variance 80.44% existing within population, 8.29% among populations and 11.27% among groups. Conclusion (1) The genetic diversity within population of S. miltiorrhiza is plentiful. (2) The seeds of the cultivated population in Shandong and Henan Provinces come from the wild ones of same places. The cultivated plants lack artificial selection. The decrease of chemical compound is mainly due to the undesired condition of cultivating. (3) The genetic differentiation among the populations from different provinces is unbalance. Two population from Zhongjiang Sichuan and Chengde Hebei are far from the other population. (4) The genuineness of Radix Salviae Miltiorrhizae should be decided according to modern evaluation system. The herbs from some places of Shandong and Henan should be genuine ones.
9.Comparison of main constituents of Herba Cistanche and cultured cells of Cistanche salsa
Lin ZHAO ; Zhigang GUO ; Ruizhi LIU ; Suqi SUN
Chinese Traditional and Herbal Drugs 1994;0(07):-
Object To study the difference of phenylethanoid glycoside between the cultured cells of Cistanche salsa (C. A. Mey.) Benth. et Hook. f. and Herba Cistanche. Methods Making comparison by means of FTIR and HPLC technique. Results Using the FTIR technique, the infrared spectrum of cutured cell of C. salsa was similar to that of native Herba Cistanche at a certain extent. The HPLC analysis indicated that the main chemical constituents in cultured cells of C. salsa were similar to that of native Herba Cistanche while considerable difference of constituents was found between them. Conclusion On the whole, there are much more constituents in the cultured cells of C. salsa comparing with the native Herba Cistanche. The content of echinacoside and acteoside in the cultured cells is much higher than that in the native Herba Cistanche.
10.The feasibility study of repairment of articular cartilage defects with bone marrow-derived mesenchymal stem cells seeded on acellular amniotic membrane
Hao CHEN ; Zhijin ZHANG ; Dewei ZHAO ; Lin GUO
Chinese Journal of Microsurgery 2014;37(3):254-257
Objective To study the effect of repairment of articular cartilage defects in non weight-bearing area of rabbit with bone marrow-derived mesenchymal stem cells (BMSCs) seeded on human acellular amniotic membrane (HAAM).Methods From July 2012 to March 2013,bone marrow-derived mesenchymal stem cells were isolated and purified from rabbit in vitro.The cells were seeded on human acellular anniotic membrane at the concentration of 1.63 × l05/cm2.From 7 days to 8 days after cultured,the complexes of BMSC and HAAM were examined under electronmicroscope,light microscope and by HE stain.Full thickness empty defects measuring 4 mm in diameter by 3 mm depth were prepared in femoral intercondylar fossa of 24 rabbits.The rabbits were randomized into two groups:group A and group B with 12 each group.The defects of right knees were served as control and the left as experimental group.BMSCs/HAAM composite was cultured and then transplanted into the defect of left knee joint in group A as group BMSCs/HAAM and HAAM into group B as group HAAM.These rabbits were killed at 4 and 12 weeks after surgery in each group and the newly cartilage samples were evaluated grossly,histologically are graded.Results In the 4th and 12th week after the operation,the regenerated tissue were white,soft and smooth.Chondrocytes were found in the tissue In the 12th week,the morphology,distribution and arrangement of the regenerated tissues were similar to normal cartilage in the knees with HAAM-BMSCs transplantation.The regenerated tissues grew to be integrated with the surrounding normal cartilage with obscure boundary between them.Chondrocytes were found in all layer of the tissue,surrounding normal cartilage with obscure boundary between them.In the HAAM transplantation,the rough surface of regenerated tissue sunk obviously and the fibmblasts in all layer were found.While there were no regenerated tissue in the control side.Conclusion BMSCs seeded on HAAM could repair the articular cartilage defects of femoral intercondylar fossa from rabbits.