1.Clinical Research on Treatment of Linguistic Disturbance due to Infantile Cerebral Palsy with Acupuncture Dominantly
International Journal of Traditional Chinese Medicine 2008;30(2):144-145
Objective Research and analysis on the clinical effect of rehabilitation of linguistic disturbance of child cerebral palsy patients,mainly through the treatment of acupuncture.Methods Effect comparison between the treatments of acupuncture and the only common way of 121 cerebral palsy children.Results The treatment mainly by acupuncture was obvious better than the common one.Conclusions The treatment mainly by acupuncture is one of the effective ways of linguistic disturbance of infantile cerebral palsy,and there are good prospects and special advantages for the treatment of Traditional Chinese Medical Science
2.Relationship between myeloid-derived suppressor cells and related immune cells in the process of tumor progression
International Journal of Surgery 2013;(6):405-408
Myeloid-derived suppressor cells are a heterogeneous population of early myeloid progenitors,immature granulocytes,macrophages,and dendritic cells at different stages of differentiation.These cells have the capacity to suppress both the innate immunity response mediated by the cytotoxic natural killer cells and natural killer T cells,and the adaptive immune response mediated by CD4+ and CD8+ T cells.In addition,myeloid-derived suppressor cells have close links with macrophages,dendritic cells,regulate T cells and so on,and also play an important role in the process of tumor progression.
3.Acupucture at Dong's extra acupoint combined with exercise for 61 cases of acute chest.
Chinese Acupuncture & Moxibustion 2014;34(1):71-72
Acupuncture Points
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Acupuncture Therapy
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Adolescent
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Adult
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Aged
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Chest Pain
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therapy
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Exercise Therapy
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Female
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Humans
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Male
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Middle Aged
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Young Adult
4.Prediction of peripheral blood lymphocytes radiosensitivity in normal tissue radiation damage in oncology patients with radiotherapy
Xiaoshuang NIU ; Yong LIU ; Lin KONG
China Oncology 2014;(1):57-61
Patients treated with radiotherapy (RT) might experience a large variation in normal tissues. Severe radiation damage in a minority of patients limits the doses that might be safe given to the majority. The possibility of predicting such radiation-induced damage would provide a better treatment schedule for the patients. Several predictive tests in peripheral blood lymphocytes such as initial DNA damage, radiation-induced apoptosis and genetic variation have been proposed to know the individual sensitivity of patients to the radiotherapy schedules. This study aimed to summarize the main studies regarding to this ifeld.
5.C_3 POLYMORPHISM IN CHINESE POPULATION IN SHAANXI
Mingzhan XUE ; Xiaohong NIU ; Tian LIN
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(01):-
273 chinese have been studied with high voltage electrophoresis and immumofixation to survey the polymorphism of the third component of human complement in Shaanxi Provice Two C_3 phenotypes were found in this population, they are C_3SS and C_3FS The frequencies of C_3SS and C_3FS are 98.53% and 1.47% respectively. The frequency of C_3S gene is 0.9926 and C_3F gene 0.0073. These results are similar to other studies in China and this group was in Hardy-Weinberg equilibrium. Compared with Negro and Caucasian, the chinese population in Shaanxi Province has a significant difference in C_3 polymorphism.
6.Experimental study of gene therapy on human gastric cancer with HSV-TK/GCV system
Zhongwei XU ; Sanren LIN ; Dadi NIU
Chinese Journal of Digestion 1996;0(S1):-
2000 fold). In bystander effect experiment, the death rate of mixed cells was still over 50% even when they contained only 20% TK+ target cells. Fourteen days after nude mice bearing tumors were treated i.p. with GCV, the mean weight and volume of transfected tumors were less than those of untransfected tumors (P
7.Metagenomics and their application in the research of marine natural drugs
Tong ZHOU ; Rongli NIU ; Xiukun LIN
Chinese Journal of Marine Drugs 1994;0(02):-
Objective To study the chemical constituents of marine sponge Craniella australiensis collected from the South China Sea.Methods Compounds were isolated and purified by column chromatography and their structures were identified based on spectral analyses and chemical evidence.Results Four compounds were isolated from the ethanol extract and identified as: ?-sitosterol(Ⅰ),3?,6?-stigmast-4-en-3,6-diol(Ⅱ),1,12-diazacyclodocosane-2,11-dione(Ⅲ),uracil(Ⅳ).Conclusion All these compounds were isolated from this sponge for the first time.
8.The research on MRI for differential diagnosis of benign and malignant lesions of SPN
Chungang ZHAO ; Lin XU ; Yaling NIU
China Medical Equipment 2017;14(9):57-60
Objective:To investigate the clinical value of magnetic resonance imaging (MRI) in differential diagnosis for benign and malignant lesions of solitary pulmonary nodules (SPN).Methods: 120 patients with SPN were enrolled in the retrospective analysis, and all of them underwent scan of MR including MRI, DCE-MR and diffusion weighted imaging (DWI) before their surgery. All of patients received detection of pathology or histopathological examination after their surgery, and the ADC values under different b values of dispersion sensitivity factor (300 s/mm2, 500 s/mm2 and 800 s/mm2) were compared.Results:Under the conditions both of 300 s/mm2 and 800 s/mm2, the differences of ADC value between benign nodule and malignant nodule were not statistically significant (t=1.195,P>0.05). And under the condition of 500 s/mm2, the ADC value of benign nodule was significantly higher than that of malignant nodule (t=4.313,P<0.05), and at this time, the sensitivity, specificity, rate of missed diagnosis and misdiagnosis rate of the differential diagnosis for benign and malignant lesions of SPN by using MR were 85.71%, 74%, 14.9% and 26%, respectively.Conclusion: MR examination has higher sensitivity in differential diagnosis for benign and malignant lesions of SPN, and it has a certain clinical value when it is used as early detecting method.
9.Advancement of Balance Function Assessment for Stroke Patients (review)
Chinese Journal of Rehabilitation Theory and Practice 2016;22(6):667-671
Balance function assessments for stroke patients include instruments and scales. The instruments consist of static balance test systems and dynamic balance test systems. The commonly used static balance test systems include balance performance monitor (BPM) and Tetrax balance test system, and the dynamic balance test systems include Active Balancer EAB-100 and Pro-Kin 254. The balance scales contained Berg Balance Scale, Postural Assessment Scale for Stroke Patients, Timed Up and Go Test, Fugl-Meyer Assessment-Bal-ance, Tinetti Performance Oriented Mobility Assessment, and Five-Times-Sit-to-Stand Test, etc. This article reviewed the features and indi-cations of them.
10.Preliminary implementation and effect of clinical pathways for chronic Keshan disease in endemic areas
Chinese Journal of Endemiology 2013;32(5):500-503
Objective This present study explores and evaluates the effect of preliminary implementation in the clinical therapy programs for patients with chronic Keshan disease (CKD) in the disease seriously-affected endemic areas.Methods In 2010,seventy-six CKD patients with heart failure were chosen from Huangling and Xunyi Counties in Shaanxi Province,where incidences of CKD were high.Besides taking sodium selenite,all patients were given treatment with fixed prescription,which included angiotensin-converting enzyme inhibitor (captopril),β-blocker (propranolol),diuretics (hydrochlorothiazide,spironolactone) and cardiac (digoxin) for 4 months.The changes before and after treatment were analyzed,which included the changes of heart function by the United States of America New York Heart Association(NYHA) fractionation,cardiothoracic ratio,electrocardiogram,left ventricular ejection fraction(EF) and fractional shortening(FS).The therapeutic effect was subsequently evaluated.Results Seventy-four cases of the seventy-six CKD patients completed the treatment observation.The improvement rate of heart function was 81.1% (60/74) after treatment.The elimination rates of ectopic rhythm,conduction block and ST-T changes were 37.5% (9/24),2.7% (1/36) and 26.9% (7/26),respectively.The cardiothoracic ratios of heart function NYHA Ⅱ,Ⅲ and Ⅳ were 0.504 ± 0.051,0.572 ± 0.054 and 0.632 ± 0.063 before treatment.After treatment,the cardiothoracic ratios were 0.486 ± 0.048,0.538 ± 0.046 and 0.607 ± 0.048,which were reduced in all groups (t =2.643,6.641,3.005,all P < 0.05),while the D-value of cardiothoracic ratio changes before and after treatment was not significantly different(F =3.005,P > 0.05).Both the mild reduction group(35%≤EF < 50%) and the moderate-severe group(EF < 35%) EF were (43.62 ± 4.58)%,(27.57 ± 3.69)% before treatment and were (48.21 ± 10.01)%,(36.57 ± 6.60)% after treatment,EF were increased in the two groups,while the changes before and after treatment were significantly different(t =-2.911,-3.334,all P< 0.05).The EF D-value of the two groups was (4.59 ± 8.48)% before treatment and was (9.00 ± 7.14)% after treatment,which were not significantly different(P > 0.05).FS was higher compared with pre-treatment in FS reduction group(FS < 25%) and the changes before and after treatment[(19.75 ± 2.88)%,(21.92 ± 5.67)%] were significantly different(t =-2.297,P < 0.05).Conclusions This study shows that the feasibility of clinical treatment of patients with CKD is very promising.The treatment of fixed prescription is effective.