Differences are existed in two textbooks of doctor-patient communication between China and foreign countries concerning perspectives of doctor-patient communication,teaching goals and applicable scope based on the consensus on importance of doctor-patient communication and education training.Contents in textbooks of china emphasize the logic of discipline while that of foreign countries pay attention to the logic of clinical treatment.The advantages of textbooks of China are having strong theoretical basis and ample contents while those of foreign text books are practicability and effectiveness.Some suggestions which to benefit the textbook development of Chinese doctor-patient communication has been offered:textbooks of doctor-patient communication in our country should be separated from those of nursing communication; advantages and experiences of foreign textbooks should be drew from; in-depth development of doctor-patient communication theory research and education reform should be conducted; diversification of teaching materials of doctor-patient communication should be gradually perfected ; teaching quality of doctor-patient communication should be improved.

Objective:To investigate the clinical efficacy of intramedullary nailing combined with bone cement in repair of segmental bone defects after tumor resection.Methods:A retrospective analysis was conducted of the 5 patients with malignant bone tumor who had been treated at Department of Orthopaedics, Qiannan People's Hospital from April 2018 to September 2019 for remaining segmental bone defects following limb salvage surgery. They were 4 males and one female, aged from 11 to 55 years (average, 35.4 years). Their defects ranged from 6 to 21 cm (average, 12.3 cm) after tumor resection. By the Karnofsky performance score (KPS) for long-term quality of life, all of them scored less than 50 points. Of them, 3 were treated by interlocking intramedullary nails and bone cement filling, and 2 by elastic intramedullary nails and bone cement filling. In the 2 cases with defects of 21 cm and 13 cm, the fixation was assisted by a plate and an external fixator. Defect length after resection, operation time and intraoperative bleeding were recorded; the efficacy was evaluated by the Enneking functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system, visual analogue scale (VAS), and KPS.Results:All the 5 patients had uneventful surgery, with operation time ranging from 112 to 225 min (average, 154.2 min), intraoperative bleeding from 300 to 500 mL (average, 382 mL), and defect length after resection from 6 to 21 cm. The 5 patients were followed up for 6 to 28 months. Of them, 2 died of disease progression 6 and 7 months after surgery, respectively. According to the Enneking's evaluation, one patient scored 28 points, 2 patients 23 points and 2 patients 21 points, giving a high degree of satisfaction. Their VAS scores 6 months after surgery ranged from 1 to 6, averaging 3.6; their postoperative KPS scores ranged from 60 to 80, averaging 72.Conclusion:In repair of segmental bone defects after tumor resection, intramedullary nailing combined with bone cement filling can relieve pain of patients and lead to satisfactory short-term curative efficacy.

Objective To reverse P-glycoprotein-mediated muhiple drug resistance using RNA interference(RNAi)in cultured rat astrocytes.Methods Astroeytes overexpressing P-glyeoprotein induced by coriaria lactone were transfected with the short-hairpin RNA expression vector-p-SIREN shuttle designed to target Mdrl mRNA.The mRNA level of Mdrl gene was evaluated by real-time PCR;the P-glycoprotein was examined by immunocytochemistry and image analysis,meanwhile the rhodamine efflux was assessed by flow cytometry.Results The astrocyte model overexpressing P-glycoprotein were established and successfully transfected with the short-hairpin RNA expression vector-p-SIREN shuttle.The mRNA level of Mdrl gene was knocked down by 67.70%(P

Purpose:To study the clinical significance of CD44 level in tumor cells of esophageal carcinoma patients. Methods:Sixty-five esophageal carcinoma cases were examined to observe the CD44 expression rate in tumor cells and nor- mal mucosal cells by flow cytometry.These data were clinicopathologically analyzed and compared with statistical methods. Results:The CD44 expression rate in tumors cells of esophageal carcinoma was obviously higher than that in normal mucosal cells (P

Female ; Humans ; Laser Therapy ; methods ; Middle Aged ; Semicircular Canals ; surgery ; Vertigo ; etiology ; surgery

A new steroid with a long cross-conjugation structure, 15a-hydroxy-(22E, 24R)-ergosta-3, 5, 8 (14), 22-tetraen-7-one (1), was isolated from the marine-derived fungus Aspergillus aculeatus. Its structure was established by the extensive spectroscopic analyses, and its cytotoxicities against P388, HL-60, and PC-3 cell lines were measured in vitro.
Animals ; Aspergillus ; chemistry ; Cell Line, Tumor ; drug effects ; Cholestenones ; chemistry ; isolation & purification ; pharmacology ; HL-60 Cells ; drug effects ; Humans ; Inhibitory Concentration 50 ; Molecular Structure ; Seawater ; microbiology

Adjuvants, Immunologic ; therapeutic use ; Antigen-Presenting Cells ; drug effects ; immunology ; Combined Modality Therapy ; Dendritic Cells ; drug effects ; immunology ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Immunotherapy ; Medicine, Chinese Traditional ; Neoplasms ; drug therapy ; immunology ; Phytotherapy

Adult ; Capsules ; Dinoprost ; blood ; Drugs, Chinese Herbal ; therapeutic use ; Dysmenorrhea ; drug therapy ; Female ; Hemorheology ; drug effects ; Humans ; Phytotherapy

Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Mikulicz' Disease ; Salivary Gland Diseases

Objective: To observe the clinical efficacy of deep electroacupuncture (EA) at Baliao points in treating stress urinary incontinence (SUI). Methods: A total of 60 female patients with SUI were divided into two groups according to the order of consultation, with 30 cases in each group. The control group was treated with pelvic floor muscle training. The treatment group was treated with deep EA at Baliao points [Shangliao (BL 31), Ciliao (BL 32), Zhongliao (BL 33) and Xialiao (BL 34)]. Results: The total effective rate was 93.3％ in the treatment group, versus 33.3％ in the control group, and the total effective rate of the treatment group was significantly higher than that of the control group (P<0.05). After treatment, the scores of international consultation on incontinence questionnaire-short form (ICIQ-SF) and the volume of urinary leakage in both groups were lower than those before treatment (all P<0.05), and the ICIQ-SF score and the volume of urinary leakage in the treatment group were lower than those in the control group (both P<0.05). Conclusion: Deep EA at Baliao points with long needles can improve the clinical symptoms in female patients with SUI, and it has a better curative effect than pelvic floor muscle training.