1.Study of characteristic differences using CT and MRI for intracranial hemangiopericytoma and meningiomas of different pathological type
Journal of Practical Radiology 2015;(4):537-540
Objective To study the characteristic differences using CTs and MRIs between intracranial hemangiopericytomas (HPCs)and meningiomas of different pathological type.Methods 8 cases of HPC and 5 1 cases of meningioma approved by patholo-gy were selected.All cases underwent MRIs,CTs and enhancements before operation.The imaging characteristics of these tumors were analyzed with chi-square test.Results Compared with atypical meningioma,tumor bleeding(χ2 = 1 1.484),blood vessel flow void phenomenon(χ2 =8.571),skull damage(χ2 =5.529)showed remarkably significant statistical differences(P <0.05);compared with malignant meningioma,tumor bleeding(χ2 =1 1.484),blood vessel flow void phenomenon(χ2 = 1 1.429)showed remarkably significant statistical differences(P <0.05).Conclusion There are differences between HPC and meningiomas of different pathologi-cal type.It is helpful to improve the diagnosis level through comparative analysis of the MRI and CT findings.
2.CT Angiography of Pulmonary Embolism
Journal of Practical Radiology 2000;0(02):-
Objective To study the value and the superiority of multi-slice spiral CT angiography of pulmonary artery in combination with deep vein of lower limb in diagnosing pulmonary embolism (PE). Methods CT pulmonary angiography (CTPA) and lower limb deep vein venography were performed in all suspected patients of PE with single or multi-slice spiral CT.The number and type of the embolus were calculated.Results Among the 44 patents of pulmonary embolism,34 patents had both PE and deep vein thrombo embolism (DVT) ,10 patients had only PE.The total ratio of the PE diagnosed with single slice spiral CT and multi-slice spiral CT was 12.1% and 19.0%, respectively , there were statistical significance, (P=0.004); the ratio of the PE upon deuto-segment pulmonary arteries was 25.3% and 29.7%, respectively, there was no statistical significance, (P=0.104); the ratio of the PE below deuto-segment pulmonary arteries was 1.1% and 10.2%, respectively, there was statistical significance, (P=0.000).Conclusion The technique of angiography of pulmonary artery in combination with deep vein of lower limb in diagnosing PE is a non-invasive, fast, sensitive and specific method for PE. Multi-slice spiral CT is superior to single slice spiral CT in the diagnosis of PE.
3.Small Hepatocellular Carcinoma: The Correlation of Blood Supply Type on Multiphase Spiral CT with Immunohistochemical Findings
Liling LONG ; Bingfeng LU ; Zhongkui HUANG
Journal of Practical Radiology 1991;0(03):-
0.05).Singnificant difference of p21 positive rates was showed between tumor lack of blood supplies and arterial blood (?
4.Small Hepatocellular Carcinoma:Multivariate Regression Analysis of Correlation of Pseudocapsula Completion on Multiphase Spiral CT with Histopathological and Immunohistochemical Findings
Bingfeng LU ; Zhongkui HUANG ; Liling LONG
Journal of Practical Radiology 1996;0(04):-
Objective To study the relationship among SCT features of tumor margin and tumor size, immunohistochemical findings, grade of cell differentiation, and to explore the potency of tumor marginal features on multiphase spiral CT for evaluating biological behavior of small hepatocellular carcinoma (SHCC).Methods Multiphase spiral CT scans were performed in 30 patients with 33 lesions of SHCC (≤3.0 cm in diameter) confirmed histopathologically. Of these patients,26 were male and 4 were female. Immunohistochemical and HE staining were performed in surgical samples of all patients with SHCC. All samples' size was measured and the number of masses in each patient was counted.Results Of all masses, 6 were complete capsule, 15 incomplete capsule and 12 non-capsule. In multiple linear regression analysis, the pseudocapsula presentation and completion of SHCC on SCT were positively related with tumor size and VEGF expression, negatively with CD34 and p21, and were not in association with p53 and histological grade. Tumor size was the strongest contributor to pseudocapsula completion(R=0.5115), and then VEGF(R=0.2917), CD34(R=-0.2981) and p21(R=-0.2726), which had the similar standardized regression coefficients.Conclusion Tumor size is the strongest relative factor that influenced pseudocapsula presentation and completion of SHCC. VEGF always expressed positively in SHCC with complete pseudocapsula, and negatively in the group of SHCC with incomplete pseudocapsula or without pseudocapsula. In the group of SHCC with incomplete pseudocapsula or without pseudocapsula, p21 always express positively. Neither p53 expression nor histological grade is in association with the pseudocapsula presentation and completion of SHCC on SCT.
5.The preliminary study of kidney MSCT perfusion in diabetic nephropathy patients
Kai LI ; Liling LONG ; Chunbin LIU
Journal of Practical Radiology 2014;(6):957-960
Objective To investigate effective MSCT perfusion index and evaluate its significance in the renal function of diabetic nephropathy patients.Methods The 64-slice spiral CT perfusion scanning was performed on experimental group with 25 cases dia-betic nephropathy patients and control group with 25 cases healthy volunteers.The index including the dual-renal blood flow (BF), blood volume (BV),mean transit time (MTT),and permeability of surface (PS)were measured.At the same time,the levels of microalbumin and urinary protein (mg/24 h)were quantitated,and the blood urea and serum creatinine were measured on diabetic nephropathy patients one day before and the second day after renal CT perfusion scanning.Results All indexes of renal MSCT per-fusion,which are BF,BV,MTT and PS,were associated with 24 h quantitative urinary protein and fasting blood-glucose.Only BF and MTT were related to microalbumin and in a good correlation with indexes of diabetic nephropathy (microalbumin,24 h quantita-tive urinary protein,and fasting blood-glucose).Within them,the BF value was negatively correlated to the indexes,and the MTT was positively correlated.The area below the ROC curve of BF and MTT was more than 0.8,it indicated the good effect for the in-dexes in diagnosis of diabetic nephropathy.The usage of non-ionic contrast agent in the renal perfusion scanning process has no sig-nificant impact on the measured index values.Conclusion MSCT renal perfusion index can be used to evaluate the renal function of diabetic patients.BF,BV and MTT could be used in prediction,diagnosis and screening of DN patients,among them BF and MTT indexes were the optimal.
6.Clinical research on alterations of brain MRI and 1H-MRS in chronic hepatic disease
Liling LONG ; Xiangrong LI ; Zhongkui HUANG
Chinese Journal of Radiology 2000;0(12):-
Objective To study the abnormal findings and metabolic alterations of the brain in chronic hepatic disease with MRI and 1H magnetic resonance spectroscopy (1H-MRS) for better understanding the clinical significance of pallidal hyperintensity and the role in the diagnosis and treatment of hepatic encephalopathy (HE) . Methods Brain MRI and 1H-MRS examination were performed in 50 patients with chronic hepatic disease and 20 healthy volunteers. The pallidus index (PI) was calculated and the height of resonance peaks of Glx was measured. The correlation between PI and Child/Pugh classification, and the association between blood ammonia and the spectroscopic alterations were studied. Pre-and post-therapeutic comparative study was also conducted in 5 cases with chronic HE. Results PI was gradually increased from healthy volunteers to patients with chronic hepatitis and liver cirrhosis (1.01?0.04, 1.06?0.09, and 1.18?0.09), and the differences in PI value among them were significant (F=22.294, P
7.Multi-slice Spiral CT Lung Volumes Measurement in Predicting Diagnosis of Chronic Obstructive Pulmonary Disease
Kai LI ; Liling LONG ; Zhongkui HUANG
Journal of Practical Radiology 2001;0(09):-
Objective To evaluate the applied value of MSCT lung volumes measurement in diagnosing chronic obstructive pulmonary disease(COPD).Methods 40 patients clinically diagnosed with COPD and 26 healthy volunteers as control group underwent MSCT chest CT scanning . The relevant indicators of lung volumes were measured and calculated in comparison with the indicators of clinical lung function . The accuracy and sensitivity of every indicator of lung volumes in forecasting and screening COPD by using ROC curve method were evaluated.Results There were significant differences between the control group and the COPD group in the full expiration volume(Vex),the full inspiration volume(Vin),Vex/Vin and the ratio of the change of lung volume(P
8.MRI value of differential diagnosis in hematological diseases (a report of 94 cases)
Zhongkui HUANG ; Liling LONG ; Yingru SONG
Chinese Journal of Radiology 1994;0(06):-
0.05). Homogenous or inhomogenous high signal in aplastic anemia were detected with decreased T 1 value. Homogenous iso-intensity was revealed in acute pure red cell aplasia with normal T 1 value. Aplastic anemia and acute pure red cell aplasia had a homogenous signal on T 2WI, their T 1 value showed significant difference (P
9.MRI study of bone marrow in aplastic anemia
Yingru SONG ; Zhongkui HUANG ; Liling LONG
Chinese Journal of Radiology 1994;0(06):-
Objective To evaluate the MRI in the diagnosis of aplastic anemia (AA) and MRI changes after therapy. Methods MR imaging of lumber spine in 16 patients with AA proved pathologically were performed on 0.5 T superconductive MR unit with T 1WI, T 2WI, and STIR, slice thick 5 mm, slice gap 1 mm, matrix 180?256. Thirty cases of normal volunteers were examined as control group. Lumber spines of the two groups were studied by observation of MRI findings, measurement of the T 1 relaxation value. In AA group, the percentage of the hypointense signal areas in the centrum was calculated. Results Three patterns were classified by MR appearance in lumber spine of our cases. MR findings of pattern 1 (2 cases) were hyperintense on T 1WI, isointense on T 2WI, and hypointense on STIR, and all two cases were acute aplastic anemia (AAA). In pattern 2 (7 cases), a few irregular hypointense signals appeared in the background of hyperintense signal on all 3 sequences, and 5 of them were AAA. Pattern 3 (7 cases) demonstrated mixed irregular shape of hyperintense and hypointense signals, all 7 cases were chronic aplastic anemia (CAA). The percentage of the area of hypointense signal in AAA was significantly smaller than that in CAA (t=30 00, P
10.The Study on the Measurement of Fat Composition and Distribution with DEXA in Human Body
Yumin LU ; Zhongkui HUANG ; Liling LONG
Journal of Practical Radiology 2001;0(01):-
Objective To explore the diagnostic index of the obesity with dual energy X-ray absorptiometry(DEXA).Methods The total and local parameters(the fat composition of the arm,leg,trunk and total body) in obesity group (135 cases) and the control group(75 cases) were measured with DEXA scan.The fat composition and distribution of body in the obesity and the healthy subject in different age and sex were analysed.The diagnostic index of obesity and healthy persons determined by DEXA.Results There was no significant difference between DEXA and the platform scale to weigh all the subjects.The fat content of the arm,leg,trunk and total body in the control group and the obesity group were respectively got.The P_5(the lowest limit of 95% confidence interval of obesity fat percentage)value of the obesity male was 23(P_5=23),while the female was 29(P_5=29)).There was no significant difference between DEXA and the BMI method in the positive result of the obesity.The total body fat content in the obesity group was higher than that of the control group in each age and sex group.The fat content of the female was higher than that of the male regardless of obesity group or control group.Conclusion The obese cut off point is 23% in male and 29% in female in the total body fat content.